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anti-Ectodysplasin A Receptor (EDAR) Antibodies

EDAR encodes a member of the tumor necrosis factor receptor family. Additionally we are shipping EDAR Proteins (19) and EDAR Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EDAR 10913 Q9UNE0
EDAR 13608 Q9R187
EDAR 365581  
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Top anti-EDAR Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.39 KDa) . 200 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB Ectodysplasin A Receptor antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$383.17
Details
Human Rabbit Un-conjugated IHC (p)   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 14 Days
$527.15
Details
Human Rat Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$555.50
Details
Human Mouse Un-conjugated ELISA, WB EDAR polyclonal antibody (A01), Lot # 050921JC01. Western Blot analysis of EDAR expression in Daoy. Western Blot detection against Immunogen (38.76 KDa) . 50 μL Log in to see 9 Days
$298.57
Details

EDAR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-EDAR Antibodies

  1. Chicken Polyclonal EDAR Primary Antibody for WB - ABIN2773948 : RamaDevi, Reddy, Ranjan, Bashyam: Molecular genetic analysis of patients from India with hypohidrotic ectodermal dysplasia reveals novel mutations in the EDA and EDAR genes. in The British journal of dermatology 2007 (PubMed)

More Antibodies against EDAR Interaction Partners

Medaka Ectodysplasin A Receptor (EDAR) interaction partners

  1. These data suggest differential roles for Eda (show EDA Antibodies)-Edar signaling in the induction and growth of scales and teeth and support the intrinsic odontogenic competence of the rostral endoderm in medaka.

Zebrafish Ectodysplasin A Receptor (EDAR) interaction partners

  1. Eda (show EDA Antibodies) and edar are not required for early development but are specific for the development of adult skeletal and dental structures.

Human Ectodysplasin A Receptor (EDAR) interaction partners

  1. Four traits of ear pinna anatomic variation are associated with a functional variant in the EDAR gene, a key regulator of embryonic skin appendage development.

  2. Individuals with a c.1072C > T mutation in the EDAR-gene displayed more hair shaft deformations confirming the role of EDAR for human hair follicle development and postnatal hair follicle cycling.

  3. Individuals with a c.1072C > T mutation in the EDAR-gene displayed a typical pattern of congenitally missing teeth in the frontal area with functional consequences.

  4. Using whole-exome sequencing we describe a novel homozygous missense mutation in EDAR causing autosomal recessive HED (show EDA Antibodies) associated with palmoplantar hyperkeratosis and the absence of breasts.

  5. Study generated a knockin mouse model and found that, as in humans, hair thickness is increased in EDAR370A mice; new biological targets affected by the mutation were identified, including mammary and eccrine glands. Building on these results EDAR370A was found to be associated with an increased number of active eccrine glands in the Han Chinese.

  6. This is the first report of a founder EDAR mutation and of a significantly high frequency of autosomal recessive HED (show EDA Antibodies).

  7. WNT10A (show WNT10A Antibodies) and EDAR were each responsible for 16% of hypohidrotic/anhidrotic ectodermal dysplasia cases.

  8. screening of all the 12 exons and splice junctions of gene EDAR revealed a novel missense mutation (c.1163T>C; p.Ile388Thr) in family A and a novel insertion mutation (c.1014insA; p.V339SfsX6) in family B.

  9. Data show that 25 different mutations on EDA (show EDA Antibodies) and EDAR genes were detected in HED (show EDA Antibodies) patients.

  10. a novel compound heterozygous mutation [c.52-2A>G; c.212G>A (p.Cys71Tyr)]; significance of the EDAR signalling pathway in the ectodermal morphogenesis.

Mouse (Murine) Ectodysplasin A Receptor (EDAR) interaction partners

  1. Edar is expressed in the developing ear. Edar-deficient mice have an abnormally shaped pinna.

  2. Edar signalling has pleiotropic effects on craniofacial and cutaneous glands

  3. Edar expression is confined to the ectoderm and occurs in a pattern that suggests a role of ectodysplasin/Edar signaling in the interactions between the ectodermal compartments and the formation and function of hair placodes.

  4. Analysis of expression patterns of eda (show EDA Antibodies), edar and tnfrsf19 (show TNFRSF19 Antibodies) in mouse embryogenesis.

  5. Data show that Edar misexpression disrupts tooth patterning and differentiation.

  6. isoforms of EDA (show EDA Antibodies)-A5 and A5',activated NF-kappaB (show NFKB1 Antibodies) through receptors EDAR and XEDAR (show EDA2R Antibodies)

  7. demonstrate that epidermal NF-kappaB (show NFKB1 Antibodies) activity is first observed in placodes of primary guard hair follicles at day E14.5, and that in vivo NF-kappaB (show NFKB1 Antibodies) signalling is activated downstream of Eda A1 (show EDA Antibodies) and EdaR

  8. Data show that ectodysplasin receptor (Edar)-bone morphogenetic protein (BMP)-4 and -7 signaling and transcriptional interactions are central to generation of the primary hair follicle pattern.

  9. Thus, our data demonstrate that in addition to its well-established role in HF morphogenesis, Edar signaling is also involved in hair cycle control and regulates apoptosis in HF keratinocytes during catagen.

  10. Microarray profiling of genes differentially regulated by short exposure to recombinant Eda-A1 (show EDA Antibodies) in embryonic eda (show EDA Antibodies)(-/-) skin explants, was performed to identify direct targets of ectodysplasin pathway.

EDAR Antigen Profile

Protein Summary

This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Gene names and symbols associated with EDAR

  • ectodysplasin-A receptor (edar) antibody
  • ectodysplasin receptor (edar) antibody
  • ectodysplasin A receptor (edar) antibody
  • ectodysplasin A receptor (EDAR) antibody
  • ectodysplasin-A receptor (Edar) antibody
  • dl antibody
  • ECTD10A antibody
  • ECTD10B antibody
  • ED1R antibody
  • ED3 antibody
  • ED5 antibody
  • EDA-A1R antibody
  • EDA1R antibody
  • EDA3 antibody
  • EDAR antibody
  • HRM1 antibody
  • MGC88893 antibody
  • RGD1561714 antibody
  • rs3 antibody

Protein level used designations for EDAR

RS-3 , protein reduced scale-3 , tumor necrosis factor receptor superfamily member EDAR , ectodysplasin receptor , finless , fls , ectodysplasin A receptor , tumor necrosis factor receptor superfamily member EDAR-like , EDA-A1 receptor , anhidrotic ectodysplasin receptor 1 , downless homolog , downless, mouse, homolog of , ectodermal dysplasia receptor , ectodysplasin 1, anhidrotic receptor , ectodysplasin-A receptor , ectodysplasin A1 receptor , downless

GENE ID SPECIES
100049352 Oryzias latipes
100174891 Gasterosteus aculeatus
796370 Danio rerio
735810 Pan troglodytes
448544 Xenopus (Silurana) tropicalis
100060614 Equus caballus
695059 Macaca mulatta
100387176 Callithrix jacchus
100432950 Pongo abelii
10913 Homo sapiens
428015 Gallus gallus
481305 Canis lupus familiaris
613947 Bos taurus
13608 Mus musculus
365581 Rattus norvegicus
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