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Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Additionally we are shipping DYNLL2 Antibodies (22) and many more products for this protein.
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Human DYNLL2 Protein expressed in Escherichia coli (E. coli) - ABIN667470
Lu, Sun, Chen, Wang, Hu, Gu: Identification of dynein light chain 2 as an interaction partner of p21-activated kinase 1. in Biochemical and biophysical research communications 2005
Show all 2 references for ABIN667470
GKAP (show DLGAP1 Proteins)-DLC2 interaction organizes the postsynaptic scaffold complex to enhance synaptic NMDA receptor activity.
DLC2-mutant mice display enhanced angiogenic responses.
These data show that alternative splicing of the myosin Va (show MYO5A Proteins) heavy chain controls DYNLL2-myosin Va (show MYO5A Proteins) interaction and that DYNLL2 binding alters the structure of a portion of the myosin's coiled-coil domain.
The DYNLL2 binding region, located in an intrinsically disordered domain of the myo5a (show MYO5A Proteins) tail, has a nascent helical character.
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).
dynein light chain 1, cytoplasmic
, dynein light chain 2
, dynein, light chain, LC8-type 2
, dynein light chain 2, cytoplasmic
, 8 kDa dynein light chain b
, dynein light chain-2
, radial spoke 22 homolog
, dynein light chain LC8-type 2