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Dynamin 1 Proteins (DNM1)

DNM1 encodes a member of the dynamin subfamily of GTP-binding proteins. Additionally we are shipping Dynamin 1 Antibodies (114) and Dynamin 1 Kits (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DNM1 1759 Q05193
DNM1 13429 P39053
Rat DNM1 DNM1 140694 P21575
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Top Dynamin 1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$753.50
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$936.27
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DNM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)
,

More Proteins for Dynamin 1 (DNM1) Interaction Partners

Horse (Equine) Dynamin 1 (DNM1) interaction partners

  1. Equine herpesvirus type 1 pUL56-induced MHC-I endocytosis required dynamin and tyrosine kinase but was independent of clathrin and caveolin-1, the main constituents of the clathrin- and raft/caveola-mediated endocytosis pathways, respectively.

Human Dynamin 1 (DNM1) interaction partners

  1. Hypoxic down-regulation of constitutive endocytosis is HIF-independent, and involves caveolin-1 (show CAV1 Proteins)-mediated inhibition of dynamin-dependent, membrane raft endocytosis.

  2. study reports 2 patients with early onset epileptic encephalopathy possessing de novo DNM1 mutations; detected the novel mutation c.127G>A (p.Gly43Ser) in a patient with Lennox-Gastaut syndrome, and a recurrent mutation c.709C>T (p.Arg237Trp) in a patient with West syndrome

  3. The rare variants in DNM1 were significantly associated with smoking status.

  4. Data indicate that stimulation of the dynamin GTPase activity by SH3 domains is determined by its middle domain.

  5. molecular simulations corroborate the bimodal character of dynamin action and indicate radial and axial forces as dominant, although not independent, drivers of hemi-fission and fission membrane- transformations, respectively

  6. Data indicate the dynamics of a dynamin 1-catalysed GTP (show AK3 Proteins) hydrolysis and tube-severing reaction in real time using fluorescence microscopy.

  7. This study identified and confirmed DNM1 protein changes within the postsynaptic density in schizophrenia.

  8. findings support a role for HTT (show HTT Proteins) on dynamin 1 function and ER homoeostasis. Proteolysis-induced alteration of this function may be relevant to disease.

  9. CRISPR-Cas9n-mediated knockout and reconstitution studies establish that dynamin-1 is activated by Akt/GSK3beta signaling in H1299 non-small lung cancer cells.

  10. Data suggest that by binding to both clathrin and F-actin, mammalian actin-binding protein 1 (mAbp1 (show DBNL Proteins); HIP-55 (show DBNL Proteins) or SH3P7 (show DBNL Proteins)) is specifically recruited at a late stage of clathrin-coated pits (CCPs) formation, which subsequently recruits dynamin to CCPs.

Mouse (Murine) Dynamin 1 (DNM1) interaction partners

  1. findings support a role for HTT (show HTT Proteins) on dynamin 1 function and ER homoeostasis. Proteolysis-induced alteration of this function may be relevant to disease.

  2. the identification of the oligomerization cycle of dynamin is an attractive potential therapeutic target to treat chronic kidney diseases .

  3. In the developing neurons, there is a dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis.

  4. Using an inducible knockout mouse model to generate dynamin 1- and 2-deficient primary osteoclast precursors and myoblasts, it was shown that fusion of both cell types requires dynamin.

  5. Dynamin 1 is required for memory formation.

  6. As low-level expression of the dynamin 3 (show DNM3 Proteins) gene in these cells could not be excluded, we have now engineered dynamin 1, 2 and 3 triple KO (TKO (show MRPS12 Proteins)) fibroblasts.

  7. Results further implicate dynamin-1 in vesicular protein transport processes relevant to synaptic and post-Golgi pathways and indicate a possible role in photoreceptor stability

  8. Data indicate that coxsackievirus and adenovirus receptor (show CXADR Proteins) (CAR) internalization was lipid microdomain-, actin-, and dynamin-dependent, and subsequently followed by CAR degradation in lysosomes.

  9. A missense mutation of dynamin 1 inhibits endocytosis via clathrin-mediated endocytosis.

  10. Data indicate that dynamin, clathrin, adaptor protein complex-2 (AP2 (show TFAP2A Proteins)), and amphiphysin (show AMPH Proteins) contribute to the depolarization-evoked entry in endocytosis.

Dynamin 1 (DNM1) Protein Profile

Protein Summary

This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with Dynamin 1 Proteins (DNM1)

  • dynamin-1 (BACOIKO008_37)
  • dynamin-1 (PTRG_07818)
  • dynamin-1 (PTRG_08097)
  • dynamin 1 (dnm1)
  • dynamin 1 (DNM1)
  • dynamin 1 (Dnm1)
  • dynamin-1-like (LOC100199205)
  • dynamin 1a (dnm1a)
  • dynamin-1-like protein (EHI_013180)
  • dynamin-1-like protein (EHI_131670)
  • dynamin 1-like (DNM1L)
  • AI838169 protein
  • Dnm protein
  • dnm1 protein
  • Ftfl protein
  • mKIAA4093 protein
  • si:dkey-246l19.2 protein

Protein level used designations for Dynamin 1 Proteins (DNM1)

dynamin-1 , dynamin 1 , dynamin-1-like , dynamin-1-like protein , B-dynamin , D100 , dynamin, brain , dynamin-1-like protein-like

GENE ID SPECIES
6166902 Oikopleura dioica
6346092 Pyrenophora tritici-repentis Pt-1C-BFP
6346375 Pyrenophora tritici-repentis Pt-1C-BFP
448130 Xenopus (Silurana) tropicalis
464766 Pan troglodytes
717697 Macaca mulatta
100070282 Equus caballus
100168088 Acyrthosiphon pisum
100199205 Hydra magnipapillata
100307098 Danio rerio
100388870 Callithrix jacchus
100470165 Ailuropoda melanoleuca
100544930 Meleagris gallopavo
100556614 Anolis carolinensis
100599465 Nomascus leucogenys
3403947 Entamoeba histolytica HM-1:IMSS
6220562 Entamoeba histolytica HM-1:IMSS
1759 Homo sapiens
13429 Mus musculus
140694 Rattus norvegicus
417217 Gallus gallus
508794 Bos taurus
491319 Canis lupus familiaris
100725033 Cavia porcellus
101108737 Ovis aries
100624497 Sus scrofa
477649 Canis lupus familiaris
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