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Egl Nine Homolog 2 (C. Elegans) (EGLN2) ELISA Kits

The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. Additionally we are shipping Egl Nine Homolog 2 (C. Elegans) Antibodies (124) and Egl Nine Homolog 2 (C. Elegans) Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse EGLN2 EGLN2 112406 Q91YE2
Anti-Rat EGLN2 EGLN2 308457 Q6AYU4
Anti-Human EGLN2 EGLN2 112398 Q96KS0
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More ELISA Kits for Egl Nine Homolog 2 (C. Elegans) Interaction Partners

Xenopus laevis Egl Nine Homolog 2 (C. Elegans) (EGLN2) interaction partners

  1. comparative analysis of phd1, 2, and 3 expression in Xenopus laevis

Mouse (Murine) Egl Nine Homolog 2 (C. Elegans) (EGLN2) interaction partners

  1. PHD1 and PHD3 (show EGLN3 ELISA Kits) deletions promote angiogenesis in ischemia-injured tissue by increasing HIF1-alpha (show HIF1A ELISA Kits) stability.

  2. Rosiglitazone increases PHD (show PDC ELISA Kits) expression in a PPARgamma (show PPARG ELISA Kits)-dependent manner and that this leads to the commitment of anti-adipogenic proteins to the ubiquitination-proteasomal pathway and to the subsequent induction of adipocyte differentiation.

  3. PHD-1 deficient mouse appears to be the first animal model showing neuroepithelial bodies cell hyperplasia

  4. Alterations in the function of all 3 isoforms of prolyl-4-hydroxylase enzymes (PHD1-3) in the first 24 h following transient focal cerebral ischaemia are reported.

  5. Data show it is feasible to reactivate hepatic erythropoietin (show EPO ELISA Kits) production using systemically delivered siRNAs targeting the EglN1 (show EGLN1 ELISA Kits), EglN2 and EglN3 (show EGLN3 ELISA Kits) prolyl hydroxylase mRNA specifically in the liver.

  6. silencing of PHD-1 attenuates myocardial ischemia/reperfusion injury probably by enhancing HIF-1alpha (show HIF1A ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits)/endothelial nitric oxide synthase (show NOS3 ELISA Kits)/nuclear factor-kappaB and Bcl-2 (show BCL2 ELISA Kits) signaling pathway

  7. role for PHD1 as a positive regulator of intestinal epithelial cell apoptosis in the inflamed colon

  8. Prolyl hydroxylase enzyme (PHD (show PDC ELISA Kits)) is the key enzyme responsible for degrading HIF-1 (show HIF1A ELISA Kits). HIF activation is an approach to increase vascularity and bone formation following skeletal trauma.

  9. Loss of PHD1 provided tolerance of hepatocytes to acute hypoxia and protected them against ischemia/reperfusion damage.

  10. Egln1 (show EGLN1 ELISA Kits)/2/3 play dual roles in chondrocyte growth, acting as oxygen sensors and mediators of late stage events in the cell cycle.

Human Egl Nine Homolog 2 (C. Elegans) (EGLN2) interaction partners

  1. PHD1 is phosphorylated by CDK2 (show CDK2 ELISA Kits), CDK4 (show CDK4 ELISA Kits) and CDK6 (show CDK6 ELISA Kits) at Serine 130.

  2. siRNA-mediated knockdown of PHD1 inhibited glucose-stimulated insulin (show INS ELISA Kits) secretion in pancreatic Beta cells.

  3. EglN2 associates with the NRF1 (show NFE2L1 ELISA Kits)-PGC1alpha complex and controls mitochondrial function in breast cancer

  4. rs3733829 in the EGLN2 gene is significantly associated with the risk of COPD (show ARCN1 ELISA Kits) in Chinese populations of Hainan province.

  5. Germ-line PHD1 and PHD2 (show EGLN1 ELISA Kits) mutations detected in patients with pheochromocytoma/paraganglioma-polycythemia

  6. study conducted to investigate the association between gastric cancer (GC) susceptibility with a 4-bp insertion/deletion polymorphism (rs10680577) in the proximal promoter of EGLN2; findings showed that the heterozygote and the homozygote 4-bp del/del confer a significantly increased risk of GC

  7. Data indicate that the prolyl hydrolase 1 (PHD1) rs10680577 polymorphism is associated with the risk of non-small cell lung cancer in a Chinese population.

  8. PHD-1 played an important role in hypoxic response pathway of trophoblast through modulating the level of HIF-2alpha (show EPAS1 ELISA Kits).

  9. PHD1 could induce cell cycle arrest in lung cancer cells, resulting in the suppression of cell proliferation.

  10. Results show that variants in two adjacent genes, EGLN2 and CYP2A6 (show CYP2A6 ELISA Kits), influence smoking behavior related to disease risk.

Egl Nine Homolog 2 (C. Elegans) (EGLN2) Antigen Profile

Antigen Summary

The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.

Gene names and symbols associated with EGLN2

  • egl nine homolog 1 (egln1) antibody
  • egl nine homolog 2 (C. elegans) (EGLN2) antibody
  • Egl nine homolog 2 (egln2) antibody
  • egl nine homolog 2 (egln2) antibody
  • EGL nine homolog 2 (C. elegans) (Egln2) antibody
  • egl-9 family hypoxia-inducible factor 2 (EGLN2) antibody
  • 0610011A13Rik antibody
  • C85656 antibody
  • egln2 antibody
  • EIT6 antibody
  • Hif-p4h-1 antibody
  • HIF-PH1 antibody
  • HIFPH1 antibody
  • HPH-1 antibody
  • HPH-3 antibody
  • Ier4 antibody
  • PHD-1 antibody
  • Phd1 antibody
  • phd2 antibody
  • SM-20 antibody

Protein level used designations for EGLN2

EGL nine homolog 2 , egl nine homolog 2 , Egl nine homolog 2 , EGL nine (C.elegans) homolog 2 , egl nine homolog 2 (C. elegans) , egl nine homolog 2-like , HIF-PH1 , HIF-prolyl hydroxylase 1 , HPH-1 , falkor , hypoxia-inducible factor prolyl hydroxylase 1 , immediate early response 4 , prolyl hydroxylase domain-containing protein 1 , HIF-1alpha prolyl-4-hydroxylase-1 , estrogen-induced tag 6

GENE ID SPECIES
548714 Xenopus (Silurana) tropicalis
100172704 Pongo abelii
100306807 Salmo salar
456049 Pan troglodytes
703083 Macaca mulatta
100523673 Sus scrofa
100584172 Nomascus leucogenys
100158265 Xenopus laevis
112406 Mus musculus
484495 Canis lupus familiaris
308457 Rattus norvegicus
536763 Bos taurus
112398 Homo sapiens
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