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EH-Domain Containing 2 Proteins (EHD2)

EHD2 encodes a member of the EH domain-containing protein family. Additionally we are shipping EHD2 Antibodies (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EHD2 30846 Q9NZN4
EHD2 259300 Q8BH64
EHD2 361512 Q4V8H8
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Top EHD2 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,551.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

EHD2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus) ,

More Proteins for EH-Domain Containing 2 (EHD2) Interaction Partners

Human EH-Domain Containing 2 (EHD2) interaction partners

  1. Data suggest that the EH-domain containing 2 protein (EHD2) NPF phenylalanine residue is crucial for EHD2 localization to the plasma membrane, whereas the proline residue is essential for EHD2 dimerization and binding.

  2. EHD2 can inhibit the metastasis of human breast cancer by regulating the epithelial-to-mesenchymal transition markers E-cadherin (show CDH1 Proteins) and N-cadherin (show CDH2 Proteins).

  3. Downregulation of EHD2 was associated with migration and invasion by abrogating the expression of Rac1 in breast cancer patients.

  4. Phosphatidylinositol 4,5-bisphosphate controls EHD2 plasma membrane localization.

  5. Our results suggested that EHD2 low expression is involved in the pathogenesis of human esophageal squamous cell carcinoma

  6. EHD2 participates in the sarcolemma repair.

  7. Assembly of EHD2 stabilized and constrained caveolae to the plasma membrane to control turnover, and depletion of EHD2, resulting in endocytic and more dynamic and short-lived caveolae.

  8. Among three EHD proteins (EHD1-EHD3 (show EHD3 Proteins)) that were tested, only EHD2 accumulates in the nucleus under nuclear export inhibition treatment.

  9. Confining caveolae to the plasma membrane by EHD2 relied on its capacity to link caveolae to actin filaments.

  10. EHD2 regulates trafficking from the plasma membrane by controlling Rac1 activity.

Mouse (Murine) EH-Domain Containing 2 (EHD2) interaction partners

  1. The helical domain of EHD2 (show EHD3 Proteins) is inserted into the membrane.The N terminus domain regulates caveolar targeting of EHD2 (show EHD3 Proteins).

  2. Assembly of EHD2 (show EHD3 Proteins) stabilized and constrained caveolae to the plasma membrane to control turnover, and depletion of EHD2 (show EHD3 Proteins), resulting in endocytic and more dynamic and short-lived caveolae.

  3. The characterization of Fer1L5 and its interaction with EHD1 (show EHD1 Proteins) and EHD2 (show EHD3 Proteins) underscores the complex requirement of ferlin proteins and mediators of endocytic recycling for membrane trafficking events during myotube formation

  4. appears to connect endocytosis to the actin cytoskeleton through interactions of its N-terminal domain with membranes and its C-terminal EH domain with the novel EHBP1 protein

  5. interaction of myoferlin with EHD2 (show EHD3 Proteins) identifies molecular overlap between the endocytic recycling pathway and the machinery that regulates myoblast membrane fusion

EHD2 Protein Profile

Protein Summary

This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.

Gene names and symbols associated with EH-Domain Containing 2 Proteins (EHD2)

  • EH-domain containing 2 (ehd2)
  • EH-domain containing 2 (EHD2)
  • EH-domain containing 2 (Ehd2)
  • BC027084 protein
  • C130052H20Rik protein
  • EHD1 protein
  • fj66d02 protein
  • MGC64266 protein
  • MGC107790 protein
  • MGEPS protein
  • PAST2 protein
  • wu:fj66d02 protein
  • zgc:77671 protein

Protein level used designations for EH-Domain Containing 2 Proteins (EHD2)

EH-domain containing 2 , EH domain-containing protein 2 , EH-domain containing 1 , EH-domain-containing protein 2 , EH domain-containing protein 2-like , EH domain containing 2 , PAST homolog 2 , putative eps protein

GENE ID SPECIES
379503 Xenopus laevis
456170 Pan troglodytes
595056 Xenopus (Silurana) tropicalis
100412235 Callithrix jacchus
100483750 Ailuropoda melanoleuca
30846 Homo sapiens
259300 Mus musculus
484417 Canis lupus familiaris
538348 Bos taurus
361512 Rattus norvegicus
337401 Danio rerio
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