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ENTPD3 is similar to E-type nucleotidases (NTPases). Additionally we are shipping Ectonucleoside Triphosphate diphosphohydrolase 3 Proteins (6) and Ectonucleoside Triphosphate diphosphohydrolase 3 Kits (1) and many more products for this protein.
Showing 10 out of 59 products:
Human Polyclonal ENTPD3 Primary Antibody for EIA, FACS - ABIN951308
Fausther, Pelletier, Ribeiro, Sévigny, Picher: Cystic fibrosis remodels the regulation of purinergic signaling by NTPDase1 (CD39) and NTPDase3. in American journal of physiology. Lung cellular and molecular physiology 2010
Show all 4 references for ABIN951308
expressed in zebrafish hypocretin (show OX Antibodies) cells as previously reported in mammals, also in the cranial nerves (gV, gVII, gIV (show CCDC88A Antibodies) and gX) and in primary sensory neurons (i.e., Rohon-Beard neurons) in the spinal cord
Despite the increased level of NTPDase1 (show ENTPD1 Antibodies) and NTPDase3 mRNA expression in chondrogenically induced MSCs, their activity toward ATP remains quite low.
NTPDase3 is the major ectonucleotidase in pancreatic beta-cells in multiple species and modulates insulin (show INS Antibodies) secretion by controlling activation of purinergic receptors.
Cystic fibrosis (show S100A8 Antibodies) epithelia exhibit >50% lower NTPDase1 (show ENTPD1 Antibodies) activity, protein, and mRNA levels than normal epithelia, whereas these parameters are threefold higher for NTPDase3.
NTPDase3 sequence revealed a high degree of structural fold similarity with a bacterial exopolyphosphatase
efficiently inhibit the NTPDase3expressed in insulin (show INS Antibodies) secreting human pancreatic islet cells in situ
Generation of a helical model for NTPDase3 suggests the importance of putative hydrogen bond interactions of conserved polar residues which are critical for enzyme expression, activity, and its susceptibility to membrane perturbations.
The results of this study proposeed that NTPDase3 is a key regulator of nociceptive signaling that also makes an unexpected contribution to innocuous tactile sensation.
the specific localization of NTPDase3 in the digestive system suggests functional roles of the enzyme, in association with NTPDase2 (show ENTPD2 Antibodies) and ecto-5'-nucleotidase (show ACPP Antibodies), in epithelial functions such as secretion and in enteric neurotransmission.
ENTPD3 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD3 contains 4 apyrase-conserved regions which is characteristic of NTPases.
ectonucleoside triphosphate diphosphohydrolase 3
, ecto-nucleosidase triphosphate diphosphohydrolase 3
, ecto-nucleoside triphosphate diphosphohydrolase 3
, ectonucleoside triphosphate diphosphohydrolase 3-like
, CD39 antigen-like 3
, CD39-like 3
, NTPDase 3
, ecto-ATP diphosphohydrolase 3
, ecto-ATPDase 3
, ecto-ATPase 3
, ecto-apyrase 3