anti-Embryonic Ectoderm Development (EED) Antibodies

EED encodes a member of the Polycomb-group (PcG) family. Additionally we are shipping Embryonic Ectoderm Development Kits (24) and Embryonic Ectoderm Development Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EED 8726 O75530
EED 13626 Q921E6
EED 293104  
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Top anti-Embryonic Ectoderm Development Antibodies at antibodies-online.com

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IF, WB <b>WB Suggested Anti-EED Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:2500<br><b>Positive Control: </b>OVCAR-3 cell lysate WB Suggested Anti-EED <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.500 <br /> Positive Control: OVCAR-3 cell lysate <br /> EED is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-EED Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate Host: Rabbit <br /> Target Name: EED <br /> Sample Tissue: HepG2Lane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide <br />Primary Antibody Concentration: 4.0 µg/mL Peptide Concentration:..0 µg/mL Lysate Quantity:.41 µg/laneGel Concentration: 12 % 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged EED is 0.1 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Western Blot: EED Antibody [NBP1-33417] - Sample (30 ug of whole cell lysate) A: A431 B: H1299 10% SDS PAGE; antibody diluted at 1:1000. Immunohistochemistry-Paraffin: EED Antibody [NBP1-33417] - Paraffin-embedded SAS Xenograft, using antibody at 1:100 dilution. 0.1 mL Log in to see 7 to 9 Days
$447.56
Details

EED Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Embryonic Ectoderm Development Antibodies

  1. Cow (Bovine) Polyclonal EED Primary Antibody for IF, WB - ABIN2776407 : Rakotobe, Violot, Hong, Gouet, Boulanger: Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed beta-propeller domain of the HIV-1 cellular interactor EED. in Virology journal 2008 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal EED Primary Antibody for ELISA, WB - ABIN522175 : Martin, Popov, Aguilo, OLoghlen, Raguz, Snijders, Dharmalingam, Li, Thymiakou, Carroll, Zeisig, So, Peters, Episkopou, Walsh, Gil: Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK?a regulation. in The EMBO journal 2013 (PubMed)

More Antibodies against Embryonic Ectoderm Development Interaction Partners

Human Embryonic Ectoderm Development (EED) interaction partners

  1. These findings support that Weaver (show KCNJ6 Antibodies) syndrome is a disorder with locus heterogeneity and can be due to pathogenic variants in either EZH2 (show EZH2 Antibodies) or EED. This case highlights the utility of exome sequencing as a clinical diagnostic tool for novel gene discovery as well as the importance of re-examination of exome data as new information about gene-disease associations becomes available.

  2. we have found two unrelated families of different ethnicities, with a similar rare phenotype, both associated with de novo mutations in this member of the PRC2 complex, we are confident that EED is indeed a novel overgrowth gene.

  3. Mutations of SUZ12 (show SUZ12 Antibodies) and EED are reported to have tumor suppressive functions. (Review)

  4. These results suggest that the SNPs of the EED gene might not be associated with susceptibility to CRC (show CALR Antibodies).

  5. An integral role for EED as an epigenetic exchange factor coordinating the activities of PRC1 (show PRC1 Antibodies) and 2, is reported.

  6. Data show that overall enhancer of zeste 2 (EZH2 (show EZH2 Antibodies)), embryonic ectoderm development (EED) and suppressor of zeste 12 homolog (SUZ12 (show SUZ12 Antibodies)) expression in the colorectal cancer (CRC (show CALR Antibodies)) tissues was significantly increased than in the non-cancerous tissue.

  7. EED, a component of Polycomb (show CBX2 Antibodies) repressive complex-2 (PRC2) that catalyzes methylation of lysine 27 of histone H3 (show HIST3H3 Antibodies) (H3K27), was involved in epithelial-mesenchymal transition (EMT (show ITK Antibodies)) of cancer cells induced by Transforming Growth Factor-beta (TGF-beta).

  8. Polycomb (show CBX2 Antibodies) repressive complex 2 is recurrently inactivated through EED or SUZ12 (show SUZ12 Antibodies) loss in malignant peripheral nerve sheath tumors.

  9. EZH2 (show EZH2 Antibodies)-EED is necessary and sufficient for binding to the lncRNA HOTAIR.

  10. Although inactivating mutations in PRC2-encoding genes EZH2 (show EZH2 Antibodies), EED, and SUZ12 (show SUZ12 Antibodies) are present in T-cell acute lymphoblastic leukemia and in myeloid malignancies, gain-of-function mutations in EZH2 (show EZH2 Antibodies) are frequently observed in B-cell lymphoma.

Mouse (Murine) Embryonic Ectoderm Development (EED) interaction partners

  1. Deletion of Eed but not Ezh2 (show EZH2 Antibodies) from embryonic urothelial progenitors caused premature differentiation of Krt5 (show KRT5 Antibodies)+ basal cells and ectopic expression of squamous cell markers.

  2. in the skin epithelium, EED, Suz12 (show SUZ12 Antibodies), and Ezh1 (show EZH1 Antibodies)/2 function largely as subunits of the PRC2 complex and have roles in skin development

  3. EED is required for proper erythropoiesis and for formation of hematopoietic progenitor and stem cells, but is dispensable for endothelial lineage commitment and early vascular patterning

  4. Genetic inactivation of Ezh2 (show EZH2 Antibodies) or Eed cooperates with NRASQ61K in leukemogenesis.

  5. EED affects the lymphoid versus myeloid decision processes within the lymphomyeloid lineage

  6. Inactivation of Eed impedes MLL (show MLL Antibodies)-AF9 (show MLLT3 Antibodies)-mediated leukemogenesis through Cdkn2a (show CDKN2A Antibodies)-dependent and Cdkn2a (show CDKN2A Antibodies)-independent mechanisms in a murine model.

  7. Data suggest that Eed (embryonic ectoderm development) is necessary to silence the pluripotency network during differentiation.

  8. An integral role for EED as an epigenetic exchange factor coordinating the activities of PRC1 (show PRC1 Antibodies) and 2, is reported.

  9. a microRNA encoded by the imprinted Dlk1 (show DLK1 Antibodies)-Dio3 (show DIO3 Antibodies) region of mouse chromosome 12, miR (show MLXIP Antibodies)-323-3p, targets Eed (embryonic ectoderm development) mRNA.

  10. Ectopic gain of EED along with depletion of KDM6B (show Kdm6b Antibodies) in preimplantation mouse embryos abrogates CDX2 (show CDX2 Antibodies) and GATA3 (show GATA3 Antibodies) gene expression in the nascent trophoectoderm lineage.

Embryonic Ectoderm Development (EED) Antigen Profile

Protein Summary

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with EED

  • embryonic ectoderm development (eed) antibody
  • embryonic ectoderm development (EED) antibody
  • embryonic ectoderm development (eed-b) antibody
  • embryonic ectoderm development (Eed) antibody
  • embryonic ectoderm development (LOC100344036) antibody
  • embryonic ectoderm development (eed-a) antibody
  • eed antibody
  • ENSMUSG00000039373 antibody
  • HEED antibody
  • l(7)5Rn antibody
  • l7Rn5 antibody
  • lusk antibody
  • psXEED antibody
  • WAIT1 antibody
  • Xeed antibody
  • Xeed-A antibody
  • Xeed-B antibody
  • zgc:112509 antibody

Protein level used designations for EED

polycomb protein eed , embryonic ectoderm development , WD protein associating with integrin cytoplasmic tails 1 , polycomb protein EED , embryonic ectoderm development protein variant 1 , polycomb protein eed-B , embryonic ectoderm development protein , lethal, Chr 7, Rinchik 5 , polycomb protein eed-A

GENE ID SPECIES
550079 Xenopus (Silurana) tropicalis
703866 Macaca mulatta
100601094 Nomascus leucogenys
8726 Homo sapiens
550463 Danio rerio
398420 Xenopus laevis
426381 Gallus gallus
404183 Bos taurus
13626 Mus musculus
293104 Rattus norvegicus
100344036 Oryctolagus cuniculus
100728793 Cavia porcellus
476779 Canis lupus familiaris
101113712 Ovis aries
734571 Xenopus laevis
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