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Early Growth Response 2 Proteins (EGR2)

The protein encoded by EGR2 is a transcription factor with three tandem C2H2-type zinc fingers. Additionally we are shipping EGR2 Antibodies (92) and EGR2 Kits (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EGR2 1959 P11161
EGR2 13654 P08152
EGR2 114090 P51774
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Top EGR2 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Cricetulus griseus His tag   1 mg Log in to see 56 to 66 Days
$2,057.00
Details
Yeast REACT_Guppy His tag   1 mg Log in to see 56 to 66 Days
$2,057.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,325.67
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,327.50
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$952.01
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

EGR2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Early Growth Response 2 (EGR2) Interaction Partners

Human Early Growth Response 2 (EGR2) interaction partners

  1. EGR2 mutation presents as an axonal Charcot-Marie-Tooth phenotype with variable severity.

  2. MicroRNA20a promotes the proliferation and cell cycle of human osteosarcoma cells by suppressing EGR2 expression.

  3. These results suggested that EGR2 overexpression has a pivotal role in the downregulation of cytokines implicated in the pathophysiology of Guillain-Barre syndrome

  4. A recurrent mutation was identified in EGR2 which appears to be associated with the pathogenesis of schizophrenia.

  5. Knock-down of EGR2 with siRNA was demonstrated to have a similar effect as the over-expression of miR (show MLXIP Proteins)-330-3p in NSCLC cell lines

  6. Dysregulated Egr-2 is observed in some human autoimmune disorders.

  7. EGR2 knockdown inhibited proliferation, clonogenicity and spheroidal growth in vitro and induced regression of Ewing sarcoma xenografts.

  8. our data suggest that robust CD26 (show DPP4 Proteins) costimulatory signaling induces preferential expression of EGR2 and IL-10 (show IL10 Proteins) as a potential mechanism for regulating CD26 (show DPP4 Proteins)-mediated activation.

  9. Overexpression of EGR2 significantly attenuated the oncogenic effect of miR (show MLXIP Proteins)-20a.

  10. Lack of association of EGR2 variants with bipolar disorder in Japanese population.

Mouse (Murine) Early Growth Response 2 (EGR2) interaction partners

  1. Mir106b regulates pro-allergic properties of dendritic cells and Th2 polarisation by targeting Egr-2 in vitro

  2. let-7 miRNAs promote expression of the myelination-driving master transcription factor Krox20

  3. The data suggest that Pak2 (show PAK2 Proteins) controls thymic Natural Killer T-cell development by providing a signal that links Egr2 to induce PLZF (show ZBTB16 Proteins), in part by regulating signaling lymphocyte activation molecule (show SLAMF1 Proteins) 6 expression.

  4. demonstrate a novel function of EGR2/3 that is important for Tfh cell development and Tfh cell-mediated B cell immune responses

  5. Egr-2 was upregulated by NF-kappaB (show NFKB1 Proteins) activation in p50 (show LSP1 Proteins)+/+ hippocampal slices.

  6. During heart valve development, Krox20-mediated activation of fibrillar Col1a1 (show COL1A1 Proteins) and Col3a1 (show COL3A1 Proteins) genes is crucial to avoid postnatal degeneration of the aortic valve leaflets.

  7. EGR2 promotes peripheral naive T-cell differentiation, with delayed T-cell receptor-induced proliferation in naive T cells from Egr2 conditional knockout mice, and decreased production of cytokines in cells subjected to T-helper differentiation.

  8. A direct, positive autoregulatory loop amplifies and maintains the expression of Krox20, a transcription factor governing vertebrate hindbrain segmentation.

  9. The results indicated a novel role for Egr2 in repressing adipocyte lineage commitment and promoting early smooth muscle-like cell differentiation.

  10. These findings support a model in which Egr2-neurons are a critical component of the respiratory chemoreflex into adulthood.

Zebrafish Early Growth Response 2 (EGR2) interaction partners

  1. A direct, positive autoregulatory loop amplifies and maintains the expression of Krox20, a transcription factor governing vertebrate hindbrain segmentation.

  2. Hindbrain patterning requires fine-tuning of early krox20 transcription by Sprouty 4.

  3. Data show that Irx7 and Irx1b are required for the proper formation and specification of rhombomeres 1 to 4, and that Irx7 functionally interacts with Meis1.1 (show MEIS1 Proteins) to activate the expression of anterior hindbrain markers, such as krox20.

EGR2 Protein Profile

Protein Summary

The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with Early Growth Response 2 Proteins (EGR2)

  • early growth response 2 (EGR2)
  • early growth response 2 (Egr2)
  • early growth response 2b (egr2b)
  • AT591 protein
  • cb427 protein
  • CMT1D protein
  • CMT4E protein
  • Egr-2 protein
  • egr2 protein
  • id:ibd5073 protein
  • Krox-20 protein
  • krox20 protein
  • KRX-20 protein
  • krx20 protein
  • NGF1-B protein
  • wu:fb71h10 protein
  • Zfp-6 protein
  • Zfp-25 protein
  • zgc:92210 protein

Protein level used designations for Early Growth Response 2 Proteins (EGR2)

E3 SUMO-protein ligase EGR2 , KROX-20, Drosophila, homolog (early growth response-2) , early growth response protein 2 , zinc finger protein Krox-20 , early growth response 2 (Krox-20 homolog, Drosophila) , EGR-2 , EGR-2b , early growth response protein 2b , krox-20 , protein krx-20

GENE ID SPECIES
1959 Homo sapiens
479219 Canis lupus familiaris
100038004 Sus scrofa
13654 Mus musculus
114090 Rattus norvegicus
100721167 Cavia porcellus
100297981 Bos taurus
101122407 Ovis aries
30190 Danio rerio
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