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anti-EF-Hand Domain Family, Member D2 (EFHD2) Antibodies

May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Additionally we are shipping EF-Hand Domain Family, Member D2 Kits (6) and EF-Hand Domain Family, Member D2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EFHD2 27984  
EFHD2 79180 Q96C19
EFHD2 298609 Q4FZY0
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Top anti-EF-Hand Domain Family, Member D2 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-EFHD2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185311 (0.1µg/ml) staining of human lymph node lysate. Primary inc... ABIN185311 (0.3µg/ml) staining of paraffin embedded human tonsil. Micr... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Western blot analysis of EFHD2 in mouse brain tissue lysate with AP303... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated ELISA, IHC (p), WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$330.00
Details

EFHD2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , ,
,
Human , , , ,
,
Rat (Rattus) , , ,
,

Top referenced anti-EF-Hand Domain Family, Member D2 Antibodies

  1. Human Polyclonal EFHD2 Primary Antibody for IHC, ELISA - ABIN185311 : Vuadens, Rufer, Kress, Corthésy, Schneider, Tissot: Identification of swiprosin 1 in human lymphocytes. in Proteomics 2004 (PubMed)
    Show all 3 references for ABIN185311

  2. Cow (Bovine) Polyclonal EFHD2 Primary Antibody for WB - ABIN2787767 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against EF-Hand Domain Family, Member D2 Interaction Partners

Mouse (Murine) EF-Hand Domain Family, Member D2 (EFHD2) interaction partners

  1. These results show that EFhd2 is not essential for platelet function in mice indicating that other cytoskeletal adaptors may functionally compensate its loss.

  2. EFhd2 is a neuronal protein that interferes with kinesin-mediated transport.

  3. a role is found for EFhd2 as a negative regulator of germinal center-dependent humoral type 2 immunity, with implications for the generation of IgE.

  4. Swiprosin-1 is involved in regulating the accessibility of F-actin to cofilin (show CFL1 Antibodies) through the clustering of F-actin and the activity of Swiprosin-1 is highly dependent on its phosphorylation status at Ser183

  5. Characterized EFhd2's calcium binding activity. Results showed mutations of a conserved aspartate on either EF-hand motif disrupted calcium binding activity, indicating that these motifs work in pair as a functional calcium binding domain.

  6. EFhd2 may play an important role in the pathobiology of tau-mediated neurodegeneration.

  7. Swip-1 (show WSB1 Antibodies) provides a membrane scaffold that is required for the Syk (show SYK Antibodies)-, SLP-65 (show BLNK Antibodies)-, and PLCgamma2 (show PLCG2 Antibodies)-dependent BCR (show BCR Antibodies)-induced calcium flux.

  8. study shows that swiprosin-1 may regulate lifespan and BCR (show BCR Antibodies) signaling thresholds in immature B cells

  9. The identification of a novel calcium-binding protein (show GUCA1B Antibodies) associated with tau protein in terminally ill tauopathy mouse model suggests that this association may play an important physiological and/or pathological role.

  10. These results suggest that swiprosin-1 is a PKC-beta (show PRKCB Antibodies) I/eta-inducible gene and it modulates mast cell activation through NF-kappaB (show NFKB1 Antibodies)-dependent pathway.

Human EF-Hand Domain Family, Member D2 (EFHD2) interaction partners

  1. The results imply that EFhd2's physiological and/or pathological function could be regulated by its phosphorylation state.

  2. EFhd2 is involved in the control of synapse development and maintenance and is linked to dementia.

  3. Swiprosin-1 localizes to microvilli-like membrane protrusions and lamellipodia and exhibits actin-binding activity.

  4. Swiprosin-1 is involved in regulating the accessibility of F-actin to cofilin (show CFL1 Antibodies) through the clustering of F-actin and the activity of Swiprosin-1 is highly dependent on its phosphorylation status at Ser183

  5. EFhd2 may play an important role in the pathobiology of tau-mediated neurodegeneration.

  6. the human Shu complex (hSWS1.SWSAP1 (show SWSAP1 Antibodies)) has an evolutionarily conserved function in homologous recombination

  7. Its predominant presence in CD8 (show CD8A Antibodies) lymphocytes suggests that swiprosin-1 may be involved in functions that are important for cytotoxic lymphocytes.

  8. These results suggest that swiprosin-1 is a PKC-beta (show PRKCB Antibodies) I/eta-inducible gene and it modulates mast cell activation through NF-kappaB (show NFKB1 Antibodies)-dependent pathway.

EF-Hand Domain Family, Member D2 (EFHD2) Antigen Profile

Protein Summary

May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance (By similarity).

Gene names and symbols associated with EFHD2

  • EF-hand domain family, member D2 (EFHD2) antibody
  • EF-hand domain family, member D2 (efhd2) antibody
  • EF-hand domain family, member D2 (LOC100345208) antibody
  • EF-hand domain-containing protein D2 (efhd2) antibody
  • EF hand domain containing 2 (Efhd2) antibody
  • EF-hand domain family, member D1 (efhd1) antibody
  • EF-hand domain family, member D2 (Efhd2) antibody
  • 2600015J22Rik antibody
  • AA408606 antibody
  • D4Wsu27e antibody
  • EFHD2 antibody
  • fj19b07 antibody
  • MGC131292 antibody
  • si:ch211-281l24.1 antibody
  • si:dkey-72l14.9 antibody
  • SWS1 antibody
  • wu:fb80e07 antibody
  • wu:fj19b07 antibody

Protein level used designations for EFHD2

EF-hand domain family, member D2 , EF hand domain family, member D2 , EF-hand domain-containing protein D2 , swiprosin 1 , swiprosin-1 , EF hand domain containing 2

GENE ID SPECIES
430669 Gallus gallus
496711 Xenopus (Silurana) tropicalis
694155 Macaca mulatta
735013 Xenopus laevis
747200 Pan troglodytes
100345208 Oryctolagus cuniculus
100380618 Salmo salar
571114 Danio rerio
27984 Mus musculus
335521 Danio rerio
79180 Homo sapiens
298609 Rattus norvegicus
514259 Bos taurus
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