You are viewing an incomplete version of our website. Please click to reload the website as full version.

EDAR-Associated Death Domain Proteins (EDARADD)

EDARADD was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. Additionally we are shipping EDARADD Antibodies (4) and EDARADD Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EDARADD 171211  
EDARADD 128178 Q8WWZ3
EDARADD    
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top EDARADD Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,504.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

EDARADD Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

Macaca fascicularis

More Proteins for EDAR-Associated Death Domain (EDARADD) Interaction Partners

Mouse (Murine) EDAR-Associated Death Domain (EDARADD) interaction partners

  1. crinkled binds EDAR (show EDAR Proteins) through a homotypic death domain interaction and mediates engagement of the NF-kappaB (show NFKB1 Proteins) pathway, possibly by recruiting TRAF2 (show TRAF2 Proteins) to the receptor-signaling complex.

  2. level of activation of Edar (show EDAR Proteins) thus determines cusp number and tooth number during tooth development

Human EDAR-Associated Death Domain (EDARADD) interaction partners

  1. The study data demonstrate an association between SNP rs3916983 of the EDARADD gene and non-syndromic hypodontia in Chinese Han individuals.

  2. The phenotypes associated with EDA1 (show EDA Proteins), EDAR (show EDAR Proteins), and EDARADD mutations were indistinguishable

  3. a cohort of 93 Swedish probands with non-syndromic, isolated oligodontia, mutations were identified in the EDARADD), AXIN2 (show AXIN2 Proteins), MSX1 (show MSX1 Proteins), and PAX9 (show PAX9 Proteins) genes

  4. Results demonstrate that EDARADD mutations are not a frequent cause of hypohidrotic ectodermal dysplasia, while mutations in TRAF6 (show TRAF6 Proteins), TAB2 (show TAB2 Proteins) and TAK1 (show MAP3K7 Proteins) may not be implicated in this disease.

  5. interacts with the death domain of Edar (show EDAR Proteins) and links the receptor to downstream signalling pathways

  6. crinkled binds EDAR (show EDAR Proteins) through a homotypic death domain interaction and mediates engagement of the NF-kappaB (show NFKB1 Proteins) pathway, possibly by recruiting TRAF2 (show TRAF2 Proteins) to the receptor-signaling complex

EDARADD Protein Profile

Protein Summary

This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene names and symbols associated with EDARADD

  • EDAR (ectodysplasin-A receptor)-associated death domain (Edaradd)
  • EDAR-associated death domain (EDARADD)
  • 1810032E07Rik protein
  • 5830469M23Rik protein
  • A630043P06 protein
  • cr protein
  • ECTD11A protein
  • ECTD11B protein
  • ED3 protein
  • EDA3 protein

Protein level used designations for EDARADD

EDAR-associated death domain protein , crinkled , ectodysplasin-A receptor-associated adapter protein , crinkled homolog , ectodysplasia A receptor associated death domain , ectodysplasin A receptor associated adapter protein

GENE ID SPECIES
171211 Mus musculus
128178 Homo sapiens
Selected quality suppliers for EDARADD Proteins (EDARADD)
Did you look for something else?