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displays differential expression during soleus muscle disuse atrophy. Additionally we are shipping and many more products for this protein.
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This is the first demonstration of MICU2 deficiency in humans, which we suggest causes a distinct neurodevelopmental phenotype secondary to impaired mitochondrial calcium uniporter (show MCU Antibodies)-mediated regulation of intracellular calcium homeostasis.
Expression of MICU2 mutants lacking functional Ca2 (show CA2 Antibodies)+-binding sites leads to a striking loss of Ca2 (show CA2 Antibodies)+ uptake in HEK293 cells.
MICU1 (show MICU1 Antibodies) and MICU2 have roles in tuning the mitochondrial Ca2 (show CA2 Antibodies)+ uniporter by exerting opposite effects on MCU (show MCU Antibodies) activity
regulation of MCU (show MCU Antibodies)-mediated mitochondrial calcium handling
displays differential expression during soleus muscle disuse atrophy
EF-hand domain-containing family member A1
, EF-hand domain family, member A1
, EF hand domain family A1
, EF hand domain family, member A1
, Smhs2 homolog
, calcium uptake protein 2, mitochondrial