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anti-Dynactin 2 (p50) (DCTN2) Antibodies

DCTN2 encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Additionally we are shipping Dynamitin Proteins (11) and Dynamitin Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCTN2 69654 Q99KJ8
DCTN2 10540 Q13561
DCTN2 299850 Q6AYH5
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Top anti-Dynamitin Antibodies at antibodies-online.com

Showing 10 out of 72 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-DCTN2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB DCTN2 Antibody (Center) (ABIN656819) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed and paraffin embedded human stomach tissue stained with  Dynactin subunit 2  Antibody  followed by peroxidase conjugation of the secondary antibody and DAB staining Western blot analysis of DCTN2 (arrow) using Dynactin subunit 2 Antibody . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DCTN2 gene. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to DCTN2 on MCF-7 cell (antibody concentration 10 µg/mL). DCTN2 monoclonal antibody (M01), clone 2G7 Western Blot analysis of DCTN2 expression in MCF-7. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from A549 cells, using p50 Dynamitin Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of DCTN2 expression in transfected 293T cell line by DCTN2 MaxPab polyclonal antibody.Lane 1: DCTN2 transfected lysate(44.11 KDa).Lane 2: Non-transfected lysate. DCTN2 MaxPab polyclonal antibody. Western Blot analysis of DCTN2 expression in human spleen. 50 μg Log in to see 9 Days
$430.00
Details

DCTN2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Dynamitin Antibodies

  1. Human Polyclonal Dynamitin Primary Antibody for EIA, IHC (p) - ABIN952005 : Jacquot, Maidou-Peindara, Benichou: Molecular and functional basis for the scaffolding role of the p50/dynamitin subunit of the microtubule-associated dynactin complex. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN952005

  2. Human Monoclonal Dynamitin Primary Antibody for IF, WB - ABIN393305 : Pridgeon, Webber, Sha, Li, Chin: Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes. in The FEBS journal 2008 (PubMed)
    Show all 5 references for ABIN393305

  3. Human Polyclonal Dynamitin Primary Antibody for IF, WB - ABIN523956 : Chatin, Colombier, Gamblin, Allouis, Le Bouffant: Dynamitin affects cell-surface expression of voltage-gated sodium channel Nav1.5. in The Biochemical journal 2014 (PubMed)

  4. Chicken Polyclonal Dynamitin Primary Antibody for WB - ABIN2787686 : Camargo, Collura, Rain, Mizuguchi, Hermjakob, Kerrien, Bonnert, Whiting, Brandon: Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. in Molecular psychiatry 2006 (PubMed)

More Antibodies against Dynamitin Interaction Partners

Fruit Fly (Drosophila melanogaster) Dynactin 2 (p50) (DCTN2) interaction partners

  1. Our results suggest a model whereby endocytic activity recruits Dynein to the oocyte cortex. The motor along with its regulators, Dynactin (show DCTN1 Antibodies) and Lis1 (show PAFAH1B1 Antibodies), functions to ensure efficient endocytic uptake and maturation.

Mouse (Murine) Dynactin 2 (p50) (DCTN2) interaction partners

  1. Altered levels of Cep135 (show CEP135 Antibodies) and p50 (show LSP1 Antibodies) by RNAi and protein overexpression caused the release of endogenous partner molecules from centrosomes.

Human Dynactin 2 (p50) (DCTN2) interaction partners

  1. dynamitin is involved in the regulation of Nav1.5 (show SCN5A Antibodies) cell-surface density

  2. the determinants of p50 (show CD40 Antibodies)/DM required for self-oligomerization of the protein and for interactions with other subunits of the dynactin (show DCTN1 Antibodies) complex

  3. Altered levels of Cep135 (show CEP135 Antibodies) and p50 (show CD40 Antibodies) by RNAi and protein overexpression caused the release of endogenous partner molecules from centrosomes.

  4. the Sec23p component of the COPII complex directly interacts with the dynactin (show DCTN1 Antibodies) complex through the carboxy-terminal cargo-binding domain of p150(Glued (show DCTN1 Antibodies)).

  5. DCTN2 is required in the earliest stages of peroxisome biogenesis.

  6. study does not support a major role for DCTN2 overexpression in carcinogenesis

  7. Data show how dynamitin's different structural domains contribute to its ability to self-associate, interact with dynactin (show DCTN1 Antibodies) and assemble into a complex with its close binding partner, p24.

  8. The interaction between ZW10 (show ZW10 Antibodies) and dynamitin showed that the N-terminal region of ZW10 (show ZW10 Antibodies) is the major binding site for dynamitin and, like full-length ZW10 (show ZW10 Antibodies), could move along microtubules to the centrosomal area in a dynein-dynactin (show DCTN1 Antibodies)-dependent manner.

Zebrafish Dynactin 2 (p50) (DCTN2) interaction partners

  1. These results indicate that the p50 (show ARHGEF7 Antibodies) component of the dynactin (show DCTN1 Antibodies) complex is essential for the survival of sensory neurons and the maintenance of ganglion cell axons, and functions as a major determinant of apicobasal polarity in retinal radial glia.

Dynamitin (DCTN2) Antigen Profile

Protein Summary

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with DCTN2

  • dynactin 2 (p50) (DCTN2) antibody
  • dynactin 2 (p50) (dctn2-b) antibody
  • Dynamitin (Dmn) antibody
  • dynactin 2 (p50) (dctn2) antibody
  • dynactin 2 (Dctn2) antibody
  • dynactin 2 (p50) (Dctn2) antibody
  • dynactin 2 (p50) (dctn2-a) antibody
  • 2310042E05Rik antibody
  • C87049 antibody
  • C130077D06Rik antibody
  • CG8269 antibody
  • DCTN-50 antibody
  • dctn2 antibody
  • DCTN50 antibody
  • dDyn antibody
  • Dmel\\CG8269 antibody
  • dmn antibody
  • dyna antibody
  • DYNAMITIN antibody
  • GMP23-48K antibody
  • l(2)k16109 antibody
  • l(2)k16218 antibody
  • p50 antibody
  • p50/Dmn antibody
  • p50/dynamitin antibody
  • RBP50 antibody
  • zgc:63867 antibody

Protein level used designations for DCTN2

dynactin 2 (p50) , dynactin subunit 2 , dynactin subunit 2-B , dynamitin , CG8269-PA , Dmn-PA , p50-dynamitin , p50 dynamitin , p50/Dynamitin , 50 kDa dynein-associated polypeptide , dynactin complex 50 kDa subunit , growth cone membrane protein 23-48K , 50 kD dynein-associated polypeptide , dynactin complex 50 kD subunit , p50/dynamitin , dynactin subunit 2-A

GENE ID SPECIES
100050464 Equus caballus
100171591 Pongo abelii
380299 Xenopus laevis
44086 Drosophila melanogaster
548423 Xenopus (Silurana) tropicalis
714948 Macaca mulatta
100339187 Oryctolagus cuniculus
100615725 Pan troglodytes
69654 Mus musculus
10540 Homo sapiens
299850 Rattus norvegicus
394141 Danio rerio
447510 Xenopus laevis
395587 Gallus gallus
474415 Canis lupus familiaris
527201 Bos taurus
Selected quality suppliers for anti-Dynamitin (DCTN2) Antibodies
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