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anti-E4F Transcription Factor 1 (E4F1) Antibodies

The zinc finger protein encoded by E4F1 is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. Additionally we are shipping E4F1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
E4F1 1877 Q66K89
E4F1 13560 Q8CCE9
E4F1 681359  
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Top anti-E4F1 Antibodies at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated WB Western Blot analysis of E4F1 expression in transfected 293T cell line by E4F1 monoclonal antibody (M03), clone 4B10. Lane 1: E4F1 transfected lysate(83.5 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, ELISA, WB Western Blot analysis of E4F1 expression in transfected 293T cell line by E4F1 monoclonal antibody (M03), clone 4B10.Lane 1: E4F1 transfected lysate(83.5 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged E4F1 is 0.1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of E4F1 expression in transfected 293T cell line by E4F1 MaxPab polyclonal antibody.Lane 1: E4F1 transfected lysate(86.24 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to E4F1 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB Western Blot analysis of E4F1 expression in transfected 293T cell line by E4F1 MaxPab polyclonal antibody.Lane 1: E4F1 transfected lysate(83.50 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 8 to 10 Days
$595.83
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 11 to 16 Days
$553.14
Details
Human Mouse Un-conjugated IF, ELISA, WB   50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$240.90
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 8 to 10 Days
$815.83
Details

E4F1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
,
,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-E4F1 Antibodies

  1. Human Monoclonal E4F1 Primary Antibody for WB - ABIN393753 : Cvetanovic, Rooney, Garcia, Toporovskaya, Zoghbi, Opal: The role of LANP and ataxin 1 in E4F-mediated transcriptional repression. in EMBO reports 2007 (PubMed)
    Show all 5 references for ABIN393753

More Antibodies against E4F1 Interaction Partners

Human E4F Transcription Factor 1 (E4F1) interaction partners

  1. Whole exome sequencing has unraveled the presence of pathogenic mutations in genes encoding non-mitochondrial proteins, such as in the transcription factor E4F1.

  2. results suggest that E4F1 may neutralize the capacity of HBx to activate a p53 (show TP53 Antibodies)-dependent, metabolic and growth arrest phenotype in liver cells, thus possibly contributing to the viability and proliferation of HBV-infected cells

  3. Short hairpin RNA-mediated depletion of E4F1 induced mitochondrial defects and ROS-mediated death in several myeloid leukemia cell lines.

  4. association of p120E4F with p14ARF (show CDKN2A Antibodies) enhances cell cycle inhibition

  5. Specific inactivation of RASSF1A (show RASSF1 Antibodies) by short interfering RNA disrupts binding of RASSF1A (show RASSF1 Antibodies) to p120 (show HNRNPU Antibodies)(E4F) in tumor cells.

  6. E4F1 function involves ER alpha (show ESR1 Antibodies)-mediated inhibition of VSMC proliferation and estrogen-related atheroprotection of human

  7. findings show that full-length E4F1 protein but not its E1A (show BCKDHA Antibodies)-activated & truncated form interacts in vitro & in vivo with FHL2 (show FHL2 Antibodies); this E4F1-FHL2 (show FHL2 Antibodies) association occurs in the nuclear compartment & inhibits the capacity of E4F1 to block cell proliferation

  8. E4F1 is a key posttranslational regulator of p53 (show TP53 Antibodies), which modulates its effector functions involved in alternative cell fates: growth arrest or apoptosis.

  9. LANP (show ANP32A Antibodies) and ATAXN1 interact in E4F-mediated transcriptional repression.

Mouse (Murine) E4F Transcription Factor 1 (E4F1) interaction partners

  1. Acute inactivation of E4F1 in these cells results in CHK1 (show CHEK1 Antibodies)-dependent checkpoint deficiency and multiple mitochondrial dysfunctions that lead to increased ROS (show ROS1 Antibodies) production, energy stress, and inhibition of de novo pyrimidine synthesis

  2. Altogether, our results classify E4F1 as a master regulator of CHK1 (show CHEK1 Antibodies) activity that ensures high fidelity of DNA replication, thus safeguarding genome stability.

  3. deletion of E4F1 resulted in the death of histiocytic sarcoma cells and tumor regression in vivo and extended the lifespan

  4. identify a regulatory axis essential for epidermal stem cell-dependent skin homeostasis implicating E4F1 and the Bmi1 (show BMI1 Antibodies)-Arf (show CDKN2A Antibodies)-p53 (show TP53 Antibodies) pathway.

  5. Results establish a crucial role for E4F during early embryonic cell cycles and reveal an unexpected function for E4F in mitosis.

E4F1 Antigen Profile

Protein Summary

The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence.

Gene names and symbols associated with E4F1

  • E4F transcription factor 1 (E4F1) antibody
  • E4F transcription factor 1 (e4f1) antibody
  • E4F transcription factor 1 (LOC100224725) antibody
  • E4F transcription factor 1 (E4f1) antibody
  • Dnase1l2 antibody
  • E4F antibody
  • MGC147041 antibody
  • zgc:114190 antibody

Protein level used designations for E4F1

transcription factor E4F1 , E4F transcription factor 1 , p120E4F , transcription factor E4F1-like , p50E4F , putative E3 ubiquitin-protein ligase E4F1 , transcription factor E4F , transcription factor phi AP3 , deoxyribonuclease 1-like 2

GENE ID SPECIES
515997 Bos taurus
100517704 Sus scrofa
100683433 Canis lupus familiaris
416560 Gallus gallus
454356 Pan troglodytes
548399 Xenopus (Silurana) tropicalis
695882 Macaca mulatta
100190769 Xenopus laevis
100224725 Taeniopygia guttata
100404813 Callithrix jacchus
100552753 Anolis carolinensis
100580177 Nomascus leucogenys
1877 Homo sapiens
13560 Mus musculus
681359 Rattus norvegicus
561158 Danio rerio
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