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ESX Homeobox 1 Proteins (ESX1)

ESX1 encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. Additionally we are shipping ESX Homeobox 1 Antibodies (43) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ESX1 80712 Q8N693
Mouse ESX1 ESX1 13984  
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Top ESX Homeobox 1 Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ESX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for ESX Homeobox 1 (ESX1) Interaction Partners

Human ESX Homeobox 1 (ESX1) interaction partners

  1. ESX1 mRNA level decreases as the severity of spermatogenic defects increase in non-obstructive azoospermic men.

  2. ESX1 emerges as a potentially reliable molecular marker of residual spermatogenesis in azoospermic men

  3. proteolytic processing of ESXR1 plays a role in concerted regulation of the cell cycle and transcription in human cells

  4. ESX1L is expressed during all stages of placental development and is localized to sparse areas of trophoblast in terminal villi in association with cytotrophoblastic cells

  5. In FGR (show FGR Proteins)-affected placentae, ESX1L levels were lower than in gestation-matched controls, indicating a potential role for the ESX1L gene within the growth control mechanism of the fetus, through its effect on placental function.

Mouse (Murine) ESX Homeobox 1 (ESX1) interaction partners

  1. Use of wild-type and ESX-1-deficient mycobacterial strains demonstrates that mycobacterial type 7 secretion system (T7SS) differentially affects macrophage cell death and interleukin (IL)-1b (show IL1B Proteins) secretion.

  2. ESX1 existed in the testes after 3 weeks of age, coincident with the appearance of round spermatids.ESX1 expression became more abundant in the seminiferous tubules as the development of round spermatids progressed into spermatozoa.

ESX Homeobox 1 (ESX1) Protein Profile

Protein Summary

This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis.

Gene names and symbols associated with ESX Homeobox 1 Proteins (ESX1)

  • ESX homeobox 1 (ESX1)
  • extraembryonic, spermatogenesis, homeobox 1 (Esx1)
  • ESX1L protein
  • ESXR1 protein
  • Spx1 protein

Protein level used designations for ESX Homeobox 1 Proteins (ESX1)

ESX1-related protein , extraembryonic, spermatogenesis, homeobox 1 homolog , homeobox protein ESX1 , extraembryonic spermatogenesis homeobox 1

GENE ID SPECIES
80712 Homo sapiens
13984 Mus musculus
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