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Dual Oxidase Maturation Factor 2 (DUOXA2) ELISA Kits

DUOXA2 encodes an endoplasmic reticulum protein that is necessary for proper cellular localization and maturation of functional dual oxidase 2. Additionally we are shipping DUOXA2 Antibodies (33) and DUOXA2 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human DUOXA2 DUOXA2 405753 Q1HG44
Anti-Mouse DUOXA2 DUOXA2 66811 Q9D311
Anti-Rat DUOXA2 DUOXA2 499879  
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More ELISA Kits for DUOXA2 Interaction Partners

Human Dual Oxidase Maturation Factor 2 (DUOXA2) interaction partners

  1. inactivating mutations in the DUOXA2 (p.Y246X) and DUOX2 (show DUOX2 ELISA Kits) (p.R885Q) genes were identified in a set of dizygotic twins with congenital hypothyroidism

  2. The folding of DUOX2 (show DUOX2 ELISA Kits) appears to be a key event in the trafficking of the DUOX2 (show DUOX2 ELISA Kits)/DUOXA2 complex as it promotes an appropriate conformation of the N-terminal region, which is propitious to subsequent covalent interactions with the maturation factor, DUOXA2.

  3. a novel DUOXA2 mutation (I26M) causing congenital hypothyroidism with goiter, which affected H2O2 generation but did not alter the protein expression levels, further confirming the essential role of DUOXA2 in thyroid hormone (show PTH ELISA Kits) synthesis.

  4. The DUOX (show DUOX1 ELISA Kits)-expressing model, the human intestinal Caco-2 cell line, expression of DUOXA2 mRNA was also positively modulated by IL-4 (show IL4 ELISA Kits) and IL-13 (show IL13 ELISA Kits).

  5. DUOXA2 is Significantly Upregulated in Active Ulcerative Colitis and during Progression to Dysplasia.

  6. This study is the first to report a novel c.413-414insA (Y138X) mutation for congenital hypothyroidism, thereby expanding the mutational spectrum of the DUOXA2 gene.

  7. Two functionally important single-nucleotide polymorphisms within the promoter differentially regulate DUOX2 (show DUOX2 ELISA Kits)/DUOXA2 transcription in response to exogenous double-stranded DNA.

  8. Native DUOXA2 would constrain DUOX2 (show DUOX2 ELISA Kits) to produce H(2)O(2).

  9. Up-regulation and sustained activation of Stat1 (show STAT1 ELISA Kits) are essential for interferon-gamma (IFN-gamma (show IFNG ELISA Kits))-induced (show SAMHD1 ELISA Kits) dual oxidase 2 (Duox2 (show DUOX2 ELISA Kits)) and dual oxidase (show DUOX1 ELISA Kits) A2 (DuoxA2) expression in human pancreatic cancer cell lines.

  10. co-expression of DUOXA2, an ER-resident transmembrane protein, allows ER-to-Golgi transition, maturation, and translocation to the plasma membrane of functional DUOX2 (show DUOX2 ELISA Kits) in a heterologous system

DUOXA2 Antigen Profile

Antigen Summary

This gene encodes an endoplasmic reticulum protein that is necessary for proper cellular localization and maturation of functional dual oxidase 2. Mutations in this gene have been associated with thyroid dyshormonogenesis 5.

Gene names and symbols associated with DUOXA2

  • dual oxidase maturation factor 1-like (DUOXA1L) antibody
  • dual oxidase maturation factor 2 (DUOXA2) antibody
  • dual oxidase maturation factor 2 (Duoxa2) antibody
  • 9030623N16Rik antibody
  • DUOXA1 antibody
  • DUOXA2 antibody
  • RGD1560628 antibody
  • SIMNIPHOM antibody
  • TDH5 antibody

Protein level used designations for DUOXA2

dual oxidase maturation factor 2 , dual oxidase maturation factor 2-like , Numb-interacting protein 2

427483 Gallus gallus
743164 Pan troglodytes
100379136 Ovis aries
405753 Homo sapiens
66811 Mus musculus
499879 Rattus norvegicus
609210 Canis lupus familiaris
514414 Bos taurus
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