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Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.. Additionally we are shipping Elongation Factor RNA Polymerase II Antibodies (91) and Elongation Factor RNA Polymerase II Proteins (3) and many more products for this protein.
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ELL (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 (show THBS1 ELISA Kits) regulation
This work reveals a previously unrecognized function for ELL as an E3 ubiquitin ligase for c-Myc (show MYC ELISA Kits) and a potential tumour suppressor.
The Tax (show CNTN2 ELISA Kits) oncogene (show RAB1A ELISA Kits) enhances ELL incorporation into p300 (show EP300 ELISA Kits) and P-TEFb (show CCNT1 ELISA Kits) containing protein complexes to activate transcription.
eleven-nineteen lysine-rich leukemia protein enhanced E2F1 (show E2F1 ELISA Kits) deacetylation via recruitment of histone deacetylase 1 (show HDAC1 ELISA Kits)
ELL is an essential player for RNA Pol II restart during cellular DNA damage response.
Studies indicate that the super elongation complex (SEC) consisting of ELL, P-TEFb (CDK9) and MLL required for rapid transcriptional induction in the presence or absence of paused RNA polymerase II (Pol II).
ELL has an early and essential role during rapid high-amplitude gene expression that is required for both Pol II pause site entry and release
Our findings suggest that ELL and HIF-1alpha (show HIF1A ELISA Kits) are binding partners and can modulate the functions of each other in hypoxia.
In the Acute Myeloid Leukemia (show BCL11A ELISA Kits) patients, detected MLL (show MLL ELISA Kits) rearrangements consisting of MLL (show MLL ELISA Kits)/AF6 (show MLLT4 ELISA Kits), MLL (show MLL ELISA Kits)/AF9 (show MLLT3 ELISA Kits), MLL (show MLL ELISA Kits)/AF17 , MLL (show MLL ELISA Kits)/ELL and MLL (show MLL ELISA Kits) partial tandem duplication. MLL (show MLL ELISA Kits) rearrangement include chromosome translocation and partial tandem duplication.
Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.
RNA polymerase II elongation factor ELL
, ELL gene (11-19 lysine-rich leukemia gene)
, eleven-nineteen lysine-rich leukemia protein
, protein phosphatase 1, regulatory subunit 68
, RNA POLYMERASE II ELONGATION FACTOR ELL (ELEVEN-NINETEEN LYSINE-RICH LEUKEMIA PROTEIN)