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DYRK1B is a member of the DYRK family of protein kinases. Additionally we are shipping DYRK1B Proteins (5) and many more products for this protein.
Showing 10 out of 104 products:
Human Polyclonal DYRK1B Primary Antibody for EIA, WB - ABIN952008
Lauth, Bergström, Shimokawa, Tostar, Jin, Fendrich, Guerra, Barbacid, Toftgård: DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS. in Nature structural & molecular biology 2010
Show all 5 references for ABIN952008
Human Polyclonal DYRK1B Primary Antibody for IHC (p), WB - ABIN391774
Takahashi-Yanaga, Mori, Matsuzaki, Watanabe, Hirata, Miwa, Morimoto, Sasaguri: Involvement of GSK-3beta and DYRK1B in differentiation-inducing factor-3-induced phosphorylation of cyclin D1 in HeLa cells. in The Journal of biological chemistry 2006
Show all 4 references for ABIN391774
High DYRK1B expression is associated with pancreatic and skin cancers.
The study shows that DYRK1B is a novel ERK2 (show MAPK1 Antibodies) substrate, uncovering new links between two kinases involved in cell fate decisions.
Data reveal a novel role for miR (show MLXIP Antibodies)-9 in regulation of the NFAT (show NFATC1 Antibodies) pathway by targeting KPNB1 (show KPNB1 Antibodies) and DYRK1B.
NKX3.1 (show NKX3-1 Antibodies) and DYRK1B were shown to interact via the DYRK1B kinase domain. In vitro kinase assay showed that DYRK1B phosphorylated NKX3.1 (show NKX3-1 Antibodies) at serine 185, a residue critical for NKX3.1 (show NKX3-1 Antibodies) steady-state turnover.
Upregulation of Mirk mRNA expression is mediated by CREB (show CREB1 Antibodies) binding to two sites in the Mirk promoter upstream of the transcription start site and one site within exon 4.
A founder mutation was identified in DYRK1B, substituting cysteine for arginine at position 102 in 3 families with metabolic syndrome.
DYRK1B is a novel Thr (show TRH Antibodies)(286)-CCND1 (show CCND1 Antibodies) kinase that acts independently of GSK3beta (show GSK3b Antibodies) to promote CCND1 (show CCND1 Antibodies) degradation.
Mirk/Dyrk1B plays an important role in ovarian cancer cell survival through modulating FoxO (show FOXO3 Antibodies) translocation.
In line with a redirection of autocrine toward paracrine HH signaling by a KRAS-DYRK1B network, we find high levels of GLI1 (show GLI1 Antibodies) expression restricted to the stromal compartment and not to SHH (show SHH Antibodies)-expressing tumor cells in pancreatic adenocarcinoma.
the kinase Mirk is essential for the growth and survival of osteosarcoma cells.
results suggest that functional interactions between BM88/Cend1 (show CEND1 Antibodies), RanBPM (show RANBP9 Antibodies) and Dyrk1B affect the balance between cellular proliferation and differentiation in Neuro 2a cells
Cirp (show CIRBP Antibodies) functions to fine-tune the proliferation of undifferentiated spermatogonia by interacting with Dyrk1b.
p38 MAP Kinase (show MAPK14 Antibodies) suppresses the function of Mirk as a transcriptional activator only when cells are proliferating
dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation
p27Kip1 (show CDKN1B Antibodies) is stabilized in G(0) by Mirk/dyrk1B kinase
Mirk may function together with GSK3beta (show GSK3b Antibodies) to assist cell arrest by destabilizing cyclin D1 (show CCND1 Antibodies).
Mirk is induced within the initial 24 h of myogenic differentiation and enables MEF2 (show MEF2C Antibodies) to transcribe the myogenin (show MYOG Antibodies) gene by decreasing the nuclear accumulation of class II HDACs
Mirk is anti-apoptotic in myoblasts
BCL2 (show BCL2 Antibodies) and BCL-xL (show BCL2L1 Antibodies) facilitation of G0 quiescence requires BAX (show BAX Antibodies), BAK (show BAK1 Antibodies), and p27 (show CDKN1B Antibodies) phosphorylation by Mirk
DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain.
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
, dual specificity tyrosine-phosphorylation-regulated kinase 1B-like
, dual specificity tyrosine-phosphorylation-regulated kinase 1B
, minibrain-related kinase
, mirk protein kinase
, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A