ELK4, ETS-Domain Protein (SRF Accessory Protein 1) Proteins (ELK4)

ELK4 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Additionally we are shipping ELK4, ETS-Domain Protein (SRF Accessory Protein 1) Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ELK4 2005 P28324
Rat ELK4 ELK4 304786  
ELK4 13714 P41158
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Top ELK4, ETS-Domain Protein (SRF Accessory Protein 1) Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 10 to 12 Days
$229.85
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HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
Details

ELK4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

More Proteins for ELK4, ETS-Domain Protein (SRF Accessory Protein 1) (ELK4) Interaction Partners

Human ELK4, ETS-Domain Protein (SRF Accessory Protein 1) (ELK4) interaction partners

  1. Data suggest that SIRT7 (show SIRT7 Proteins) undergoes Lys (show LYZ Proteins)-63 polyubiquitination, later removed by USP7 (show USP7 Proteins) to repress enzymatic activity of SIRT7 (show SIRT7 Proteins); USP7 (show USP7 Proteins) and SIRT7 (show SIRT7 Proteins) regulate gluconeogenesis via expression of glucose-6-phosphatase catalytic subunit (G6PC (show G6PC Proteins)); SIRT7 (show SIRT7 Proteins) targets G6PC (show G6PC Proteins) promoter through ELK4. (SIRT7 (show SIRT7 Proteins) = sirtuin 7 (show SIRT7 Proteins); USP7 (show USP7 Proteins) = ubiquitin specific peptidase 7 (show USP7 Proteins); G6PC (show G6PC Proteins) = glucose-6-phosphatase catalytic subunit (show G6PC Proteins); ELK4 = transcription factor ELK4)

  2. SLC45A3-ELK4 may represent the first description of a recurrent RNA chimaeric transcript specific to prostate cancer that does not have a detectable DNA aberration

  3. ELK4 is overexpressed in melanoma and knocking down the ELK4 or CDK2 (show CDK2 Proteins) expression significantly attenuated the malignant phenotype of melanoma cells

  4. CTCF (show CTCF Proteins) has a role in regulating SLC45A3-ELK4 Chimeric RNA

  5. Data suggest that chimeric SLC45A3-ELK4 controls prostate cancer cell proliferation, and the chimera level correlates with prostate cancer disease progression.

  6. Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex

  7. ELK4 is a direct androgen receptor (show AR Proteins) target in prostate cancer cells. Androgens may thus contribute to the growth of prostate cancer via influencing ELK4 levels

Mouse (Murine) ELK4, ETS-Domain Protein (SRF Accessory Protein 1) (ELK4) interaction partners

  1. Dok-4 (show DOK4 Proteins) can target Elk-4 activity through multiple mechanisms, including binding of the transactivation domain, nuclear exclusion and protein destabilization.

  2. MKL1/2 and ELK4 co-regulate distinct serum response factor (SRF) transcription programs in macrophages.

  3. Data show that Elk-1 and Net do not contribute significantly to thymocyte development in the presence of SAP-1.

  4. SAP-1 is required for Erk (show EPHB2 Proteins)-mediated transcriptional events in thymocyte development.

  5. T cell positive selection, and ERK (show EPHB2 Proteins) signaling to SAP-1 is not required for the suppressive activity of T(reg (show KCNH2 Proteins)) cells.

ELK4, ETS-Domain Protein (SRF Accessory Protein 1) (ELK4) Protein Profile

Protein Summary

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene.

Gene names and symbols associated with ELK4

  • ELK4, ETS-domain protein (SRF accessory protein 1) (elk4-a)
  • ELK4, ETS-domain protein (SRF accessory protein 1) (ELK4)
  • ELK4, ETS-domain protein (SRF accessory protein 1) (Elk4)
  • ELK4, member of ETS oncogene family (Elk4)
  • prosaposin (PSAP)
  • sodium channel and clathrin linker 1 (Sclt1)
  • 2310011G17Rik protein
  • A130026I01Rik protein
  • BB162516 protein
  • CAP-1A protein
  • SAP-1 protein
  • Sap1 protein
  • XSAP1 protein

Protein level used designations for ELK4

ETS domain-containing protein Elk-4 , SAP-1 , serum response factor accessory protein 1 , ELK4, member of ETS oncogene family , SRF accessory protein 1 , proactivator polypeptide , prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) , clathrin-associated protein 1A , sodium channel Nav1.8-binding protein , sodium channel associated protein 1 , sodium channel-associated protein 1

GENE ID SPECIES
378644 Xenopus laevis
2005 Homo sapiens
540309 Bos taurus
304786 Rattus norvegicus
13714 Mus musculus
281433 Bos taurus
266809 Rattus norvegicus
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