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Dual Oxidase Maturation Factor 1 (DUOXA1) ELISA Kits

Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. Additionally we are shipping DUOXA1 Antibodies (10) and DUOXA1 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human DUOXA1 DUOXA1 90527 Q1HG43
Anti-Mouse DUOXA1 DUOXA1 213696 Q8VE49
Anti-Rat DUOXA1 DUOXA1 311374  
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More ELISA Kits for DUOXA1 Interaction Partners

Human Dual Oxidase Maturation Factor 1 (DUOXA1) interaction partners

  1. DUOXA1 transient overexpression affected the cell-cell adhesion by modulating the actin cytoskeleton

  2. Heterodimerization controls localization of Duox (show DUOX1 ELISA Kits)-DuoxA NADPH (show NQO1 ELISA Kits) oxidases in airway cells.

Mouse (Murine) Dual Oxidase Maturation Factor 1 (DUOXA1) interaction partners

  1. DUOXA1 overexpression in muscle stem cells induces apoptosis and inhibits differentiation through DUOX1 (show DUOX1 ELISA Kits) and ASK1 (show MAP3K5 ELISA Kits).

  2. DUOXA1 is a novel p53 (show TP53 ELISA Kits)-regulated neurogenic factor involved in p53 (show TP53 ELISA Kits) dependent neuronal differentiation.

  3. Nip1 has an important role in the guidance of neuronal differentiation through ROS (show ROS1 ELISA Kits) generation and modulation of intermediate filaments

DUOXA1 Antigen Profile

Antigen Summary

Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2, respectively, which is essential for the maturation and function of the DUOX enzyme complexes. This gene encodes the DUOX1 activator or maturation factor DUOXA1. Rat studies identified a bidirectional promoter which controls the transcription of the DUOX1 and DUOXA1 genes. This protein is cotransported to the cell surface when coexpressed with DUOX1 and is retained in the endoplasmic reticulum when expressed without DUOX1 protein. The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg), a macromolecular precursor in thyroid hormone synthesis, while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg. This protein is also a p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DUOXA1

  • dual oxidase maturation factor 1 (DUOXA1) antibody
  • dual oxidase maturation factor 1 (Duoxa1) antibody
  • BC019755 antibody
  • mol antibody
  • Nip antibody
  • Nip1 antibody
  • NUMBIP antibody
  • RGD1306601 antibody

Protein level used designations for DUOXA1

dual oxidase maturation factor 1 , Numb-interacting protein , dual oxidase activator 1 , dual oxidase maturation factor 1 alpha , dual oxidase maturation factor 1 beta , dual oxidase maturation factor 1 delta , dual oxidase maturation factor 1 gamma , homolog of Drosophila Numb-interacting protein , Numb-interacting protein 1

GENE ID SPECIES
427484 Gallus gallus
487536 Canis lupus familiaris
530151 Bos taurus
713058 Macaca mulatta
100405759 Callithrix jacchus
100446897 Pongo abelii
100596084 Nomascus leucogenys
90527 Homo sapiens
213696 Mus musculus
311374 Rattus norvegicus
100653516 Sus scrofa
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