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Dctn3 encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Additionally we are shipping Dynactin 3 (p22) Proteins (6) and many more products for this protein.
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Human Polyclonal Dctn3 Primary Antibody for ELISA, WB - ABIN4304537
Abba, Sun, Hawkins, Drake, Hu, Nunez, Gaddis, Shi, Horvath, Sahin, Aldaz: Breast cancer molecular signatures as determined by SAGE: correlation with lymph node status. in Molecular cancer research : MCR 2007
This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants.
dynactin subunit 3
, dynactin 3 (p22)
, dynactin light chain (P24)
, dynactin light chain p24
, p24 dynactin light chain
, dynactin complex subunit 22 kDa subunit
, dynactin light chain