Dual Specificity Phosphatase 14 Proteins (DUSP14)

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. Additionally we are shipping Dual Specificity Phosphatase 14 Antibodies (104) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DUSP14 11072 O95147
DUSP14 56405 Q9JLY7
Rat DUSP14 DUSP14 360580  
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Top Dual Specificity Phosphatase 14 Proteins at antibodies-online.com

Showing 6 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human MBP tag,His tag 100 μg Log in to see 20 to 21 Days
$437.80
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HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,480.50
Details

DUSP14 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , , ,
Mouse (Murine)

More Proteins for Dual Specificity Phosphatase 14 (DUSP14) Interaction Partners

Human Dual Specificity Phosphatase 14 (DUSP14) interaction partners

  1. The AA genotype was associated with protection against active TB. Among disease-free individuals, T-helper type-1 related genes, IFNGR2 (show IFNGR2 Proteins) and STAT1 (show STAT1 Proteins) mRNA levels significantly increased as the number of A alleles of rs1051838 increased.

  2. levels significantly decreased in failing hearts

  3. these findings reveal a novel mechanism by which TRAF2 (show TRAF2 Proteins) mediates Lys63-linked ubiquitination of DUSP14, leading to DUSP14 activation in T cells

  4. findings suggest that DUSP14 negatively regulates TNF (show TNF Proteins)- or IL-1 (show IL1A Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation by dephosphorylating TAK1 (show MAP3K7 Proteins) at Thr (show TRH Proteins)-187

  5. DUSP14 may be a susceptibility gene for pulmonary tuberculosis.

  6. The overproduction, purification and crystal structure at 1.88 A resolution of human dual-specificity phosphatase 14, DUSP14 (MKP6), are reported.

  7. Activation of ATM (show ATM Proteins) by radiation down-regulates phospho-ERK1/2 and its downstream signaling via increased expression of mitogen-activated protein kinase (show MAPK1 Proteins) phosphatase MKP-1 (show DUSP1 Proteins).

  8. The binding of Lipomannan to TLR2 triggers MAPK (show MAPK1 Proteins) activation, followed by an up-regulation of MKP-1 (show DUSP1 Proteins) expression, which in turn may act as a negative regulator of MAPK (show MAPK1 Proteins) activation.

Mouse (Murine) Dual Specificity Phosphatase 14 (DUSP14) interaction partners

  1. protects the heart from aortic banding-induced cardiac hypertrophy and dysfunction possibly through inactivation of TAK1 (show NR2C2 Proteins)-P38MAPK (show MAPK14 Proteins)/-JNK1 (show MAPK8 Proteins)/2 signaling pathway

  2. DUSP14 negatively regulates TCR signaling and immune responses by inhibiting TAB1 (show TAB1 Proteins) activation.

  3. dual specificity phosphatases (Dusps) 6 and 14 are up-regulated by activation of beta-catenin (show CTNNB1 Proteins) in murine liver cells

  4. critical role for JNK1 (show MAPK8 Proteins) in the regulation of Mkp1 (show DUSP1 Proteins) induction and in LPS (show TLR4 Proteins)-dependent macrophage activation.

  5. knockdown of CREMalpha or DUSP14 or expression of a dominant-negative form of DUSP14 increased beta-cell line proliferation and enhanced the GLP-1 (show GCG Proteins)-induced proliferation of primary beta-cells

Dual Specificity Phosphatase 14 (DUSP14) Protein Profile

Protein Summary

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009

Gene names and symbols associated with DUSP14

  • dual specificity phosphatase 14 (DUSP14)
  • dual specificity phosphatase 14 (dusp14)
  • dual specificity phosphatase 14 (Dusp14)
  • 1110014C10Rik protein
  • 2310042C07Rik protein
  • D11Ertd395e protein
  • DUSP14 protein
  • MGC84083 protein
  • MKP-L protein
  • Mkp6 protein
  • zgc:101746 protein

Protein level used designations for DUSP14

dual specificity phosphatase 14 , dual specificity protein phosphatase 14 , MAP kinase phosphatase 6 , MKP-1 like protein tyrosine phosphatase , MKP-1-like protein tyrosine phosphatase , MKP-6 , mitogen-activated protein kinase phosphatase 6 , MAP kinase phsophatase 6 , Mkp-1 like protein tyrosine phosphatase

GENE ID SPECIES
417657 Gallus gallus
444606 Xenopus laevis
450040 Danio rerio
468226 Pan troglodytes
491131 Canis lupus familiaris
714383 Macaca mulatta
779639 Xenopus (Silurana) tropicalis
11072 Homo sapiens
56405 Mus musculus
360580 Rattus norvegicus
507294 Bos taurus
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