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EGF-Like-Domain, Multiple 7 Proteins (EGFL7)

EGFL7 encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. Additionally we are shipping EGFL7 Antibodies (62) and EGFL7 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EGFL7 353156 Q9QXT5
EGFL7 51162 Q9UHF1
Rat EGFL7 EGFL7 245963 Q6AZ60
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Top EGFL7 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag 100 μg Log in to see 16 Days
$492.80
Details
HOST_Baculovirus infected Insect Cells Mouse His tag 100 μg Log in to see 16 Days
$492.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse His tag   20 μg Log in to see 5 Days
$167.48
Details
Insect Cells Human His tag   20 μg Log in to see 5 Days
$167.48
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 15 to 19 Days
$314.16
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

EGFL7 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,

Human , , , ,
,

Top referenced EGFL7 Proteins

  1. Human EGFL7 Protein expressed in Wheat germ - ABIN1352429 : Badiwala, Guha, Tumiati, Joseph, Ghashghai, Ross, Delgado, Rao: Epidermal growth factor-like domain 7 is a novel inhibitor of neutrophil adhesion to coronary artery endothelial cells injured by calcineurin inhibition. in Circulation 2011 (PubMed)
    Show all 2 references for ABIN1352429

  2. Mouse (Murine) EGFL7 Protein expressed in Baculovirus infected Insect Cells - ABIN2007844 : Schmidt, De Mazière, Smyczek, Gray, Parker, Filvaroff, French, van Dijk, Klumperman, Ye: The role of Egfl7 in vascular morphogenesis. in Novartis Foundation symposium 2008 (PubMed)
    Show all 2 references for ABIN2007844

  3. Human EGFL7 Protein expressed in Baculovirus infected Insect Cells - ABIN2004952 : Campagnolo, Moscatelli, Pellegrini, Siracusa, Stuhlmann: Expression of EGFL7 in primordial germ cells and in adult ovaries and testes. in Gene expression patterns : GEP 2008 (PubMed)
    Show all 2 references for ABIN2004952

More Proteins for EGF-Like-Domain, Multiple 7 (EGFL7) Interaction Partners

Xenopus laevis EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. we demonstrate for the first time the mechanisms by which lumens are generated within the major vessels in Xenopus and implicate EGFL7 in modulating cell shape and cell-cell junctions to drive proper lumen morphogenesis.

  2. CASZ1/Egfl7/RhoA (show RHOA Proteins) pathway is necessary for promoting endothelial cell behaviors associated with proper vascular assembly.

Zebrafish EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. These data suggest that Egfl7 provides endothelial cells (EC) with a cue for their extension into the vascular area and in establishing EC cell polarity.

  2. EGFL7 provides a proper microenvironment for endothelial cell migration, thereby enabling accurate patterning.

Mouse (Murine) EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. EGFL7 is required for VEGF (show VEGFA Proteins) upregulation of the Akt (show AKT1 Proteins)/Erk (1 (show MAPK3 Proteins)/2) pathway during angiogenesis.

  2. EGFL7 enhances EGFR (show EGFR Proteins)-AKT (show AKT1 Proteins) signaling, epithelial-mesenchymal transition, and metastasis of gastric cancer cells.

  3. Egfl7 could be a HIF-1alpha (show HIF1A Proteins) responsive gene regulated by oxygen tension.

  4. Using the BPH/5 model of pre-eclampsia (PE), we show that the downregulation of Egfl7 in compromised placentas occurs pr (show NOTCH1 Proteins)ior to the onset of characteristic maternal signs of PE.

  5. egfl7 is initially expressed in all endothelial cells and then is progressively restricted to veins and to their neighbouring capillaries.

  6. EGFL7 is expressed in the bone microenvironment and has a role in promoting endothelial cell migration and tube-like structure formation through integrin-mediated pathways.

  7. Expression of Egfl7 in breast and lung carcinoma cells accelerates tumor growth and metastasis in immunocompetent mice but not in immunodeficient mice.

  8. Overexpression of endothelial Egfl7 is associated with impaired angiogenesis and altered Notch (show NOTCH1 Proteins) signaling

  9. the expression of the VE-statin/egfl7 gene in endothelial cells and the specific importance of ETS (show ETS1 Proteins) and GATA (show QRSL1 Proteins) factors

  10. EGFL7 protein is localized to the endoplasmic reticulum and Golgi apparatus, suggesting that the protein is targeted for secretion

Human EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. The preferential expression of EGFL7 in less differentiated hepatocellular carcinoma compared to VEGF (show VEGFA Proteins), suggests a possible important role of this angiogenic factor (show VEGFA Proteins) in a later oncogenic and infiltrative/metastatic phase.

  2. EGFR (show EGFR Proteins) mutational analysis is useful in the diagnosis of non-small-cell-lung cancer.

  3. The aim of the present descriptive study was to analyse the intra-tumoural expressions of epidermal growth factor (show EGF Proteins)-like domain 7 (EGFL7) and microRNA-126 (miRNA-126) in primary tumours from patients with stage II-IV colorectal cancer.

  4. EGFL7, OPN (show SPP1 Proteins), and PGE2 may have a role in recurrence and metastasis of hepatocellular carcinoma

  5. High EGFL7 expression promotes migration and Epithelial-Mesenchymal Transition in pancreatic Cancer.

  6. Loss of EGFL7 expression is associated with Malignant Pleural Mesothelioma.

  7. Data suggest that, in trophoblast cells, EGFL7 regulates cell migration and invasion/placentation by activating multiple signaling pathways via MAPK (show MAPK1 Proteins), PI3K (show PIK3CA Proteins) (phosphatidylinositol 3-kinase), and NOTCH1 (show NOTCH1 Proteins) (translocation-associated notch (show NOTCH1 Proteins) protein 1).

  8. EGFL7 may predict response to first-line chemotherapy and bevacizumab in patients with metastatic colorectal cancer

  9. Endothelial cells control pancreatic cell fate at defined stages through EGFL7 signaling.

  10. EGFL7 enhances EGFR (show EGFR Proteins)-AKT (show AKT1 Proteins) signaling, epithelial-mesenchymal transition, and metastasis of gastric cancer cells.

EGFL7 Protein Profile

Protein Summary

This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with EGFL7

  • EGF-like-domain, multiple 7 (egfl7)
  • EGF-like-domain, multiple 7 (EGFL7)
  • EGF-like-domain, multiple 7 (LOC100226311)
  • EGF-like domain 7 (Egfl7)
  • EGF-like-domain, multiple 7 (Egfl7)
  • EGFL7 protein
  • MGC53105 protein
  • MGC147423 protein
  • NEU1 protein
  • RP11-251M1.2 protein
  • VE-STATIN protein
  • xegfl7 protein
  • zgc:136669 protein
  • zgc:152804 protein
  • ZNEU1 protein

Protein level used designations for EGFL7

EGF-like-domain, multiple 7 , epidermal growth factor-like protein 7 , rp11-251m1.2 , EGF-like protein 7 , NEU1 protein , NOTCH4-like protein , multiple EGF-like domains protein 7 , multiple epidermal growth factor-like domains protein 7 , vascular endothelial statin , vascular endothelial-statin , EGF-like domain 7 , EGF-like domain-containing protein 7 , Estrogen-regulated protein CBL20 20.4kD , Estrogen-regulated protein CBL20, 20.4kD , multiple EGF-like domain protein 7 , multiple epidermal growth factor-like domain protein 7

GENE ID SPECIES
379835 Xenopus laevis
417137 Gallus gallus
464868 Pan troglodytes
491250 Canis lupus familiaris
613671 Bos taurus
678640 Danio rerio
780371 Xenopus (Silurana) tropicalis
100226311 Taeniopygia guttata
353156 Mus musculus
51162 Homo sapiens
245963 Rattus norvegicus
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