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May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Additionally we are shipping EMILIN2 Kits (12) and EMILIN2 Antibodies (6) and many more products for this protein.
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Data suggested mechanisms for homo- and hetero-typic EMILINs multimers formation: EMILIN1 (show EMILIN1 Proteins) or EMILIN2 alone can form trimers and multimers in the absence of each other or they can co-polymerize in a head-to-tail fashion to form hetero-typic multimers.
Identify emilin2 as a key extracellular regulator of the Wnt (show WNT2 Proteins) signalling pathway suppressing breast cancer cell growth and migration.
Apoptosis plays a fundamental role in maintaining epidermal homeostasis, balancing keratinocytes proliferation, and forming the stratum corneum. EMILIN2 is known to trigger the apoptosis of different cell lines
The possibility of using EMILIN2 fragments as potent antineoplastic tools for cancer treatment.
Results suggest that the expression of EMILIN2 triggers the apoptosis of different cell lines by activation of death receptors.
EMILIN1 (show EMILIN1 Proteins) interacts with anthrax protective antigen and inhibits toxin action in vitro. EMILIN1 (show EMILIN1 Proteins) may be a potential target and/or a protein useful for countermeasures against B. anthracis toxin lethality.
EMILIN1 (show EMILIN1 Proteins) may attenuate the effects of EMILIN2 on platelet aggregation and thrombosis.
cochlear emilin-2 mRNA is expressed in the tympanic border cells and an antibody detected protein in the extracellular matrix surrounding the collagenous fibers in the cochlear basilar membrane
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity. Major component of the cochlear basilar membrane (BM) which may contribute to the developmental assembly or function of the BM.
elastin microfibril interfacer 2
, elastin microfibril interface-located protein 2
, extracellular glycoprotein EMILIN-2
, elastin microfibril interface located protein 2