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Egl Nine Homolog 1 (C. Elegans) (EGLN1) ELISA Kits

The protein encoded by EGLN1 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Additionally we are shipping Egl Nine Homolog 1 (C. Elegans) Antibodies (148) and Egl Nine Homolog 1 (C. Elegans) Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EGLN1 112405 Q91YE3
Anti-Rat EGLN1 EGLN1 308913  
EGLN1 54583 Q9GZT9
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Top Egl Nine Homolog 1 (C. Elegans) ELISA Kits at antibodies-online.com

Showing 2 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 13.2 pg/mL 31.25-2000 pg/mL 96 Tests Log in to see 9 to 11 Days
$810.53
Details
Mouse 0.108 ng/mL 0.31-20 ng/mL   96 Tests Log in to see 9 to 11 Days
$833.68
Details

More ELISA Kits for Egl Nine Homolog 1 (C. Elegans) Interaction Partners

Xenopus laevis Egl Nine Homolog 1 (C. Elegans) (EGLN1) interaction partners

  1. comparative analysis of phd1 (show EGLN2 ELISA Kits), 2, and 3 expression in Xenopus laevis

Mouse (Murine) Egl Nine Homolog 1 (C. Elegans) (EGLN1) interaction partners

  1. Stabilized HIF-1alpha (show HIF1A ELISA Kits) induced by PHD2 conditional knockout resulted in the transition of muscle fibers toward a slow fiber type via a calcineurin (show PPP3CA ELISA Kits)/NFATc1 (show NFATC1 ELISA Kits) signaling pathway.

  2. HIF-P4H-2 inhibition may be a novel strategy for protecting against the development of atherosclerosis.

  3. findings show hypoxia and loss of PHD2 revert cancer-associated fibroblast (CAF (show LAMA2 ELISA Kits)) activation; this reversion is associated with loss of matrix stiffening and consequently reduction in spontaneous metastases to lungs and liver

  4. Data (including data from studies in transgenic/knockout mice) suggest that expression of Phd2/Egln1 in chondrocytes plays key role in chondrogenesis, osteogenesis, and developmental gene expression regulation.

  5. a genetic link between EGLN1 and VWF (show VWF ELISA Kits) in a constitution specific manner which could modulate thrombosis/bleeding susceptibility and outcomes of hypoxia, is reported.

  6. PHD2 in the liver has a role in survival in lactic acidosis by activating the Cori cycle

  7. Regulatory link was discovered between mitochondrial Txnrd and the JNK (show MAPK8 ELISA Kits)-PHD2-Hif-1alpha (show HIF1A ELISA Kits) axis, which highlights how the loss of Txnrd2 (show TXNRD2 ELISA Kits) and the resulting altered mitochondrial redox balance impairs tumor growth as well as tumor-related angiogenesis.

  8. combined deletion of Phd2 and Phd3 (show EGLN3 ELISA Kits) dramatically decreased expression of phospholamban (PLN (show PLN ELISA Kits)), resulted in sustained activation of calcium/calmodulin-activated kinase II (CaMKII (show CAMK2G ELISA Kits)), and sensitized mice to chronic beta-adrenergic stress-induced myocardial injury

  9. PHD2 activity is a critical contributor to the high fat-diet-induced cardiac dysfunction.

  10. Phd2 plays an important role in regulating bone formation in part by modulating expression of Osx (show SP7 ELISA Kits) and bone formation marker genes.

Human Egl Nine Homolog 1 (C. Elegans) (EGLN1) interaction partners

  1. The present study demonstrated that the antiapoptotic effect of TMP in CoCl2-induced HUVECs was, at least in part, via the regulation of the PHD2/HIF-1alpha (show HIF1A ELISA Kits) signaling pathway.

  2. the levels of both miR-182 and HIF1alpha were elevated, while the expression PHD2 and FIH1 was downregulated in a mouse model of prostate cancer.

  3. findings show hypoxia and loss of PHD2 revert cancer-associated fibroblast (CAF (show KAT2B ELISA Kits)) activation

  4. In this article, UTMD/PEI mediated gene transfection was investigated and the US parameters were optimized. Furthermore, the biological effects of PHD2 shRNA were investigated in H9C2 cells.

  5. a genetic link between EGLN1 and VWF (show VWF ELISA Kits) in a constitution specific manner which could modulate thrombosis/bleeding susceptibility and outcomes of hypoxia, is reported.

  6. Data show that dimethyl-2-ketoglutarate (DKG) inhibits hypoxia-inducible factor 1alpha (HIF-1alpha (show HIF1A ELISA Kits)) proline hydroxylation and degradation mediated by prolyl-4-hydroxylase PHD2.

  7. The kinetic properties of PHD2 and FIH (show CASR ELISA Kits) with respect to oxygen reflect their cellular hypoxia-sensing ability.

  8. Germ-line PHD1 (show EGLN2 ELISA Kits) and PHD2 mutations detected in patients with pheochromocytoma/paraganglioma-polycythemia

  9. The association between EGLN1 and HIF-1AN single nucleotide polymorphisms and acute mountain sickness in a Han Chinese population, was examined.

  10. Compared to those with high PHD2 expressions, patients with low PHD2 expression had significantly longer DFS (show FST ELISA Kits) and OS periods.

Egl Nine Homolog 1 (C. Elegans) (EGLN1) Antigen Profile

Antigen Summary

The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).

Gene names and symbols associated with EGLN1

  • egl nine homolog 1 (C. elegans) (EGLN1) antibody
  • egl nine homolog 1 (egln1) antibody
  • egl nine homolog 1 (C. elegans) (egln1) antibody
  • EGL nine homolog 1 (C. elegans) (Egln1) antibody
  • egl-9 family hypoxia-inducible factor 1 (EGLN1) antibody
  • AI503754 antibody
  • C1orf12 antibody
  • ECYT3 antibody
  • EGLN1 antibody
  • egln2 antibody
  • Hif-p4h-2 antibody
  • HIF-PH2 antibody
  • HIFPH2 antibody
  • HPH-2 antibody
  • HPH2 antibody
  • ORF13 antibody
  • PHD-2 antibody
  • PHD2 antibody
  • SM-20 antibody
  • SM20 antibody
  • zgc:92314 antibody
  • ZMYND6 antibody

Protein level used designations for EGLN1

egl nine homolog 1 (C. elegans) , egl nine homolog 1 , egl nine homolog 1-like , egl nine homolog 2 , Hif-p4h-2 , HIF-prolyl hydroxylase 2 , hypoxia-inducible factor prolyl hydroxylase 2 , prolyl hydroxylase domain-containing protein 2 , HIF prolyl hydroxylase 2 , egl nine-like protein 1 , zinc finger MYND domain-containing protein 6

GENE ID SPECIES
421528 Gallus gallus
469708 Pan troglodytes
534075 Bos taurus
100153461 Sus scrofa
100454843 Pongo abelii
100594374 Nomascus leucogenys
446395 Xenopus laevis
436868 Danio rerio
488971 Canis lupus familiaris
112405 Mus musculus
308913 Rattus norvegicus
54583 Homo sapiens
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