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ER Degradation Enhancer, Mannosidase alpha-Like 2 Proteins (EDEM2)

In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). Additionally we are shipping EDEM2 Antibodies (33) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EDEM2 55741 Q9BV94
Mouse EDEM2 EDEM2 108687  
Rat EDEM2 EDEM2 296304  
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Top EDEM2 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

EDEM2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2) Interaction Partners

Human ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2) interaction partners

  1. EDEM2 and OS-9 (show OS9 Proteins) are required for ER-associated degradation of non-glycosylated sonic hedgehog (show SHH Proteins)

  2. Glycoproteins mannose trimming from Man9GlcNAc2 to Man8GlcNAc2 is conducted mainly by EDEM2.

  3. Degrades misfolded alpha1-antitrypsin in the ER.

  4. EDEM2 regulates endoplasmic reticulum-associated glycoprotein degradation

Mouse (Murine) ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2) interaction partners

  1. Data suggest Edem1 (show EDEM1 Proteins)/Edem2 participate in ricin translocation; overexpression of Edem2, in contrast to Edem1 (show EDEM1 Proteins), directly promotes ricin subunit A transport from endoplasmic reticulum (ER) to cytosol; this translocation is not dependent on ER translocon.

EDEM2 Protein Profile

Protein Summary

In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005

Gene names and symbols associated with EDEM2

  • ER degradation enhancer, mannosidase alpha-like 2 (EDEM2)
  • ER degradation enhancer, mannosidase alpha-like 2 (Edem2)
  • ER degradation enhancer, mannosidase alpha-like 2 (edem2)
  • 9530090G24Rik protein
  • AI327354 protein
  • bA4204.1 protein
  • C20orf31 protein
  • C20orf49 protein
  • DKFZp459A0314 protein
  • MGC88910 protein
  • RGD1303074 protein

Protein level used designations for EDEM2

ER degradation-enhancing alpha-mannosidase-like 2 , ER degradation-enhancing alpha-mannosidase-like protein 2 , ER degradation-enhancing-mannosidase-like protein 2 , ER degradation enhancer, mannosidase alpha-like 2 , ER degradation-enhancing alpha-mannosidase-like 2-like

GENE ID SPECIES
55741 Homo sapiens
108687 Mus musculus
296304 Rattus norvegicus
402801 Danio rerio
448548 Xenopus (Silurana) tropicalis
458197 Pan troglodytes
477209 Canis lupus familiaris
513253 Bos taurus
706150 Macaca mulatta
770034 Gallus gallus
100032432 Monodelphis domestica
100174723 Pongo abelii
100344900 Oryctolagus cuniculus
100395668 Callithrix jacchus
100482741 Ailuropoda melanoleuca
100543429 Meleagris gallopavo
100561439 Anolis carolinensis
100606026 Nomascus leucogenys
100621927 Sus scrofa
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