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Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. Additionally we are shipping and many more products for this protein.
Showing 10 out of 23 products:
Human Polyclonal DRP2 Primary Antibody for IF, IHC - ABIN1531738
Goshima, Nakamura, Strittmatter, Strittmatter: Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33. in Nature 1995
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Human Polyclonal DRP2 Primary Antibody for IF, IHC - ABIN1532768
Hamajima, Matsuda, Sakata, Tamaki, Sasaki, Nonaka: A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution. in Gene 1997
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study implies that dysregulation of CRMP2 (show DPYSL2 Antibodies) may be involved in pathophysiology of neuropsychiatric disorders
we demonstrate that Cdk5 (show CDK5 Antibodies) phosphorylates collapsin response mediator protein 2 (CRMP2 (show DPYSL2 Antibodies)) in the dendritic spines of cultured hippocampal neurons and in vivo in the mouse brain. When we eliminated CRMP2 (show DPYSL2 Antibodies) phosphorylation in CRMP2 (show DPYSL2 Antibodies)(KI/KI (show AXIN1 Antibodies)) mice, the densities of dendritic spines significantly decreased in hippocampal CA1 (show CA1 Antibodies) pyramidal neurons in the mouse brain.
We propose that CRMP2 (show DPYSL2 Antibodies) could contribute to long-lasting synaptic plasticity.
This study shows that in young adult mice, motor and sensory functions lost by SCI can be recovered with a single genetic mutation to inhibit CRMP2 (show DPYSL2 Antibodies) phosphorylation
Study showed that axon degeneration is an early and dominant feature in dopaminergic neurons treated with 1-methyl-4-phenylpyridiniumion (MPP+), and that the Akt/GSK-3beta/CRMP-2 pathway is involved in axon degeneration induced by MPP+
Clear differences in CRMP2 (show DPYSL2 Antibodies) protein abundance and degradation product/short isoform were observed between ischemic core and penumbra (show TSPAN33 Antibodies) and also compared to the contralateral healthy tissues after PACAP38 (show ADCYAP1 Antibodies) or saline treatment.
Glycogen synthase kinase 3beta has a role in microtubule remodeling in compensatory glomerular adaptation to podocyte depletion through Tau and CRMP2 (show DPYSL2 Antibodies)
Levels of total GSK3 (show GSK3b Antibodies) were decreased in the Huntington disease (show HTT Antibodies)-affected frontal cortex and this correlated with decreased phosphorylated CRMP2 (show DPYSL2 Antibodies).
Long-term vitamin E-deficiency led to significantly increased expression of the phosphorylated form of collapsin (show SEMA3A Antibodies) response mediator protein (CRMP)-2 (show DPYSL2 Antibodies) compared to short-term deficiency.
Noncanonical kainate receptor signaling influences neuronal development by modulating CRMP2 (show DPYSL2 Antibodies) activity.
Among the genes found disrupted in this study, there is evidence suggesting that YWHAZ (show YWHAZ Antibodies) and also the X-linked DRP2 (show DPYSL2 Antibodies) may be considered as novel autism candidate genes.
Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord. Two transcript variants encoding different isoforms have been found for this gene.
dystrophin related protein 2
, dystrophin-related protein 2-like
, dystrophin-related protein 2
, collapsin response mediator protein 2
, dihydropyrimidinase-related protein 2
, unc-33-like phosphoprotein 2
, dystrophin-related protein 2 A-form