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anti-Dynein, Light Chain, LC8-Type 1 (DYNLL1) Antibodies

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. Additionally we are shipping Dynein, Light Chain, LC8-Type 1 Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DYNLL1 50768 Q9R0Z9
DYNLL1 58834  
DYNLL1 9940 Q9Y238
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Top anti-Dynein, Light Chain, LC8-Type 1 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-DYNLL1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-DYNLL1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (f), IF, IP, WB Western blot analysis of PIN on a rat cerebrum lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the anti- PIN antibody. Immunofluorescence staining of rat neurons. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Rat Mouse Un-conjugated IF, WB Western blot analysis of PIN on a rat cerebrum lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the anti- PIN antibody. Immunofluorescence staining of rat neurons. 150 μg Log in to see 5 to 6 Days
$398.54
Details
Human Rabbit Un-conjugated IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rat Un-conjugated FACS, WB   100 μg Log in to see 11 to 16 Days
$629.93
Details

DYNLL1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Top referenced anti-Dynein, Light Chain, LC8-Type 1 Antibodies

  1. Human Monoclonal DYNLL1 Primary Antibody for IHC (f), IF - ABIN968140 : Dick, Ray, Salz, Chia: Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster. in Molecular and cellular biology 1996 (PubMed)
    Show all 2 references for ABIN968140

  2. Rat (Rattus) Monoclonal DYNLL1 Primary Antibody for IF, WB - ABIN968141 : Jaffrey, Snyder: PIN: an associated protein inhibitor of neuronal nitric oxide synthase. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 2 references for ABIN968141

  3. Chicken Polyclonal DYNLL1 Primary Antibody for WB - ABIN2784529 : Song, Wen, Rayala, Chen, Ma, Zhang, Kumar: Serine 88 phosphorylation of the 8-kDa dynein light chain 1 is a molecular switch for its dimerization status and functions. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against Dynein, Light Chain, LC8-Type 1 Interaction Partners

Pig (Porcine) Dynein, Light Chain, LC8-Type 1 (DYNLL1) interaction partners

  1. Large dynein heads take 16-nm steps by using an overlapping hand-over-hand mechanism.

Cow (Bovine) Dynein, Light Chain, LC8-Type 1 (DYNLL1) interaction partners

  1. LC8 promotes assembly and stabilization of microtubules.

  2. By yeast two-hybrid assay, the authors found that the capsid protein (CA) of bovine immunodeficiency virus interacted with the dynein light-chain component LC8.

Mouse (Murine) Dynein, Light Chain, LC8-Type 1 (DYNLL1) interaction partners

  1. studies demonstrate that TNS1 (show TNS1 Antibodies) binds to DLC1 (show DLC1 Antibodies) and fine-tunes its RhoGAP (show ARHGAP1 Antibodies) activity toward RhoA (show RHOA Antibodies) and that the TNS1 (show TNS1 Antibodies)-DLC1 (show DLC1 Antibodies)-RhoA (show RHOA Antibodies) signaling axis is critical in regulating cellular functions that lead to angiogenesis

  2. These findings uncovered the surprising functional relevance of GTP-bound Arl3 and LC8 for the unloading regulation of dynactin-bound cargo from dynein motor.

  3. Loss of expression of only Dlc1 (show DLC1 Antibodies) isoform 2 may be sufficient for the development of thymic tumors and metastasis.

  4. Several genes and biochemical activities collaborate with the inactivation of DLC1 (show DLC1 Antibodies) to give rise to cell transformation in MEFs, and the identified genes are relevant to human tumors with low DLC1 (show DLC1 Antibodies) expression.

  5. a key role for ASCIZ (show ATMIN Antibodies) in regulating the survival of developing B cells by activating DYNLL1 expression, which may then modulate Bim (show BCL2L11 Antibodies)-dependent apoptosis

  6. The ASCIZ (show ATMIN Antibodies)-DYNLL1 feedback loop represents a novel mechanism for auto-regulation of gene expression, where the gene product directly inhibits the transcriptional activator while bound at its own promoter.

  7. The Dlc1 (show DLC1 Antibodies) deficient cells showed altered cytoskeleton structure, increased RhoA (show RHOA Antibodies) activity and cellular migration.

  8. DLC-1 (show DLC1 Antibodies)-/- embryos had defects in the neural tube, brain, heart, and placenta

  9. Our data validate DLC1 (show DLC1 Antibodies) as a potent tumor suppressor gene and suggest that its loss creates a dependence on the RhoA (show RHOA Antibodies) pathway that may be targeted therapeutically.

  10. the regulation of DLC1 (show DLC1 Antibodies) by p21-activated kinase 1 (show PAK1 Antibodies) is a novel mechanism by which a signaling kinase might influence macropinocytosis

Human Dynein, Light Chain, LC8-Type 1 (DYNLL1) interaction partners

  1. DLC1 binding to nNOS (show NOS1 Antibodies)-calmodulin (show CALM1 Antibodies) complex does not affect the electron transport from the reductase to the oxygenase domain.

  2. NMR-derived secondary chemical shifts and relaxation properties show that the Chica (show FAM83D Antibodies) LC8 binding domain is essentially disordered with a dynamically restricted segment in one linker between motifs.

  3. DLEC1 (show DLEC1 Antibodies) mediates tumor-suppressive activities through NF-kappaB (show NFKB1 Antibodies) signaling.

  4. Studies indicate that dynein light chain LC8 has been termed an intrinsically disordered proteins (IDPs) dimerization 'hub' protein.

  5. DLC1 binding motif in L is involved in cytoskeleton localization and reorganization, primary transcription regulation by DLC1, and regulation of cellular DLC1 gene expression.

  6. DLEC1 (show DLEC1 Antibodies) methylation was not associated with the clinicopathological variables of gastric cancer.

  7. The dynein light intermediate chain has a Ras-like fold with insertions that distinguish it from Ras and other previously described G proteins.

  8. DLEC1 (show DLEC1 Antibodies) is down-regulated in head and neck squamous cell tumors and it's promoter methylation is not associated with the clinicopathological parameters.

  9. Authors demonstrate that the interaction between ebola virus VP35 and dynein LC8 is direct and of high affinity and that binding stabilizes the VP35 N-terminal oligomerization domain and enhances viral RNA synthesis.

  10. Overall, this study demonstrates the novel interaction between HIV-1 integrase and cellular DYNLL1 proteins and suggests the requirement of this virus-cell interaction for proper uncoating and efficient reverse transcription of HIV-1.

Caenorhabditis elegans (C. elegans) Dynein, Light Chain, LC8-Type 1 (DYNLL1) interaction partners

  1. DLC-1 is functioning cell nonautonomously through the same pathway as kri-1 (show KRI1 Antibodies) in response to ionizing radiation-induced apoptosis.

  2. Dynein light chain 1 (DLC-1) and its partner, dynein heavy chain 1, inhibit the proliferative cell fate, in part through regulation of METT-10, a conserved putative methyltransferase.

Dynein, Light Chain, LC8-Type 1 (DYNLL1) Antigen Profile

Protein Summary

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.

Gene names and symbols associated with DYNLL1

  • dynein, light chain, LC8-type 1 (dynll1-a) antibody
  • dynein, light chain, LC8-type 1 (dynll1) antibody
  • dynein, light chain, LC8-type 1 (DYNLL1) antibody
  • deleted in liver cancer 1 (dlc1) antibody
  • deleted in liver cancer 1 (DLC1) antibody
  • deleted in liver cancer 1 (Dlc1) antibody
  • deleted in lung and esophageal cancer 1 (DLEC1) antibody
  • dynein light chain LC8-type 1 (Dynll1) antibody
  • dynein, light chain, LC8-type 1 (dynll1-b) antibody
  • dynein, light chain, LC8-type 1 (LOC770215) antibody
  • Protein DLC-1 (dlc-1) antibody
  • 8kDLC antibody
  • A730069N07Rik antibody
  • Arhgap7 antibody
  • CDLC2 antibody
  • dlc-1 antibody
  • DLC1 antibody
  • DLC8 antibody
  • DNCL1 antibody
  • DNCLC1 antibody
  • DYNLL1 antibody
  • dynll1a antibody
  • dynll1b antibody
  • dynll2 antibody
  • F56 antibody
  • hdlc1 antibody
  • HP antibody
  • LC8 antibody
  • LC8a antibody
  • MGC68763 antibody
  • MGC89636 antibody
  • PIN antibody
  • RhoGAP antibody
  • rhogap7 antibody
  • StARD12 antibody
  • wu:fd56c09 antibody
  • zgc:73406 antibody

Protein level used designations for DYNLL1

dynein, light chain, LC8-type 1 , dynein, light chain, LC8-type 1a , cytoplasmic light-chain dynein , dynein light chain 1, cytoplasmic , Deleted in liver cancer 1 protein homolog , Rho-type GTPase-activating protein 7 , START domain-containing protein 12 , rho GTPase-activating protein 7 , stAR-related lipid transfer protein 12 , deleted in liver cancer 1 protein homolog , rho-type GTPase-activating protein 7 , p122-RhoGAP , dlc-1 , rho GTPase activating protein 7 , stARD12 , DLC-1 , deleted in lung and esophageal cancer 1 transcript varient 2 , deleted in lung and esophageal cancer protein 1 , 8 kDa dynein light chain , 8kD LC , 8kDa LC , dynein, cytoplasmic, light chain 1 , dynein, cytoplasmic, light peptide , mPIN , protein inhibitor of neuronal nitric oxide synthase , protein inhibitor of nitric oxide synthase , dynein LC8 , cytoplasmic dynein light polypeptide , dynein, cytoplasmic, light polypeptide 1 , dynein, light chain, LC8-type 1b , dynein light chain LC8-type 1 , DLC8 , dynein light chain 2 , dynein, light chain, LC8-type 2

GENE ID SPECIES
379617 Xenopus laevis
448652 Xenopus (Silurana) tropicalis
742676 Pan troglodytes
100157773 Sus scrofa
431800 Xenopus laevis
475607 Canis lupus familiaris
511433 Bos taurus
50768 Mus musculus
58834 Rattus norvegicus
9940 Homo sapiens
56455 Mus musculus
58945 Rattus norvegicus
8655 Homo sapiens
444051 Xenopus laevis
770215 Gallus gallus
404151 Bos taurus
100008650 Oryctolagus cuniculus
406297 Danio rerio
175922 Caenorhabditis elegans
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