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Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation (By similarity). Additionally we are shipping Elongator Acetyltransferase Complex Subunit 2 Antibodies (22) and many more products for this protein.
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ELP2 mutation is implicated in severe intellectual disability, spastic diplegia, and self-injurious behavior described in two brothers.
Studied the possible relationship between STATIP1, STAT3 and CML resistance.
Elp2 and STAT-3 (show STAT3 Proteins) mediate, at least in part, the stimulation of Hsp70 (show HSP70 Proteins) expression by 4PBA.
Targeting ELP2 activity as a novel therapeutic option to limit the inhibition of osteoblast differentiation by inflammatory microenvironment.
US28 induces proliferation in HCMV-infected tumors by establishing a positive feedback loop through activation of the IL-6 (show IL6 Proteins)-STAT3 (show STAT3 Proteins) signaling axis.
STAT3 (show STAT3 Proteins) interacts with STRA13 (show STRA13 Proteins) and modulates transcription of STAT3 (show STAT3 Proteins)-dependent targets.
Data show that HMGA1a (show HMGA1 Proteins) binding activity in nuclear fractions from murine retina, but not from hippocampus, resulted in STAT3 interacting protein 1 (StIP1) that formed a novel complex with HMGA1a (show HMGA1 Proteins), STAT3 (show STAT3 Proteins) and homeodomain-interacting protein kinase 2 (HIPK2 (show HIPK2 Proteins)).
ELP2 positively contributes to resistance to the necrotrophic fungal pathogens Botrytis cinerea and Alternaria brassicicola.
The elp2 mutant had accelerated differentiation of root stem cells and cell division was more active in its quiescent centre (QC); the key transcription factors responsible for maintaining root stem cell and QC identity were all strongly down-regulated.
ELP2 plays an evolutionarily conserved role in DNA demethylation/methylation in plants and likely functions as an epigenetic regulator of plant immune responses.
AtELP2 is an accelerator of defense gene induction, which functions largely independently of NPR1 in establishing plant immunity.
Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation (By similarity). Promotes organs development by modulating cell division rate. Prevents abscisic acid (ABA) signaling leading to stomatal closure and seedling growth inhibition. Involved in oxidative stress signaling. Prevents anthocyanins accumulation. Accelerator of defense gene induction required for rapid defense gene induction, and for the establishment of both basal and effector-triggered immunity (ETI), in a NPR1-independent manner, but is not required for systemic acquired resistance (SAR) establishment.
elongator complex protein 2
, STAT3-interacting protein 1
, elongation protein 2 homolog
, elongator protein 2
, signal transducer and activator of transcription 3 interacting protein 1
, signal transducer and activator of transcription interacting protein 1