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Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B Proteins (DYRK1B)

DYRK1B is a member of the DYRK family of protein kinases. Additionally we are shipping DYRK1B Antibodies (100) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DYRK1B 9149 Q9Y463
DYRK1B 13549 Q9Z188
Rat DYRK1B DYRK1B 308468  
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Top DYRK1B Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days

DYRK1B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

More Proteins for Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) Interaction Partners

Human Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) interaction partners

  1. The study shows that DYRK1B is a novel ERK2 (show MAPK1 Proteins) substrate, uncovering new links between two kinases involved in cell fate decisions.

  2. Data reveal a novel role for miR (show MLXIP Proteins)-9 in regulation of the NFAT (show NFATC1 Proteins) pathway by targeting KPNB1 (show KPNB1 Proteins) and DYRK1B.

  3. NKX3.1 (show NKX3-1 Proteins) and DYRK1B were shown to interact via the DYRK1B kinase domain. In vitro kinase assay showed that DYRK1B phosphorylated NKX3.1 (show NKX3-1 Proteins) at serine 185, a residue critical for NKX3.1 (show NKX3-1 Proteins) steady-state turnover.

  4. Upregulation of Mirk mRNA expression is mediated by CREB (show CREB1 Proteins) binding to two sites in the Mirk promoter upstream of the transcription start site and one site within exon 4.

  5. A founder mutation was identified in DYRK1B, substituting cysteine for arginine at position 102 in 3 families with metabolic syndrome.

  6. DYRK1B is a novel Thr (show TRH Proteins)(286)-CCND1 (show CCND1 Proteins) kinase that acts independently of GSK3beta to promote CCND1 (show CCND1 Proteins) degradation.

  7. Mirk/Dyrk1B plays an important role in ovarian cancer cell survival through modulating FoxO (show FOXO3 Proteins) translocation.

  8. In line with a redirection of autocrine toward paracrine HH signaling by a KRAS-DYRK1B network, we find high levels of GLI1 (show GLI1 Proteins) expression restricted to the stromal compartment and not to SHH (show SHH Proteins)-expressing tumor cells in pancreatic adenocarcinoma.

  9. the kinase Mirk is essential for the growth and survival of osteosarcoma cells.

  10. activation by MKK2 (show MAP2K2 Proteins) and role as transcriptional activator of HNF1alpha (show HNF1A Proteins)

Mouse (Murine) Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) interaction partners

  1. results suggest that functional interactions between BM88/Cend1 (show CEND1 Proteins), RanBPM (show RANBP9 Proteins) and Dyrk1B affect the balance between cellular proliferation and differentiation in Neuro 2a cells

  2. Cirp (show CIRBP Proteins) functions to fine-tune the proliferation of undifferentiated spermatogonia by interacting with Dyrk1b.

  3. p38 MAP Kinase (show MAPK14 Proteins) suppresses the function of Mirk as a transcriptional activator only when cells are proliferating

  4. dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation

  5. p27Kip1 (show CDKN1B Proteins) is stabilized in G(0) by Mirk/dyrk1B kinase

  6. Mirk may function together with GSK3beta to assist cell arrest by destabilizing cyclin D1 (show CCND1 Proteins).

  7. Mirk is induced within the initial 24 h of myogenic differentiation and enables MEF2 (show MEF2C Proteins) to transcribe the myogenin (show MYOG Proteins) gene by decreasing the nuclear accumulation of class II HDACs

  8. Mirk is anti-apoptotic in myoblasts

  9. BCL2 (show BCL2 Proteins) and BCL-xL (show BCL2L1 Proteins) facilitation of G0 quiescence requires BAX (show BAX Proteins), BAK (show BAK1 Proteins), and p27 (show CDKN1B Proteins) phosphorylation by Mirk

DYRK1B Protein Profile

Protein Summary

DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain.

Gene names and symbols associated with DYRK1B

  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B (DYRK1B)
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b)
  • DYRK1A protein
  • DYRK1B protein
  • Mirk protein

Protein level used designations for DYRK1B

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B , dual specificity tyrosine-phosphorylation-regulated kinase 1B-like , dual specificity tyrosine-phosphorylation-regulated kinase 1B , minibrain-related kinase , mirk protein kinase , dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

456030 Pan troglodytes
100012195 Monodelphis domestica
100344122 Oryctolagus cuniculus
100439443 Pongo abelii
100469690 Ailuropoda melanoleuca
9149 Homo sapiens
13549 Mus musculus
308468 Rattus norvegicus
484506 Canis lupus familiaris
100625631 Sus scrofa
507571 Bos taurus
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