You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) Antibodies

The protein encoded by ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. Additionally we are shipping ENPP2 Kits (16) and ENPP2 Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ENPP2 5168 Q13822
ENPP2 18606 Q9R1E6
ENPP2 84050 Q64610
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-ENPP2 Antibodies at antibodies-online.com

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of anti-ENPP2 Antibody (Center K416) (ABIN389374) in Y79 cell line lysates (35 µg/lane).ENPP2(arrow) was detected using the purified polyclonal antibody. Western blot analysis of anti-ENPP2 Antibody (Center K416) (ABIN389374) in mouse cerebellum tissue lysates (35 µg/lane).ENPP2(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of ENPP2 Antibody (Center) (ABIN650746) in mouse cerebellum tissue lysates (35 µg/lane). ENPP2 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of ENPP2 (arrow) using rabbit polyclonal ENPP2 Antibody (Center) (ABIN650746). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ENPP2 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB (LEFT) Western blot analysis of ENPP2 Antibody (Center) in mouse cerebellum tissue lysates (35ug/lane). ENPP2 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of ENPP2 (arrow) using rabbit polyclonal ENPP2 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ENPP2 gene (Lane 2) (Origene Technologies). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ENPP2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: COLO205 cell lysate WB Suggested Anti-ENPP2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: COLO205 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$533.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colorectal cancer labeled with Anti-Anei-ATX/Autotaxin Polyclonal Antibody, Unconjugated (ABIN740265) followed by conjugation to the secondary antibody Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-Anei-ATX/Autotaxin Polyclonal Antibody, Unconjugated (ABIN740265) at 1:200 followed by conjugation to the secondary antibody 100 μL Log in to see 3 to 7 Days
$269.50
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$218.90
Details
Human Rabbit Un-conjugated ICC, IF, WB WB Image Autotaxin antibody detects ENPP2 protein by Western blot analysis. A. 30 µg U87-MG whole cell lysate/extract 5 % SDS-PAGE Autotaxin antibody , dilution: 1:1000 ICC/IF Image Autotaxin antibody detects Autotaxin protein at cytoplasm by immunofluorescent analysis. Sample: SK-N-SH cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Autotaxin protein stained by Autotaxin antibody , diluted at 1:500. Blue: Hoechst 33342 staining. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining; Read the data in Microplate Reader by 450nm 100 μL Log in to see 3 to 7 Days
$269.50
Details

ENPP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, ,

, , , , , , , , , , , , , , , , ,
Mouse (Murine) , , ,


, , , , , , , , , , , , ,
Rat (Rattus) , ,


, , , , , , , , , , ,

Top referenced anti-ENPP2 Antibodies

  1. Human Polyclonal ENPP2 Primary Antibody for EIA, WB - ABIN358034 : Kawagoe, Soma, Goji, Nishimura, Narita, Inazawa, Nakamura, Sano: Molecular cloning and chromosomal assignment of the human brain-type phosphodiesterase I/nucleotide pyrophosphatase gene (PDNP2). in Genomics 1996 (PubMed)
    Show all 3 references for ABIN358034

  2. Human Polyclonal ENPP2 Primary Antibody for EIA, WB - ABIN453640 : Nam, Clair, Kim, McMarlin, Schiffmann, Liotta, Stracke: Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor. in Cancer research 2001 (PubMed)
    Show all 3 references for ABIN453640

  3. Mouse (Murine) Polyclonal ENPP2 Primary Antibody for ELISA - ABIN2001293 : Boucher, Quilliot, Pradères, Simon, Grès, Guigné, Prévot, Ferry, Boutin, Carpéné, Valet, Saulnier-Blache: Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expression. in Diabetologia 2005 (PubMed)
    Show all 2 references for ABIN2001293

  4. Human Polyclonal ENPP2 Primary Antibody for EIA, WB - ABIN265084 : Murata, Lee, Clair, Krutzsch, Arestad, Sobel, Liotta, Stracke: cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases. in The Journal of biological chemistry 1994 (PubMed)
    Show all 2 references for ABIN265084

More Antibodies against ENPP2 Interaction Partners

Xenopus laevis Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) interaction partners

  1. Defects in forebrain development during loss-of-function experiments for ENPP2, an enzyme involved in the synthesis of extracellular lysophosphatidic acid.

Human Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) interaction partners

  1. autotaxin (ATX), is an ecto (show TRIM33 Antibodies)-lysophospholipase (show PLA2G4A Antibodies) D encoded by the human ENNP2 gene

  2. Altered expression of ENPP2 is associated with various diseases, such as, inflammation, cancer, fibrosis, rheumatoid arthritis and neural tube defects. (Review)

  3. Serum ATX correlates with and predicts measures of glucose homeostasis and insulin (show INS Antibodies) sensitivity in older humans, suggesting that it may be a potential pathogenic factor and/or diagnostic/therapeutic target for insulin (show INS Antibodies) resistance in this population

  4. ATX was induced in monocytic THP-1 (show GLI2 Antibodies) cells by TLR4 (show TLR4 Antibodies) ligand lipopolysaccharide (LPS (show IRF6 Antibodies)), TLR9 (show TLR9 Antibodies) ligand CpG oligonucleotide, and TLR3 (show TLR3 Antibodies) ligand poly(I:C), respectively

  5. Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer

  6. The results are discussed in terms of ATX regulation in wound healing and cancer.We, therefore, demonstrate the concept that accumulation of LPA in the circulation decreases ATX production

  7. Increased serum autotaxin activity represents a highly sensitive, specific and robust diagnostic marker of Intrahepatic cholestasis of pregnancy , distinguishing ICP from other pruritic disorders of pregnancy and pregnancy-related liver diseases.

  8. blocking tumor-driven inflammation by ATX inhibition is effective in decreasing tumor growth in breast cancers where the cancer cells express negligible ATX.

  9. Autotaxin is transported in the aortic valve by lipoprotein(a) and is also secreted by valve interstitial cells.

  10. Data suggest a role for the autotaxin-lysophosphatidic acid axis in toluene diisocyanate toxicity.

Mouse (Murine) Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) interaction partners

  1. inducible, ubiquitous genetic deletion of ATX in adult mice, as well as long-term potent pharmacologic inhibition, are well tolerated, alleviating potential toxicity concerns of ATX therapeutic targeting.

  2. findings indicate that the ATX level must be carefully regulated to ensure coordinated vascular formation

  3. Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer

  4. These findings identify ATX and LPA2 (show LPAR2 Antibodies) as radiation-regulated genes that appear to play a physiological role in DNA repair.

  5. The results are discussed in terms of ATX regulation in wound healing and cancer.We, therefore, demonstrate the concept that accumulation of LPA in the circulation decreases ATX production

  6. blocking tumor-driven inflammation by ATX inhibition is effective in decreasing tumor growth in breast cancers where the cancer cells express negligible ATX.

  7. ATX expression and lysophosphatidic acid production are significantly enhanced in LPS (show TLR4 Antibodies) treated BV-2 cells.

  8. Enpp2(+/-) mice and adipocyte-specific Enpp2 knockout mice fed a high-fat diet showed smaller weight gains and less insulin (show INS Antibodies) resistance than control mice, as well as more functionally active brown adipose tissue and increased energy expenditure.

  9. high levels of c-Jun (show JUN Antibodies) enhance motility in part by driving the expression of ENPP2/Autotaxin

  10. Autotaxin generates lysophosphatidic acid from lysophophatidylcholine. The role of this pathway in T-lymphocyte homing, inflammation, and airway remodeling is studied and inhibitors are tested. Review.

Pig (Porcine) Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) interaction partners

  1. ENPP2 may play an important role in the establishment of pregnancy in pigs by regulating lysophosphatidic acid production at the maternal-conceptus interface.

Cow (Bovine) Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) interaction partners

  1. These results indicate that the generation of cyclic phosphatidic acid and lysophosphatidic acid in serum is mainly attributed to autotaxin.

ENPP2 Antigen Profile

Protein Summary

The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with ENPP2

  • ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2) antibody
  • ectonucleotide pyrophosphatase/phosphodiesterase 2 (enpp2) antibody
  • ectonucleotide pyrophosphatase/phosphodiesterase 2 (Enpp2) antibody
  • ATX antibody
  • ATX-X antibody
  • AUTOTAXIN antibody
  • LysoPLD antibody
  • MGC132047 antibody
  • NPP2 antibody
  • Npps2 antibody
  • PD-Ialpha antibody
  • Pdnp2 antibody
  • zgc:63550 antibody

Protein level used designations for ENPP2

autotaxin , ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) , ectonucleotide pyrophosphatase/phosphodiesterase 2 , ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform 2 preproprotein , ectonucleotide pyrophosphatase/phosphodiesterase family member 2 , E-NPP 2 , autotaxin-t , extracellular lysophospholipase D , phosphodiesterase I/nucleotide pyrophosphatase 2 , plasma lysophospholipase D , lysoPLD , phosphodiesterase I/nucleotide pyrophosphatase 2 (autotaxin) , atx

GENE ID SPECIES
100057101 Equus caballus
464353 Pan troglodytes
548690 Xenopus (Silurana) tropicalis
705287 Macaca mulatta
735240 Xenopus laevis
100173553 Pongo abelii
100219257 Taeniopygia guttata
5168 Homo sapiens
18606 Mus musculus
84050 Rattus norvegicus
393575 Danio rerio
420361 Gallus gallus
482026 Canis lupus familiaris
503658 Sus scrofa
532663 Bos taurus
Selected quality suppliers for anti-ENPP2 (ENPP2) Antibodies
Did you look for something else?