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anti-ElaC Homolog 2 (E. Coli) (ELAC2) Antibodies

The protein encoded by ELAC2 has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. Additionally we are shipping ElaC Homolog 2 (E. Coli) Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ELAC2 68626 Q80Y81
ELAC2 60528 Q9BQ52
ELAC2 282826 Q8CGS5
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Top anti-ElaC Homolog 2 (E. Coli) Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using ELAC2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Breast, Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IHC (p) Formalin-Fixed, Paraffin-Embedded Human Breast, Epithelium tissue stained with ELAC2 / HPC2 antibody at 10 µg/ml after heat-induced antigen retrieval. Formalin-Fixed, Paraffin-Embedded Human Spleen tissue stained with ELAC2 / HPC2 antibody at 10 µg/ml after heat-induced antigen retrieval. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated IP, WB ELAC2 MaxPab rabbit polyclonal antibody. Western Blot analysis of ELAC2 expression in human liver. Immunoprecipitation of ELAC2 transfected lysate using anti-ELAC2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with ELAC2 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated IF, ELISA Immunofluorescence of monoclonal antibody to ELAC2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

ELAC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against ElaC Homolog 2 (E. Coli) Interaction Partners

Human ElaC Homolog 2 (E. Coli) (ELAC2) interaction partners

  1. ELAC2 mutations cause a mitochondrial RNA processing defect associated with hypertrophic cardiomyopathy.

  2. results indicate that ELAC2 functions as a tRNase Z in human mitochondria and suggest that mt-tRNase Z preferentially cleaves molecules already processed by the proteinaceous mtRNase P

  3. ELAC2 and PTCD1 affect the 3' end processing of tRNAs.

  4. analysis of dual nuclear/mitochondrial targeting of the ELAC2 gene product by alternative translation initiation

  5. Data describe polymorphisms in the HPC/ELAC-2 and alpha 1-antitrypsin (show SERPINA1 Antibodies) genes that correlate with human diseases in an Indian population.

  6. ELAC2 polymorphisms are associated with prostate cancer.

  7. Our findings corroborate the involvement of ELAC2, MSR1 (show MSR1 Antibodies), and RNASEL (show RNASEL Antibodies) in the etiology of prostate cancer even in individuals without a family history.

  8. variation in the putative prostate cancer susceptibility gene ELAC2 contributes to the elevated risk of prostate cancer in Afro-Caribbean males from Tobago

  9. Meta-analysis of associations of the Ser217Leu and Ala541Thr variants in ELAC2 (HPC2) and prostate cancer

  10. Although the Leu217 and Thr541 variants of ELAC2 are less common in Japanese than in Caucasians, both variants confer significantly increased risk of prostate cancer in Japanese.

ElaC Homolog 2 (E. Coli) (ELAC2) Antigen Profile

Protein Summary

The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ELAC2

  • elaC homolog 2 (E. coli) (ELAC2) antibody
  • elaC homolog 2 (E. coli) (Elac2) antibody
  • elaC ribonuclease Z 2 (ELAC2) antibody
  • elaC ribonuclease Z 2 (Elac2) antibody
  • 1110017O07Rik antibody
  • D11Wsu80e antibody
  • ELC2 antibody
  • HPC2 antibody

Protein level used designations for ELAC2

RNase Z 2 , elaC homolog protein 2 , ribonuclease Z 2 , tRNA 3 endonuclease 2 , tRNase Z 2 , tRNase Z(L) , zinc phosphodiesterase ELAC protein 2 , elaC homolog 2 , heredity prostate cancer protein 2 , putative prostate cancer susceptibility protein HPC2/ELAC2 , tRNase Z (long form)

GENE ID SPECIES
489511 Canis lupus familiaris
68626 Mus musculus
450109 Pan troglodytes
60528 Homo sapiens
282826 Rattus norvegicus
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