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E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) Proteins (ELF3)

Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Additionally we are shipping ELF3 Antibodies (118) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ELF3 13710 Q3UPW2
ELF3 304815 Q4V7E1
ELF3 1999 P78545
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Top ELF3 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,091.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ELF3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

More Proteins for E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) Interaction Partners

Mouse (Murine) E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) interaction partners

  1. a novel role for ELF3 (show EFNB3 Proteins) as a procatabolic factor that may contribute to cartilage remodeling and degradation by regulating MMP13 (show MMP13 Proteins) gene transcription.

  2. A novel function of Elf3 (show EFNB3 Proteins) is identified that defines allergic airway inflammation caused by the regulation of dendritic cell-driven T helper (Th)1 (show TH1L Proteins) cell, Th2 cell, and Th17 cell differentiation.

  3. Elf3 (show EFNB3 Proteins) plays an important role in the regulation of lung cell proliferation and differentiation during repair of the injured bronchiolar airway epithelium.

  4. ESE-1 is an Ang II (show AGT Proteins)-inducible transcription factor that plays an important counter-regulatory role in the setting of vascular inflammation and remodeling.

  5. Elf3 (show EFNB3 Proteins) amino acid residues within the flanking region, including Trp361, are important for the structural integrity of the protein as well as for the Efl3 (show EFNB1 Proteins) DNA binding and transactivation activity.

  6. Like other Ets (show ETS1 Proteins)-family members, Elf3 (show EFNB3 Proteins) functions as a sequence-specific DNA-binding transcriptional factor

  7. Results reveal that Crif1 (show GADD45GIP1 Proteins) is a novel and essential transcriptional coactivator of Elf3 (show EFNB3 Proteins) for the terminal differentiation of absorptive enterocytes.

  8. Evidence that mElf (show EPM2A Proteins)-3, a member of the Ets (show ETS1 Proteins) family, plays a key role in the activation of the mTbetaR-II promoter.

  9. ErbB2 (show ERBB2 Proteins) activation of ESX gene expression

  10. Both proximal and distal regions that regulate Elf3 (show EFNB3 Proteins) promoter activity were identified.

Human E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3) interaction partners

  1. ELF3 is a frequently mutated tumor suppressor gene of periampullary tumors.

  2. ELF3 is a novel transcriptional repressor of estrogen receptor alpha (show ESR1 Proteins) in breast cancer cells.

  3. suggest that ESE-1 may play a role in regulating airway inflammation by regulating ICAM-1 (show ICAM1 Proteins) expression

  4. our data suggested that ESE1/ELF3 may promote the UC progression via accelerating NF-kappaB (show NFKB1 Proteins) activation and thus facilitating IEC apoptosis.

  5. data suggest that polyomavirus enhancer activator 3 and epithelium-specific transcription factor-1 may play important roles in pluri potent and tumorigenic embryonic carcinoma cells.

  6. data identify Elf3 as a pivotal driver for beta-catenin (show CTNNB1 Proteins) signaling in CRC (show CALR Proteins), and highlight potential prognostic and therapeutic significance of Elf3 in CRC (show CALR Proteins).

  7. ESE-1 actS as an upstream effector to regulate OCT4 (show POU5F1 Proteins) transcription in NCCIT pluripotent embryonic carcinoma cells.

  8. The physical interaction between ELF3 and androgen receptor (AR (show AR Proteins)) inhibits the recruitment of AR to specific androgen response elements within target gene promoters.

  9. ELF3 is a candidate transcriptional regulator involved in human urothelial cytodifferentiation.

  10. The concordant upregulation of ESE1/ELF3 and NF-kappaB (show NFKB1 Proteins) in human prostate tumors.

ELF3 Protein Profile

Protein Summary

Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).

Gene names and symbols associated with ELF3

  • E74-like factor 3 (ets domain transcription factor, epithelial-specific) (elf3)
  • E74-like factor 3 (Elf3)
  • E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ELF3)
  • EPR-1 protein
  • ERT protein
  • ESE-1 protein
  • ESX protein
  • jen protein

Protein level used designations for ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific) , ETS-related transcription factor Elf-3 , epithelial-restricted with serine box , epithelium-restricted Ets protein ESX , epithelium-specific Ets transcription factor 1 , E74-like factor 3 (ETS domain transcription factor, serine box, epithelial-specific) , E74-like factor 3 (ets domain transcription factor) , ets domain transcription factor, serine box (epithelial-specific)

GENE ID SPECIES
100144720 Xenopus (Silurana) tropicalis
13710 Mus musculus
304815 Rattus norvegicus
1999 Homo sapiens
508503 Bos taurus
490235 Canis lupus familiaris
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