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Early Growth Response 1 Proteins (EGR1)

The protein encoded by EGR1 belongs to the EGR family of C2H2-type zinc-finger proteins. Additionally we are shipping EGR1 Antibodies (132) and EGR1 Kits (44) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EGR1 1958 P18146
EGR1 13653 P08046
EGR1 24330 P08154
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Top EGR1 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$767.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$876.70
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Serinus canaria His tag   1 mg Log in to see 56 to 66 Days
$2,047.83
Details
Yeast REACT_Zebra finch His tag   1 mg Log in to see 56 to 66 Days
$2,464.00
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,467.67
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,408.17
Details

EGR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)
,
Rat (Rattus)

More Proteins for Early Growth Response 1 (EGR1) Interaction Partners

Pig (Porcine) Early Growth Response 1 (EGR1) interaction partners

  1. Egr-1 silencing through intracoronary delivery of a targeting DNAzyme at the time of reperfusion following acute myocardial ischemia decreases myocardial inflammation and apoptosis leading to improved cardiac function.

  2. Intracoronary delivery of DNAzymes targeting human EGR-1 reduces infarct size following myocardial ischaemia reperfusion.

  3. Data suggest that Egr-1 protein levels may be tightly regulated in an attempt to diminish neurotoxicity or to enhance plasticity in newborn animals.

Human Early Growth Response 1 (EGR1) interaction partners

  1. IL-33 (show IL33 Proteins)-ERK (show EPHB2 Proteins)/JNK (show MAPK8 Proteins)/p38 (show CRK Proteins)/Egr-1/TSLP (show TSLP Proteins) axis involved in allergic skin Th2 inflammation

  2. EGR-1 overexpression in Jurkat cells transfected to express Tax (show CNTN2 Proteins), promoted the activation of several genes, especially those that contained AP-1 (Jun (show JUN Proteins)/c-Fos), but knockdown of endogenous EGR-1 by siRNA reduced Tax (show CNTN2 Proteins)-mediated JNK-1 (show MAPK8 Proteins) transcription.

  3. EGR-1 plays a critical role in LTD4-induced cytokine transcription in Hodgkin cell lines

  4. Data show that cyclooxygenase2 (COX2)overexpression induces prostaglandin E synthase (PTGES (show PTGES Proteins)) through early growth response 1 (EGR1) in colorectal cancer cell lines.

  5. C2238/alphaANP downregulates ApoE (show APOE Proteins) in vascular smooth muscle cells through type C natriuretic peptide receptor-dependent activation of Egr-1 and the consequent upregulation of miR199a.

  6. mPGES-1 (show PTGES Proteins) is downregulated via EGR1 and has a role in caffeine inhibition on PGE2 synthesis of HBx hepatocytes

  7. Egr1 depletion delayed the growth of heterotopically implanted GL261 and HCT116 tumors.

  8. H/R activates ROS (show ROS1 Proteins)/Egr-1 signaling pathway in H9c2 cells, and JNK (show MAPK8 Proteins) activation plays an important role in this pathway

  9. Functional changes of EGR1 (and miR (show MLXIP Proteins)-132) during the course of Alzheimer's disease contribute to late neurodegeneration in the nucleus basalis of Meynert.

  10. Data show that that the nanopore can detect and discriminate both specific and nonspecific binding conformations of early growth response 1 protein zif268 on DNA.

Cow (Bovine) Early Growth Response 1 (EGR1) interaction partners

  1. Chronic hypoxia induces Egr-1 via activation of ERK1/2 and contributes to pulmonary vascular remodeling.

  2. The authors conclude that Egr-1 protein expression is very sensitive to upregulation by hypoxia in pulmonary artery adventitial fibroblasts and that it plays an important role in the autonomous growth phenotype induced by hypoxia in these cells.

  3. EGR-1's expression prior to ovulation and its stimulating effect on the expression of genes known to be involved in prostaglandin biosynthesis pathway, suggest its potential involvement in the regulation of preovulatory events in cattle.

Mouse (Murine) Early Growth Response 1 (EGR1) interaction partners

  1. EGR1, an early growth response factor, is a critical transcription factor that regulates the hepatic clock circuit.

  2. EGR1(-/-) mouse embryonic fibroblasts demonstrated lower susceptibility to Venezuelan equine encephalitis virus-induced cell death than isogenic wild-type fibroblasts, indicating that EGR1 modulates proapoptotic pathways following virus infection.

  3. The levels of B23 (show NPM1 Proteins) expression are directly regulated by EGR1.

  4. our data demonstrate that the effect of FGF23 (show FGF23 Proteins) on Pi homeostasis is mediated, at least in part, by activation of egr-1.

  5. associated with this behavior, that is, an increase in the expression of the immediate early (show JUN Proteins) gene Early Growth Response protein 1 (EGR1, Zif268)

  6. Egr-1 is involved in NMDAR (show GRIN1 Proteins)-mediated PSD-95 (show DLG4 Proteins) down-regulation and AMPAR endocytosis, a process important in the expression of long term depression

  7. ERG1 (show KCNH2 Proteins) overexpression led to the development of highly aggressive B-cell malignancies.

  8. EGR-1-induced GGPPS (show GGPS1 Proteins) plays a vital role in the liver regeneration through the RAS/MAPK (show MAPK1 Proteins) signaling.

  9. Egr1 plays an important role in ischemia-reperfusion injury in lung transplants by regulating polymorphonuclear neutrophil infiltration.

  10. Study indicated that ischemia-induced EGR1 expression may exaggerate brain injury by reducing BDNF (show BDNF Proteins) expression

Zebrafish Early Growth Response 1 (EGR1) interaction partners

  1. egr1 colocalizes with tyrosine hydroxylase (show TH Proteins) in the olfactory bulb throughout brain development.

  2. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  3. The cDNA coding for zebrafish Egr1 was obtained and its expression pattern was examined during zebrafish embryogenesis using whole-mount in situ hybridization

  4. Egr1 gene has important role in zebrafish embryonic oculogenesis. Lens and retina with egr1 gene deletion were primitive and lacked differentiation. Such arrested retinal and lenticular development in Egr1 morphants resulted in microphthalmos.

Rabbit Early Growth Response 1 (EGR1) interaction partners

  1. Gene therapy using in vivo transfection of an Egr-1 decoy ODN significantly inhibits proliferation of VSMC and intimal hyperplasia of vein grafts in a rabbit model.

  2. Results show that EGR1 plays a key role in tendon formation, healing, and repair through BMP12 (show GDF7 Proteins)/Smad1 (show SMAD1 Proteins)/5/8 pathway.

  3. Collectively, these results demonstrate that Egr-1 is expressed rapidly upon HSV-1 infection and that this novel induction could be due to the NFsmall ka, CyrillicB/CREB (show CREB1 Proteins)-mediated transactivation.

EGR1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

Gene names and symbols associated with Early Growth Response 1 Proteins (EGR1)

  • early growth response protein 1(Egr-1, NGFI-A) (EGR-1)
  • early growth response protein 1 (egr-1) (CNK00890)
  • early growth response 1 (EGR1)
  • early growth response 1 (Egr1)
  • early growth response 1 (egr1)
  • early growth response 1 (egr1-a)
  • early growth response protein 1 (EGR-1)
  • A530045N19Rik protein
  • at225 protein
  • egr protein
  • egr-1 protein
  • EGR-1-A protein
  • EGR1 protein
  • ETR103 protein
  • g0s30 protein
  • Krox-1 protein
  • krox-24 protein
  • krox24 protein
  • Ngf1 protein
  • NGF1-A protein
  • Ngfi protein
  • ngfi-a protein
  • NGFIA protein
  • tis8 protein
  • wu:fj64b05 protein
  • wu:fq25f01 protein
  • Xegr-1 protein
  • zenk protein
  • Zfp-6 protein
  • zif-268 protein
  • Zif268 protein
  • znf225 protein

Protein level used designations for Early Growth Response 1 Proteins (EGR1)

early growth response protein 1(Egr-1, NGFI-A) , early growth response protein 1 (egr-1) , early growth response 1 , EGR-1 , early growth response protein 1 , nerve growth factor-induced protein A , transcription factor ETR103 , transcription factor Zif268 , zinc finger protein 225 , zinc finger protein Krox-24 , Krox-24 nuclear protein , zinc finger protein ZENK , etID309970.14 , zinc-finger transcriptional protein , early growth response protein 1-A

GENE ID SPECIES
397332 Sus scrofa
3254484 Cryptococcus neoformans var. neoformans JEC21
100618969 Monodelphis domestica
1958 Homo sapiens
481528 Canis lupus familiaris
407125 Bos taurus
13653 Mus musculus
24330 Rattus norvegicus
462097 Pan troglodytes
100716298 Cavia porcellus
100520726 Sus scrofa
373931 Gallus gallus
443547 Ovis aries
30498 Danio rerio
100008579 Taeniopygia guttata
399162 Xenopus laevis
100009491 Oryctolagus cuniculus
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