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anti-EDAR-Associated Death Domain (EDARADD) Antibodies

EDARADD was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. Additionally we are shipping EDARADD Proteins (4) and EDARADD Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EDARADD 171211  
EDARADD 128178 Q8WWZ3
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Top anti-EDARADD Antibodies at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μL Log in to see 3 to 4 Days
$157.06
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$273.90
Details

EDARADD Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human


More Antibodies against EDARADD Interaction Partners

Mouse (Murine) EDAR-Associated Death Domain (EDARADD) interaction partners

  1. crinkled binds EDAR (show EDAR Antibodies) through a homotypic death domain interaction and mediates engagement of the NF-kappaB (show NFKB1 Antibodies) pathway, possibly by recruiting TRAF2 (show TRAF2 Antibodies) to the receptor-signaling complex.

  2. level of activation of Edar (show EDAR Antibodies) thus determines cusp number and tooth number during tooth development

Human EDAR-Associated Death Domain (EDARADD) interaction partners

  1. The study data demonstrate an association between SNP rs3916983 of the EDARADD gene and non-syndromic hypodontia in Chinese Han individuals.

  2. The phenotypes associated with EDA1 (show EDA Antibodies), EDAR (show EDAR Antibodies), and EDARADD mutations were indistinguishable

  3. a cohort of 93 Swedish probands with non-syndromic, isolated oligodontia, mutations were identified in the EDARADD), AXIN2 (show AXIN2 Antibodies), MSX1 (show MSX1 Antibodies), and PAX9 (show PAX9 Antibodies) genes

  4. Results demonstrate that EDARADD mutations are not a frequent cause of hypohidrotic ectodermal dysplasia, while mutations in TRAF6 (show TRAF6 Antibodies), TAB2 (show TAB2 Antibodies) and TAK1 (show MAP3K7 Antibodies) may not be implicated in this disease.

  5. interacts with the death domain of Edar (show EDAR Antibodies) and links the receptor to downstream signalling pathways

  6. crinkled binds EDAR (show EDAR Antibodies) through a homotypic death domain interaction and mediates engagement of the NF-kappaB (show NFKB1 Antibodies) pathway, possibly by recruiting TRAF2 (show TRAF2 Antibodies) to the receptor-signaling complex

EDARADD Antigen Profile

Protein Summary

This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene names and symbols associated with EDARADD

  • EDAR (ectodysplasin-A receptor)-associated death domain (Edaradd) antibody
  • EDAR-associated death domain (EDARADD) antibody
  • 1810032E07Rik antibody
  • 5830469M23Rik antibody
  • A630043P06 antibody
  • cr antibody
  • ECTD11A antibody
  • ECTD11B antibody
  • ED3 antibody
  • EDA3 antibody

Protein level used designations for EDARADD

EDAR-associated death domain protein , crinkled , ectodysplasin-A receptor-associated adapter protein , crinkled homolog , ectodysplasia A receptor associated death domain , ectodysplasin A receptor associated adapter protein

GENE ID SPECIES
171211 Mus musculus
128178 Homo sapiens
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