You are viewing an incomplete version of our website. Please click to reload the website as full version.

Ectonucleotide Pyrophosphatase/phosphodiesterase 1 Proteins (ENPP1)

ENPP1 is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. Additionally we are shipping ENPP1 Antibodies (137) and ENPP1 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ENPP1 5167 P22413
ENPP1 18605  
ENPP1 85496 Q924C3
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top ENPP1 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$841.50
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$873.40
Details
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 11 to 13 Days
$926.20
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details

ENPP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
, ,
Rat (Rattus)

More Proteins for Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) Interaction Partners

Zebrafish Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) interaction partners

  1. enpp1 can exert its function in tissues that are remote from its site of expression.

Human Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) interaction partners

  1. A rare type of idiopathic infantile arterial calcification resulting from a mutation in the gene encoding for the ENPP1 enzyme.

  2. Loss of function mutation in ENPP1 is associated with early onset hearing loss in autosomal recessive hypophosphatemic rickets.

  3. ENPP1 was also identified as a substrate of the 26S proteasome (show Psmd4 Proteins), the activity of which is downregulated in CSCs

  4. Expression of NPP1 and 5'-nucleotidase (show NT5E Proteins) by valve interstitial cells promotes the mineralization of the aortic valve through A2aR (show ADORA2A Proteins) and a cAMP/PKA/CREB (show CREB1 Proteins) pathway.

  5. ENPP1 rs1805101 polymorphism is associated with Insulin (show INS Proteins) resistance and advanced Diabetic nephropathy.

  6. the ENPP1 K121Q polymorphism is associated with insulin (show INS Proteins) resistance during web-based lifestyle intervention, and the K121 allele has a beneficial effect of weight loss on insulin (show INS Proteins) resistance.

  7. In pregnant women, association of both pre-gestational BMI and age with AA homozygous ENPP1 genotype increased significantly the risk of positive oral glucose tolerance test.

  8. this study identified only 1 mutation in ENPP1 in the Chinese pseudoxanthoma elasticum population

  9. EphA3 (show EPHA3 Proteins) was induced by PC-1 (show PCSK1 Proteins) and contributed to the malignant progression of prostate cancer

  10. patterns were confirmed in human teeth, including widespread TNAP (show ALPL Proteins), and NPP1 restricted to cementoblasts lining acellular cementum

Mouse (Murine) Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1) interaction partners

  1. Vitamin D3 regulates Enpp1 expression, which presumably, in the context of adequate tissue non-specific alkaline phosphatase activity, provides phosphate to stimulate mineralisation.

  2. ENPP1-Fc fusion protein prevents the mortality, vascular calcifications and sequela of disease in mouse models of generalized arterial calcification of infancy.

  3. Expression of NPP1 and 5'-nucleotidase (show ACPP Proteins) by valve interstitial cells promotes the mineralization of the aortic valve through A2aR (show ADORA2A Proteins) and a cAMP/PKA/CREB (show CREB1 Proteins) pathway.

  4. Increased NPP1 expression and activity might contribute to the decreased mineralisation observed when osteoblasts are exposed to acid conditions.

  5. NPP1 has a role in obesity and diabetes in a mouse model

  6. we have characterized the phenotypic and histopathologic features of this spontaneous mutant mouse, designated as asj (show ARSJ Proteins)-2J, and we have identified a large deletion/insertion mutation in the Enpp1 gene

  7. these data highlight the key role of NPP1 in regulating calcification of both soft and skeletal tissues.

  8. ENPP1 2'3'-cGAMP-hydrolyzing activity is repsonsible for tumor progression in humans and mice.

  9. Both mono-allelic and bi-allelic ENPP1 deficiency promote dysregulated VSMC function, with robust C/EBP homologous protein (show DDIT3 Proteins) expression and enhanced neointimal hyperplasia after injury in vivo, but marked post-injury calcification limited to Enpp1-/- mice.

  10. Studied the role of genetic modulation and the role of diet in nephrocalcinosis using two established mouse models of ectopic mineralization, Abcc6 (show ABCC6 Proteins)(tm1Jfk) and Enpp1(asj (show ARSJ Proteins)) mice.

ENPP1 Protein Profile

Protein Summary

This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.

Gene names and symbols associated with ENPP1

  • ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1)
  • ectonucleotide pyrophosphatase/phosphodiesterase 1 (enpp1)
  • ectonucleotide pyrophosphatase/phosphodiesterase 1 (Enpp1)
  • 4833416E15Rik protein
  • AI428932 protein
  • ARHR2 protein
  • C76301 protein
  • CD203c protein
  • E-NPP1 protein
  • ENPP1 protein
  • Ly-41 protein
  • M6S1 protein
  • NPP1 protein
  • Npps protein
  • PC-1 protein
  • Pc1 protein
  • Pca protein
  • Pca-1 protein
  • PCA1 protein
  • Pdnp1 protein
  • si:ch211-142e24.2 protein
  • ttw protein
  • twy protein
  • zgc:136238 protein

Protein level used designations for ENPP1

ectonucleotide pyrophosphatase/phosphodiesterase 1 , dgf , ectonucleotide pyrophosphatase/phosphodiesterase family member 1 , ectonucleotidase enpp1 , E-NPP 1 , Ly-41 antigen , alkaline phosphodiesterase 1 , membrane component chromosome 6 surface marker 1 , membrane component, chromosome 6, surface marker 1 , phosphodiesterase I/nucleotide pyrophosphatase 1 , plasma-cell membrane glycoprotein 1 , plasma-cell membrane glycoprotein PC-1 , 1 ectonucleotide pyrophosphatase/phosphodiesterase 1 , lymphocyte antigen 41 , phosphodiesterase I/nucleotide pyrophosphatase 1; 1 ectonucleotide pyrophosphatase/phosphodiesterase 1 , tiptoe walking

GENE ID SPECIES
100073097 Equus caballus
426929 Gallus gallus
463002 Pan troglodytes
562399 Danio rerio
615535 Bos taurus
100137399 Papio anubis
100422807 Xenopus (Silurana) tropicalis
100462923 Xenopus laevis
100562666 Anolis carolinensis
5167 Homo sapiens
18605 Mus musculus
85496 Rattus norvegicus
100009517 Oryctolagus cuniculus
476153 Canis lupus familiaris
100037271 Sus scrofa
Selected quality suppliers for ENPP1 Proteins (ENPP1)
Did you look for something else?