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Endoglin Proteins (ENG)

ENG encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. Additionally we are shipping Endoglin Antibodies (636) and Endoglin Kits (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ENG 2022 P17813
ENG 13805 Q63961
ENG 497010  
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Top Endoglin Proteins at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$547.80
Details
HOST_Human Cells Human His tag 50 μg Log in to see 16 Days
$382.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag,TRX tag   50 μg Log in to see 5 Days
$385.00
Details
HOST_Escherichia coli (E. coli) Human TRX tag,His tag   10 μg Log in to see 11 Days
$225.00
Details

ENG Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, , , , ,
Mouse (Murine) , , ,
,
Rat (Rattus)

Top referenced Endoglin Proteins

  1. Human ENG Protein expressed in Human Cells - ABIN2002178 : Cheifetz, Bellón, Calés, Vera, Bernabeu, Massagué, Letarte: Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells. in The Journal of biological chemistry 1992 (PubMed)
    Show all 4 references for ABIN2002178

  2. Human ENG Protein expressed in Human Cells - ABIN2002180 : Barbara, Wrana, Letarte: Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for ABIN2002180

  3. Mouse (Murine) ENG Protein expressed in Human Cells - ABIN2007757 : Koleva, Conley, Romero, Riley, Marto, Lux, Vary: Endoglin structure and function: Determinants of endoglin phosphorylation by transforming growth factor-beta receptors. in The Journal of biological chemistry 2006 (PubMed)
    Show all 4 references for ABIN2007757

  4. Human ENG Protein expressed in Wheat germ - ABIN1352793 : Banerjee, Dhara, Bacanamwo: Endoglin is a novel endothelial cell specification gene. in Stem cell research 2011 (PubMed)

More Proteins for Endoglin (ENG) Interaction Partners

Human Endoglin (ENG) interaction partners

  1. the TGFbeta1 (show TGFB1 Proteins) coreceptor Eng selectively regulates expression of multiple transient receptor potential channels in the setting of left or right ventricular pressure overload

  2. Increased ENG gene expression is associated with the Risk of Hepatocellular Carcinoma.

  3. Study of four patients with pulmonary arterial hypertension associated with human immunodeficiency virus infection found predisposing mutations in the BMPR2 (show BMPR2 Proteins), ACVRL1 (show ACVRL1 Proteins) and ENG genes.

  4. These results suggest that KLF6 (show KLF6 Proteins) regulates MMP14 (show MMP14 Proteins) transcription and is a critical player of the gene expression network triggered during endothelial repair.

  5. In placenta, higher Eng immunoexpression was observed in both villi types of the preeclamptic compared to normotensive groups. Irrespective of pregnancy type (normotensive versus preeclampsia), there was no significant effect of HIV status on Eng immunoexpression within the exchange and conducting villi

  6. Report marginal prognostic significance of endoglin expression in pancreatic ductal adenocarcinoma.

  7. CD105 acts as one of the receptors of TGF-beta1 (show TGFB1 Proteins) on vascular endothelial cells and induces the angiogenic pathway in oral squamous cell carcinoma.

  8. Endoglin-induced peritoneal mesothelial cell senescence may contribute to peritoneal dissemination of gastric cancer cells

  9. These results suggest a critical role for endoglin in integrin-mediated adhesion of mural cells.

  10. The expression of DLL4 (show DLL4 Proteins) was positively correlated with CD105-labeled MVD (show MVD Proteins).

Mouse (Murine) Endoglin (ENG) interaction partners

  1. the TGFbeta1 (show TGFB1 Proteins) coreceptor Eng selectively regulates expression of multiple transient receptor potential channels in the setting of left or right ventricular pressure overload

  2. Endothelial cell-specific endoglin expression in islets of Langerhans is sensitive to VEGF and plays partial roles in driving islet vascular development, however such regulation appears to be distinct to mechanisms required to modulate islet viability and size.

  3. Study provides evidence that the expression of endoglin is required for the establishment of uterine receptivity and the decidualization process, which mediate embryo adhesion or the attachment reaction.

  4. The changes in CD90 (show THY1 Proteins) and CD105 expression in the testis and ovary of mice are reported.

  5. the altered immune activity of endoglin deficient macrophages could help to explain the higher rate of infectious diseases seen in HHT1 patients.

  6. These results demonstrate a requirement for endoglin in descendants of Pax3 (show PAX3 Proteins)-expressing vascular cell precursors.

  7. The similarities in Eng-/- and Mlc2a-/- embryos suggest that Eng-/- mice may suffer from a primary heart developmental defect and secondary defects in vessel patterning.

  8. results of our study provide evidence of endoglin as a valid target for cancer therapy and support further development of plasmid shRNA delivery, which have prolonged antitumor effect, especially in combined schedules

  9. ENG deficiency leads to EC hyperpermeability through constitutive activation of RhoA (show RHOA Proteins) and destabilization of endothelial barrier function.

  10. endoglin is not localized with cell adhesion molecules involved in atherosclerosis, suggesting it might not participate in leukocyte accumulation in aorta of apoE (show APOE Proteins)-deficient mice during atherogenesis

Endoglin (ENG) Protein Profile

Protein Summary

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Endoglin Proteins (ENG)

  • endoglin (ENG)
  • endoglin (LOC100226246)
  • endoglin (Eng)
  • AI528660 protein
  • AI662476 protein
  • CD105 protein
  • DKFZp469D0419 protein
  • END protein
  • ENG protein
  • HHT1 protein
  • MGC137842 protein
  • ORW1 protein
  • S-endoglin protein

Protein level used designations for Endoglin Proteins (ENG)

endoglin (Osler-Rendu-Weber syndrome 1) , endoglin , endoglin-like , CD105 antigen , cell surface MJ7/18 antigen , transmembrane glycoprotein

GENE ID SPECIES
609166 Canis lupus familiaris
615844 Bos taurus
741046 Pan troglodytes
771557 Gallus gallus
100173392 Pongo abelii
100226246 Taeniopygia guttata
100357448 Oryctolagus cuniculus
100387791 Callithrix jacchus
397096 Sus scrofa
2022 Homo sapiens
13805 Mus musculus
497010 Rattus norvegicus
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