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Dystonin Proteins (DST)

DST encodes a member of the plakin protein family of adhesion junction plaque proteins. Additionally we are shipping Dystonin Antibodies (18) and Dystonin Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DST 667 Q03001
Mouse DST DST 13518  
Rat DST DST 316313  
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Top Dystonin Proteins at

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days

DST Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Dystonin (DST) Interaction Partners

Human Dystonin (DST) interaction partners

  1. Two of the six genes (LAMA3 (show LAMA3 Proteins) and DST) validated by quantitative RT-PCR for tumor-specific alternative splicing events

  2. Results identify four families with autosomal recessive EBS from Kuwait in whom the skin fragility is caused by recurrent nonsense mutation in DST-4.

  3. Circulating anti-BP230 autoantibodies are not correlated with severity of genital lichen sclerosis or itching.

  4. A key role for BPAG1-e in regulating keratinocyte adhesion and migration and suggest a requirement for this protein in controlling functional switching between integrin types in epithelial cells.

  5. Authors conclude that, during entry of herpes simplex virus 1, dystonin has a specific role in plus-ended transport of capsids from the centrosome to the nucleus.

  6. study identifies dystonin, a cytoskeleton cross-linker involved in microtubule-based transport, as a binding partner of the HSV-1 protein pUL37, implicated in capsid transport; study provides insight into cellular requirements for HSV-1 capsid transport and identifies dystonin as a nonmotor protein part of transport machinery

  7. There is a significantly enhanced ratio between the dynorphin A (show PDYN Proteins) immunoreactive area and the whole area of the entopeduncular nucleus in genetically dystonic hamsters compared to controls.

  8. This is the first report of a defect in the neuronal isoform of dystonin in humans.

  9. in motile cells Col (show HDAC1 Proteins) XVII recruits BPAG1e to alpha6beta4 integrin and is necessary for activation of signaling pathways, motile behavior, and lamellipodial stability.

  10. Bullous pemphigoid antigen 1 (BPAG1) was identified as a melanoma antigen recognized by its auto-antibody.

Mouse (Murine) Dystonin (DST) interaction partners

  1. oligodendrocytes do not have an intrinsic requirement for neuronal dystonin for differentiation and myelination.

  2. Novel Dst(Gt) mice showed that a loss-of-function mutation in the actin-binding domain-containing Dystonin isoforms led to typical dystonia musculorum phenotypes

  3. Restoration of dystonin-a2 expression in the nervous system prevented the disorganization of organelle membranes and microtubule networks in a mouse model of hereditary sensory and autonomic neuropathy.

  4. This study provides insight into the mechanism of dt neuropathology and proposes a role for dystonin-a2 as a mediator of normal ER structure and function.

  5. novel functions of the dystonin-a2 isoform in mediating microtubule stability, Golgi organization, and flux through the secretory pathway.

  6. Microtubule associated protein 1B, a microtubule stabilizing protein, and clathrin heavy chain, the major component of the clathrin triskelion, were identified as interaction partners for dystonin-a

  7. dystonin does not significantly influence the structural organization of cardiac muscle fibers during early postnatal development

  8. BPAG1-b was detectable in vitro and in vivo as a high molecular mass protein in striated (show NSDHL Proteins) and heart muscle cells, co-localizing with alpha-actinin-2 (show ACTN2 Proteins) and partially with the cytolinker plectin as well as with the intermediate filament protein desmin (show DES Proteins).

  9. BPAG1 has three kinds of cytoskeletal binding domains and seems to play an important role in linking the different types of cytoskeletons.

  10. Transcripts for both neural isoforms of Bpag1 (a1 and a2) were detected in optic nerves and spinal cords of wild-type mice.

Dystonin (DST) Protein Profile

Protein Summary

This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.

Gene names and symbols associated with Dystonin Proteins (DST)

  • dystonin (DST)
  • dystonin (dst)
  • dystonin (Smp_159110)
  • dystonin (Dst)
  • 2310001O04Rik protein
  • A830042E19Rik protein
  • ah protein
  • athetoid protein
  • AW554249 protein
  • BP230 protein
  • BP240 protein
  • BPA protein
  • Bpag protein
  • Bpag1 protein
  • BPAG1-n protein
  • CATX-15 protein
  • CATX15 protein
  • D6S1101 protein
  • DKFZp469H1318 protein
  • DMH protein
  • dst protein
  • dt protein
  • fc38a05 protein
  • HSAN6 protein
  • Macf2 protein
  • mKIAA0728 protein
  • nmf203 protein
  • nmf339 protein
  • wu:fc38a05 protein

Protein level used designations for Dystonin Proteins (DST)

dystonin , bullous pemphigoid antigen 1 , bullous pemphigoid antigen 1, isoforms 1/2/3/4/5/8-like , bullous pemphigoid antigen 1, 230/240kDa , dystonia musculorum protein , hemidesmosomal plaque protein , trabeculin-beta , BPA , bullous pemphigoid antigen 1, isoforms 1/2/3/4 , bullous pemphigoid antigen 1, isoforms 6/7 , microtubule actin cross-linking factor 2

100056885 Equus caballus
474948 Canis lupus familiaris
535297 Bos taurus
693241 Macaca mulatta
100174353 Pongo abelii
324678 Danio rerio
421884 Gallus gallus
100302708 Saccoglossus kowalevskii
733202 Xenopus laevis
8354651 Schistosoma mansoni
100092576 Ornithorhynchus anatinus
100152205 Sus scrofa
100409107 Callithrix jacchus
100430705 Macaca mulatta
100542468 Meleagris gallopavo
100600859 Nomascus leucogenys
667 Homo sapiens
13518 Mus musculus
316313 Rattus norvegicus
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