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Dynein, Axonemal, Intermediate Chain 1 Proteins (DNAI1)

The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. Additionally we are shipping Dynein, Axonemal, Intermediate Chain 1 Antibodies (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DNAI1 27019 Q9UI46
DNAI1 68922 Q8C0M8
Rat DNAI1 DNAI1 500442 Q5XIL8
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Top Dynein, Axonemal, Intermediate Chain 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DNAI1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Dynein, Axonemal, Intermediate Chain 1 (DNAI1) Interaction Partners

Human Dynein, Axonemal, Intermediate Chain 1 (DNAI1) interaction partners

  1. The worldwide involvement of DNAI1 mutations in PCD pathogenesis in families not preselected for ODA defects ranges from 7 to 10%.

  2. A total of 10% of patients with PCD are estimated to harbor mutations in DNAI1; most occur as a common founder IVS1+2_3insT or in exons 13, 16, and 17.

  3. DNAI1 gene mutation is not a common cause of primary ciliary dyskinesia.

  4. Two dynein genes, encoding ODA intermediate chain (DNAI1) and heavy chain (DNAH5), have been seen to be mutated in approximately 30-38% of the families

Mouse (Murine) Dynein, Axonemal, Intermediate Chain 1 (DNAI1) interaction partners

  1. Dnah6 genetically interacts with Dnai1 and Dnah5 to cause heterotaxy and primary ciliary dyskinesia.

  2. Motile nodal cilia patterns heart looping but heart and visceral organ lateralization is driven by signaling not requiring nodal cilia motility. Dnaic1 mutants can achieve situs solitus or inversus even with immotile nodal cilia.

  3. dnaic1 deletion in a murine model of primary ciliary dyskinesia causes chronic rhinosinusitis

Dynein, Axonemal, Intermediate Chain 1 (DNAI1) Protein Profile

Protein Summary

The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome.

Gene names and symbols associated with DNAI1

  • dynein, axonemal, intermediate chain 1 (DNAI1)
  • dynein, axonemal, intermediate chain 1 (Dnaic1)
  • dynein, axonemal, intermediate chain 1 (Dnai1)
  • 1110066F04Rik protein
  • b2b1526Clo protein
  • BB124644 protein
  • CILD1 protein
  • DIC1 protein
  • Dnai1 protein
  • Dnaic1 protein
  • ICS1 protein
  • PCD protein

Protein level used designations for DNAI1

dynein, axonemal, intermediate chain 1 , dynein intermediate chain 1, axonemal-like , dynein intermediate chain 1, axonemal , dynein, axonemal, intermediate polypeptide 1 , immotile cilia syndrome 1 , axonemal dynein intermediate chain 1

GENE ID SPECIES
100393712 Callithrix jacchus
431654 Gallus gallus
27019 Homo sapiens
68922 Mus musculus
500442 Rattus norvegicus
524709 Bos taurus
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