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Dual Oxidase Maturation Factor 1 Proteins (DUOXA1)

Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. Additionally we are shipping DUOXA1 Antibodies (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DUOXA1 90527 Q1HG43
DUOXA1 213696 Q8VE49
Rat DUOXA1 DUOXA1 311374  
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Top DUOXA1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

DUOXA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Dual Oxidase Maturation Factor 1 (DUOXA1) Interaction Partners

Human Dual Oxidase Maturation Factor 1 (DUOXA1) interaction partners

  1. DUOXA1 transient overexpression affected the cell-cell adhesion by modulating the actin cytoskeleton

  2. Heterodimerization controls localization of Duox (show DUOX1 Proteins)-DuoxA NADPH (show NQO1 Proteins) oxidases in airway cells.

Mouse (Murine) Dual Oxidase Maturation Factor 1 (DUOXA1) interaction partners

  1. DUOXA1 overexpression in muscle stem cells induces apoptosis and inhibits differentiation through DUOX1 (show DUOX1 Proteins) and ASK1 (show MAP3K5 Proteins).

  2. DUOXA1 is a novel p53 (show TP53 Proteins)-regulated neurogenic factor involved in p53 (show TP53 Proteins) dependent neuronal differentiation.

  3. Nip1 has an important role in the guidance of neuronal differentiation through ROS (show ROS1 Proteins) generation and modulation of intermediate filaments

DUOXA1 Protein Profile

Protein Summary

Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2, respectively, which is essential for the maturation and function of the DUOX enzyme complexes. This gene encodes the DUOX1 activator or maturation factor DUOXA1. Rat studies identified a bidirectional promoter which controls the transcription of the DUOX1 and DUOXA1 genes. This protein is cotransported to the cell surface when coexpressed with DUOX1 and is retained in the endoplasmic reticulum when expressed without DUOX1 protein. The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg), a macromolecular precursor in thyroid hormone synthesis, while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg. This protein is also a p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DUOXA1

  • dual oxidase maturation factor 1 (DUOXA1)
  • dual oxidase maturation factor 1 (Duoxa1)
  • BC019755 protein
  • mol protein
  • Nip protein
  • Nip1 protein
  • NUMBIP protein
  • RGD1306601 protein

Protein level used designations for DUOXA1

dual oxidase maturation factor 1 , Numb-interacting protein , dual oxidase activator 1 , dual oxidase maturation factor 1 alpha , dual oxidase maturation factor 1 beta , dual oxidase maturation factor 1 delta , dual oxidase maturation factor 1 gamma , homolog of Drosophila Numb-interacting protein , Numb-interacting protein 1

GENE ID SPECIES
427484 Gallus gallus
487536 Canis lupus familiaris
530151 Bos taurus
713058 Macaca mulatta
100405759 Callithrix jacchus
100446897 Pongo abelii
100596084 Nomascus leucogenys
90527 Homo sapiens
213696 Mus musculus
311374 Rattus norvegicus
100653516 Sus scrofa
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