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EBF3 encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. Additionally we are shipping EBF3 Antibodies (29) and many more products for this protein.
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EB3 (show MAPRE3 Proteins) binds to IP3 receptors, promotes IP3R (show ITPR1 Proteins) clustering and Ca2 (show CA2 Proteins)+ signals in endothelial cells.
Ebf3 is a new regulator of terminal muscle differentiation in the diaphragm, and Ebf (show EBF1 Proteins) factors cooperate with MyoD (show MYOD1 Proteins) in the induction of muscle-specific (show EIF3K Proteins) genes
The regulation of Ebf3 expression by miR218 controls the terminal differentiation of dopaminergic neurons.
MAP1B interacts directly with EB1 (show MAPRE1 Proteins) and EB3 (show MAPRE3 Proteins) (EBs), two core 'microtubule plus-end tracking proteins' ( TIPs), and sequesters them in the cytosol of developing neuronal cells.
Ebf2 (show EBF2 Proteins) and Ebf3, singly or together, control the migration of Cajal-Retzius cells arising in the cortical hem. These findings provide evidence that Ebfs directly regulate Cajal-Retzius cell development
DDA3 (show PSRC1 Proteins) is a novel microtubule-associated protein (show SPAG5 Proteins) that binds to EB3 (show MAPRE3 Proteins), and results implicate DDA3 (show PSRC1 Proteins) and EB3 (show MAPRE3 Proteins) in the beta-catenin (show CTNNB1 Proteins)-mediated growth signaling.
Two +TIPs, CLIP-170 and end-binding protein 3 (EB3 (show MAPRE3 Proteins)), turn over rapidly on MT ends. Diffusion of CLIP-170 and EB3 (show MAPRE3 Proteins) appears to be rate limiting for their binding to MT plus ends.
Data revealed that expression of DNA binding inhibitor 3, early B cell factor 2, Ebf3, Iroquois related homeobox 1, Kruppel-like factor 7 , mab-21-like 1 , fatty acid binding protein 7 and stathmin-like 4,were enriched in the diencephalon of zebrafish.
Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia (show BCL11A Proteins)
EBF3 (show MAPRE3 Proteins) tumor suppressor is epigenetically silenced and that it serves as an independent prognostic marker in gastric carcinoma.
Results verify IRX1 (show IRX3 Proteins), EBF3 (show MAPRE3 Proteins), SLC5A8, SEPT9 (show SEPT9 Proteins), and FUSSEL18 as valid methylation markers in two separate sets of HNSCC specimens; also preliminarily show a trend between HPV16 positivity and target gene hypermethylation of IRX1 (show IRX3 Proteins), EBF3 (show MAPRE3 Proteins), SLC5A8, and SEPT9 (show SEPT9 Proteins).
Findings suggested that the transfection of EBF3 (show MAPRE3 Proteins) gene into HepG2 induced the cell proliferation from G1 phase to G2 phase by increasing the number of cells.
Expression of EBF3 resulted in cell cycle arrest and apoptosis. EBF3 regulates a transcriptional program underlying a putative tumor suppression pathway.
Frequent methylation of EBF3 (show MAPRE3 Proteins) gene is associated with head and neck squamous cell carcinoma
This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma.
early B-cell factor 3
, Olf-1/EBF-like 2
, transcription factor COE3
, olf-1/EBF-like 2
, EB1 protein family member 3
, end-binding protein 3
, microtubule-associated protein RP/EB family member 3