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ERO1-Like beta (S. Cerevisiae) Proteins (ERO1LB)

Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Additionally we are shipping ERO1-Like beta (S. Cerevisiae) Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat ERO1LB ERO1LB 364755  
ERO1LB 56605 Q86YB8
ERO1LB 67475 Q8R2E9
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Top ERO1-Like beta (S. Cerevisiae) Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ERO1LB Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for ERO1-Like beta (S. Cerevisiae) (ERO1LB) Interaction Partners

Human ERO1-Like beta (S. Cerevisiae) (ERO1LB) interaction partners

  1. glutathione limits Ero1-dependent oxidation in the endoplasmic reticulum

  2. Ero1alpha and Ero1beta are retained in the endoplasmic reticulum by interactions with PDI (show PADI1 Proteins) and ERp44 (show ERP44 Proteins)

  3. the Ero FAD binding domain is critical for conformational stability, allowing Ero proteins to withstand stress conditions that cause client proteins to misfold

  4. The lack of correlation between changes in SAT adiponectin (show ADIPOQ Proteins) gene and protein expression and its circulating levels suggests that adipose tissue synthesis and release of adiponectin (show ADIPOQ Proteins) are highly regulated pathways.

Mouse (Murine) ERO1-Like beta (S. Cerevisiae) (ERO1LB) interaction partners

  1. combined loss-of-function mutations in genes encoding the ER thiol oxidases ERO1alpha, ERO1beta, and PRDX4 (show PRDX4 Proteins) compromised the extracellular matrix and interfered with the intracellular maturation of procollagen

  2. Several lines of evidence suggest that ERO1lbeta is involved in maintaining insulin (show INS Proteins) content of pancreatic beta cells and in regulating beta cell survival during ER oxidative stress.

  3. An unexpectedly selective function for ERO1-beta in oxidative protein folding in insulin (show INS Proteins)-producing cells that is required for glucose homeostasis in vivo.

ERO1-Like beta (S. Cerevisiae) (ERO1LB) Protein Profile

Protein Summary

Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the being a source of oxidative stress. Required for the folding of cell, thereby being a source of oxidative stress.

Gene names and symbols associated with ERO1LB

  • ERO1-like beta (S. cerevisiae) (Ero1lb)
  • ERO1-like beta (S. cerevisiae) (ERO1LB)
  • 1300013B24Rik protein
  • 1700065B09Rik protein
  • AI447560 protein
  • ero1-beta protein
  • RGD1563548 protein

Protein level used designations for ERO1LB

ERO1-like protein beta , ERO1-like beta (S. cerevisiae) , endoplasmic reticulum oxidoreductin 1-Lbeta , ERO1-like protein beta-like , ERO1-L-beta , endoplasmic oxidoreductin-1-like protein B , oxidoreductin-1-L-beta , endoplasmic oxidoreductase 1 beta

GENE ID SPECIES
364755 Rattus norvegicus
421509 Gallus gallus
469720 Pan troglodytes
488956 Canis lupus familiaris
514361 Bos taurus
100410296 Callithrix jacchus
100440749 Pongo abelii
100593455 Nomascus leucogenys
56605 Homo sapiens
67475 Mus musculus
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