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Ectodysplasin A2 Receptor Proteins (EDA2R)

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Additionally we are shipping Ectodysplasin A2 Receptor Antibodies (90) and Ectodysplasin A2 Receptor Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EDA2R 60401 Q9HAV5
EDA2R 245527 Q8BX35
EDA2R 296872  
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Top Ectodysplasin A2 Receptor Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK-293 Human Fc Tag   0.1 mg Log in to see 2 to 3 Days
$515.63
Details
HOST_Human Mouse His tag   10 μg Log in to see 5 Days
$121.00
Details

EDA2R Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
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Mouse (Murine) , , ,
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Rat (Rattus)
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Top referenced Ectodysplasin A2 Receptor Proteins

  1. Human Ectodysplasin A2 Receptor Protein expressed in Human Cells - ABIN2004835 : Yan, Wang, Hymowitz, Schilbach, Lee, Goddard, de Vos, Gao, Dixit: Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors. in Science (New York, N.Y.) 2000 (PubMed)
    Show all 3 references for ABIN2004835

  2. Mouse (Murine) Ectodysplasin A2 Receptor Protein expressed in Human Cells - ABIN2007764 : Sinha, Zachariah, Quiñones, Shindo, Chaudhary: Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor. in The Journal of biological chemistry 2002 (PubMed)
    Show all 3 references for ABIN2007764

  3. Rat (Rattus) Ectodysplasin A2 Receptor Protein expressed in Human Cells - ABIN2009308 : Prodi, Pirastu, Maninchedda, Sassu, Picciau, Palmas, Mossa, Persico, Adamo, Angius, Pirastu: EDA2R is associated with androgenetic alopecia. in The Journal of investigative dermatology 2008 (PubMed)
    Show all 3 references for ABIN2009308

More Proteins for Ectodysplasin A2 Receptor (EDA2R) Interaction Partners

Human Ectodysplasin A2 Receptor (EDA2R) interaction partners

  1. XEDAR activates the non-canonical NF-kappaB (show NFKB1 Proteins) pathway.

  2. To investigate the evolutionary history of the EDA2R/AR intergenic region, we characterized the haplotype structure of 52 of its highly differentiated SNPs. Nearly all human X chromosomes carry one of two modal haplotypes for these 52 SNPs.

  3. The results suggest that EDA2R confers susceptibility to early onset female pattern hair loss

  4. A crucial role of the EDA-A2 (show EDA Proteins)/ectodysplasin A2 (XEDAR) interaction is revealed in the p53 (show TP53 Proteins)-signaling pathway.

  5. because no frequent variant other than rs1385699 has been reported in EDA2R in the European population, it is probable that the causative variant(s) modifies the expression of one or more flanking genes, i.e. AR and EDA2R

  6. Results establish a major role of TRAF3 (show TRAF3 Proteins) and -6 in X-linked ectodermal dysplasia receptor (show EDAR Proteins) (XEDAR) signaling and in the process of ectodermal differentiation.

  7. XEDAR belongs to a novel class of death receptors that lack a discernible death domain but are capable of activating apoptosis in a caspase 8- and FADD-dependent fashion

  8. isoforms of EDA (show EDA Proteins)-A5 and A5',activated NF-kappaB (show NFKB1 Proteins) through receptors EDAR (show EDAR Proteins) and XEDAR

  9. The androgen receptor (show AR Proteins) gene and EDA2R are significantly associated with androgenetic alopecia.

  10. androgen receptor (show AR Proteins)/ectodysplasin A2 receptor haplotype may have a role in male pattern baldness

Mouse (Murine) Ectodysplasin A2 Receptor (EDA2R) interaction partners

  1. EDA-A2 (show EDA Proteins) transgenic mice exhibited multifocal myodegeneration; this phenotype was not observed in the absence of XEDAR

  2. isoforms of EDA (show EDA Proteins)-A5 and A5',activated NF-kappaB (show NFKB1 Proteins) through receptors EDAR (show EDAR Proteins) and XEDAR

Ectodysplasin A2 Receptor (EDA2R) Protein Profile

Protein Summary

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with EDA2R

  • ectodysplasin A2 receptor (EDA2R)
  • ectodysplasin A2 receptor (LOC100222733)
  • ectodysplasin A2 receptor (Eda2r)
  • 9430060M22Rik protein
  • EDA-A2R protein
  • EDAA2R protein
  • RGD1564025 protein
  • TNFRSF27 protein
  • Xedar protein

Protein level used designations for EDA2R

X-linked ectodysplasin receptor , tumor necrosis factor receptor superfamily member 27 , xedar , ectodysplasin A2 receptor , EDA-A2 receptor , X-linked ectodysplasin-A2 receptor , tumor necrosis factor receptor superfamily member XEDAR , X linked ectodysplasin receptor , ectodysplasin A2 isoform receptor

GENE ID SPECIES
473648 Pan troglodytes
422166 Gallus gallus
710244 Macaca mulatta
100222733 Taeniopygia guttata
60401 Homo sapiens
245527 Mus musculus
296872 Rattus norvegicus
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