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ELF1 encodes an E26 transformation-specific related transcription factor. Additionally we are shipping ELF1 Antibodies (90) and ELF1 Kits (2) and many more products for this protein.
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Human ELF1 Protein expressed in Escherichia coli (E. coli) - ABIN2720126
Makowski, Willems, Fang, Choi, Zhang, Jansen, Brown, Vermeulen: An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations. in Proteomics 2016
Green Tea Polyphenol EGCG Upregulates Tollip (show TOLLIP Proteins) Expression by Suppressing Elf-1 (show EFNA2 Proteins) Expression
Herein, the authors demonstrate that mice lacking Sts (show STS Proteins) expression are significantly resistant to infection by the live vaccine strain of Francisella tularensis.
Whereas the proportion of NK cells in Elf-1 (show EFNA2 Proteins)(-/-) mice was normal, the proportion of NKT (show CTSL1 Proteins) cells was significantly reduced in the thymus and periphery of Elf-1 (show EFNA2 Proteins)(-/-) mice compared with wild-type mice.
crystal structure of the phosphatase domain of Sts-1 (show STS1 Proteins), Sts-1 (show STS1 Proteins)(PGM (show Vcan Proteins)), was determined at pH 4.6.The asymmetric unit contains two independent molecules and each active site is occupied by a sulfate ion.
Results suggest that GATA-2 (show GATA2 Proteins), Fli-1 (show FLI1 Proteins) and Elf-1 (show EFNA2 Proteins) are key components of an enhanceosome responsible for activating SCL (show TAL1 Proteins) transcription and establishing the transcriptional programme required for HSC (show FUT1 Proteins) formation.
These results suggest that several Ets (show ETS1 Proteins) factors, including Fli1 (show FLI1 Proteins) itself, are involved in the transcriptional regulation of Fli1 (show FLI1 Proteins) in lymphocytes.
The Sts-1,2 proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathways.
ELF1 (show EFNA2 Proteins) binding occurs at both TERT (show TERT Proteins) promoter mutations in melanoma in vitro such that increased recruitment of GABP is enabled by the spatial architecture of native and novel ETS (show ETS1 Proteins) motifs in the TERT (show TERT Proteins) promoter region.
ELF-1 (show EFNA2 Proteins) binds an important duplicated GGAA cis (show CISH Proteins)-acting element at the OAS1 (show OAS1 Proteins) promoter and in cooperation with RB1 (show RB1 Proteins) and SP1 (show PSG1 Proteins) recruitment contributes to regulation in response to IFN stimulation.
Data suggest that Elf-1 (show EFNA2 Proteins) may modulate breast cancer progression to some extent without having an impact on survival of breast cancer patients.
Expression of FLI-1 (show FLI1 Proteins), ELF-1 (show EFNA2 Proteins), and GABP activated the PF4 (show PF4 Proteins) promoter in HepG2 cells.
The expression of Elf-1 (show EFNA2 Proteins) and survivin (show BIRC5 Proteins) in non-small cell lung cancer is related to differentiation, lymphatic metastasis, clinical stage, and prognosis, and both are positively correlated with microvessel density.
the results indicate that insufficient O-GlcNAc (show OGT Proteins) modification prevents Elf-1 (show EFNA2 Proteins)-mediated transcriptional repression and thereby upregulates Tollip (show TOLLIP Proteins) gene expression in intestinal epithelial cells.
through a genome-wide association in a Hong Kong Chinese cohort and replication in 2 other Asian populations, identified association of ELF1 (show EFNA2 Proteins) with systemic lupus erythematosus
The expression levels of both Elf-1 and VEGF were significantly related with tumor differentiation, lymphatic metastasis, clinical stage, and postoperative survival time in non-small cell lung cancer.
ETS transcription factor (show FEV Proteins) ELF1 (show EFNA2 Proteins) is an important positive regulator of MEIS1 (show MEIS1 Proteins) expression
Data show that VEGFR1 (show FLT1 Proteins) promoter binding sites for ELF-1 (show EFNA2 Proteins), CREB (show CREB1 Proteins) and EGR-1 (show EGR1 Proteins)/3 play a positive role in gene transcription in endothelial cells.
This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants.
ETS-related transcription factor Elf-1
, E74-like factor 1 (ets domain transcription factor)