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ELKS/RAB6-Interacting/CAST Family Member 1 Proteins (ERC1)

The protein encoded by ERC1 is a member of a family of RIM-binding proteins. Additionally we are shipping ERC1 Antibodies (34) and ERC1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ERC1 23085 Q8IUD2
ERC1 111173 Q99MI1
Rat ERC1 ERC1 266806 Q811U3
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Top ERC1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ERC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1) Interaction Partners

Human ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1) interaction partners

  1. Liprin-alpha1, ERC1a and LL5 also define new highly polarized and dynamic cytoplasmic structures uniquely localized near the protruding cell edge

  2. ATM (show ATM Proteins)- and NEMO (show IKBKG Proteins)-dependent ubiquitination of ELKS leads to the ubiquitin-dependent assembly of TAK1 (show MAP3K7 Proteins)/TAB2 (show TAB2 Proteins)/3 and NEMO (show IKBKG Proteins)/IKK (show CHUK Proteins) complexes, resulting in IKK (show CHUK Proteins) and NF-kappaB (show NFKB1 Proteins) activation following genotoxic stimuli.

  3. Analysis of the gene structure of four isoforms (ELKS beta, ELKS gamma, ELKS delta, and ELKS epsilon) in a case of papillary thyroid carcinoma reveal that the isoforms are produced by alternative splicing.

  4. In vitro results indicate that ERC2/CAST, an active zone-specific isoform, interacts with all of the known isoforms of liprin-alpha and that liprin-alpha1 associates with both ERC2 and ERC1b

  5. ELKS likely functions by recruiting IkappaBalpha (show NFKBIA Proteins) to the IkappaB kinase (show CHUK Proteins) (IKK (show CHUK Proteins)) complex and thus serves a regulatory function for IKK (show CHUK Proteins) activation

  6. ERC1-PDGFRB (show PDGFRB Proteins) fusion is associated with acute myeloid leukemia (show BCL11A Proteins)

Mouse (Murine) ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1) interaction partners

  1. Our results reveal that ELKS is required for normal Ca(2 (show CA2 Proteins)+) influx at nerve terminals of inhibitory hippocampal neurons.

  2. ATM (show ATM Proteins)- and NEMO (show IKBKG Proteins)-dependent ubiquitination of ELKS leads to the ubiquitin-dependent assembly of TAK1 (show NR2C2 Proteins)/TAB2 (show TAB2 Proteins)/3 and NEMO (show IKBKG Proteins)/IKK (show CHUK Proteins) complexes, resulting in IKK (show CHUK Proteins) and NF-kappaB (show NFKB1 Proteins) activation following genotoxic stimuli.

ERC1 Protein Profile

Protein Summary

The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10\;12)(q11\;p13). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ERC1

  • ELKS/RAB6-interacting/CAST family member 1 (ERC1)
  • ELKS/RAB6-interacting/CAST family member 1 (erc1)
  • ELKS/RAB6-interacting/CAST family member 1 (Erc1)
  • 4930404L01Rik protein
  • 5033405M01Rik protein
  • 9630025C19Rik protein
  • B430107L16Rik protein
  • CAST protein
  • Cast2 protein
  • Elks protein
  • ERC protein
  • ERC1b protein
  • mKIAA1081 protein
  • Rab6ip2 protein
  • RAB6IP2A protein
  • RAB6IP2B protein

Protein level used designations for ERC1

ELKS/RAB6-interacting/CAST family member 1 , RAB6-interacting protein 2 , ELKS/RAB6-interacting/CAST family member 1-like , ELKS/Rab6-interacting/CAST family member 1-like , ELKS/Rab6-interacting/CAST family member 1 , RAB6 interacting protein 2 , Rab6-interacting protein 2 , CAST2 , CAZ-associated structural protein 2 , ERC-1 , Rab6 interacting protein 2 , ERC protein 1 , RIM-Binding Protein

GENE ID SPECIES
451740 Pan troglodytes
100050184 Equus caballus
100145199 Xenopus (Silurana) tropicalis
100229781 Taeniopygia guttata
100350081 Oryctolagus cuniculus
100404300 Callithrix jacchus
100474357 Ailuropoda melanoleuca
100540472 Meleagris gallopavo
23085 Homo sapiens
111173 Mus musculus
266806 Rattus norvegicus
418153 Gallus gallus
486753 Canis lupus familiaris
100513988 Sus scrofa
519271 Bos taurus
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