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Dual Specificity Phosphatase 14 (DUSP14) ELISA Kits

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. Additionally we are shipping Dual Specificity Phosphatase 14 Antibodies (99) and Dual Specificity Phosphatase 14 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human DUSP14 DUSP14 11072 O95147
Anti-Mouse DUSP14 DUSP14 56405 Q9JLY7
Anti-Rat DUSP14 DUSP14 360580  
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More ELISA Kits for Dual Specificity Phosphatase 14 Interaction Partners

Human Dual Specificity Phosphatase 14 (DUSP14) interaction partners

  1. levels significantly decreased in failing hearts

  2. these findings reveal a novel mechanism by which TRAF2 (show TRAF2 ELISA Kits) mediates Lys63-linked ubiquitination of DUSP14, leading to DUSP14 activation in T cells

  3. findings suggest that DUSP14 negatively regulates TNF (show TNF ELISA Kits)- or IL-1 (show IL1A ELISA Kits)-induced NF-kappaB (show NFKB1 ELISA Kits) activation by dephosphorylating TAK1 (show MAP3K7 ELISA Kits) at Thr (show TRH ELISA Kits)-187

  4. DUSP14 may be a susceptibility gene for pulmonary tuberculosis.

  5. The overproduction, purification and crystal structure at 1.88 A resolution of human dual-specificity phosphatase 14, DUSP14 (MKP6), are reported.

  6. Activation of ATM (show ATM ELISA Kits) by radiation down-regulates phospho-ERK1/2 (show MAPK1/3 ELISA Kits) and its downstream signaling via increased expression of mitogen-activated protein kinase (show MAPK1 ELISA Kits) phosphatase MKP-1 (show DUSP1 ELISA Kits).

  7. The binding of Lipomannan to TLR2 (show TLR2 ELISA Kits) triggers MAPK (show MAPK1 ELISA Kits) activation, followed by an up-regulation of MKP-1 (show DUSP1 ELISA Kits) expression, which in turn may act as a negative regulator of MAPK (show MAPK1 ELISA Kits) activation.

Mouse (Murine) Dual Specificity Phosphatase 14 (DUSP14) interaction partners

  1. protects the heart from aortic banding-induced cardiac hypertrophy and dysfunction possibly through inactivation of TAK1 (show NR2C2 ELISA Kits)-P38MAPK (show MAPK14 ELISA Kits)/-JNK1 (show MAPK8 ELISA Kits)/2 signaling pathway

  2. DUSP14 negatively regulates TCR signaling and immune responses by inhibiting TAB1 (show TAB1 ELISA Kits) activation.

  3. dual specificity phosphatases (Dusps) 6 and 14 are up-regulated by activation of beta-catenin (show CTNNB1 ELISA Kits) in murine liver cells

  4. critical role for JNK1 (show MAPK8 ELISA Kits) in the regulation of Mkp1 (show DUSP1 ELISA Kits) induction and in LPS (show TLR4 ELISA Kits)-dependent macrophage activation.

  5. knockdown of CREMalpha or DUSP14 or expression of a dominant-negative form of DUSP14 increased beta-cell line proliferation and enhanced the GLP-1 (show GCG ELISA Kits)-induced proliferation of primary beta-cells

Dual Specificity Phosphatase 14 (DUSP14) Antigen Profile

Antigen Summary

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009

Gene names and symbols associated with DUSP14

  • dual specificity phosphatase 14 (DUSP14) antibody
  • dual specificity phosphatase 14 (dusp14) antibody
  • dual specificity phosphatase 14 (Dusp14) antibody
  • 1110014C10Rik antibody
  • 2310042C07Rik antibody
  • D11Ertd395e antibody
  • DUSP14 antibody
  • MGC84083 antibody
  • MKP-L antibody
  • Mkp6 antibody
  • zgc:101746 antibody

Protein level used designations for DUSP14

dual specificity phosphatase 14 , dual specificity protein phosphatase 14 , MAP kinase phosphatase 6 , MKP-1 like protein tyrosine phosphatase , MKP-1-like protein tyrosine phosphatase , MKP-6 , mitogen-activated protein kinase phosphatase 6 , MAP kinase phsophatase 6 , Mkp-1 like protein tyrosine phosphatase

GENE ID SPECIES
417657 Gallus gallus
444606 Xenopus laevis
450040 Danio rerio
468226 Pan troglodytes
491131 Canis lupus familiaris
714383 Macaca mulatta
779639 Xenopus (Silurana) tropicalis
11072 Homo sapiens
56405 Mus musculus
360580 Rattus norvegicus
507294 Bos taurus
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