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Interacts with EP300 and acts as a repressor of MYOD- dependent transcription and muscle differentiation. Additionally we are shipping EID2 Proteins (3) and many more products for this protein.
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Human Polyclonal EID2 Primary Antibody for WB - ABIN651820
Lee, Lee, Miyake, Kim: A novel E1A-like inhibitor of differentiation (EID) family member, EID-2, suppresses transforming growth factor (TGF)-beta signaling by blocking TGF-beta-induced formation of Smad3-Smad4 complexes. in The Journal of biological chemistry 2004
Show all 2 references for ABIN651820
EID-2 may function as an endogenous suppressor of TGF-beta (show TGFB1 Antibodies) signaling
Unlike that of EID-2, the C-terminus, but not the N-terminus, of EID-3 (show EID3 Antibodies) was required for nuclear localization. EID-3 (show EID3 Antibodies) formed a homodimer or heterodimer with EID-2
Interacts with EP300 and acts as a repressor of MYOD- dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex (By similarity).
CREBBP/EP300 inhibitor 2
, CREBBP/EP300 inhibitory protein 2
, E1A like inhibitor of differentiation 2
, EID-1-like inhibitor of differentiation 2
, EP300-interacting inhibitor of differentiation 2