Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) ELISA Kits

Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Additionally we are shipping Endoplasmic Reticulum Aminopeptidase 2 Antibodies (28) and Endoplasmic Reticulum Aminopeptidase 2 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ERAP2 64167 Q6P179
ERAP2 513572 A6QPT7
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Top Endoplasmic Reticulum Aminopeptidase 2 ELISA Kits at antibodies-online.com

Showing 2 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.115 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 15 to 17 Days
$908.41
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Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
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More ELISA Kits for Endoplasmic Reticulum Aminopeptidase 2 Interaction Partners

Human Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) interaction partners

  1. ERAP2 deficiency causes increased MHC class I free heavy chain expression and up-regulation of the unfolded protein response pathway in anklyosing spondylitis.

  2. ERAP-2 significantly influences the B*27:05-bound peptidome by destroying some ligands and decreasing the abundance of many more ligands with N-terminal basic residues, while increasing the abundance of nonamers. The former effects are best explained by direct ERAP-2 trimming. The effects on peptide length might be attributed to ERAP-2-induced activation of ERAP-1 (show ERAP1 ELISA Kits) trimming. These data support the notion of a peptide-media

  3. study reveals fine-mapped AID risk variants that act as eQTLs with ERAP2 in thymus

  4. there is a significant association of ERAP2 with psoriatic arthritis and HLA-B27 negative psoriatic arthritis, while ERAP1 association is restricted only to HLA-B27 positive disease

  5. Increased expression of ERAP2 in GC-responders before therapy warrants further investigation into their role as potential predictors for the response to GC, and in the inflammatory process of rheumatoid arthritis.

  6. ERAP2 is associated with ankylosing spondylitis in HLA-B27 positive and HLA-B27 negative patients.

  7. ERAP2 might be associated with CLNM in PTMC.

  8. ERAP2 variation does not have a significant effect on PBMC intracellular and cell surface HLA-class I (show MICA ELISA Kits) expression and heavy chain formation, markers of ER stress or inflammatory cytokine production.

  9. Studies indicate the critical role of M1 aminopeptidases ERAP1 (show ERAP1 ELISA Kits), ERAP2 and NPEPPS (show NPEPPS ELISA Kits) in immune-mediated diseases.

  10. The risk allele of the polymorphism near ERAP2 is strongly associated with birdshot chorioretinopathy.

Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Antigen Profile

Antigen Summary

Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP1 (MIM 606832) and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II (TPP2\; MIM 190470) (Tanioka et al., 2003

Gene names and symbols associated with ERAP2

  • endoplasmic reticulum aminopeptidase 2 (ERAP2) antibody
  • ERAP2 antibody
  • L-RAP antibody
  • LRAP antibody

Protein level used designations for ERAP2

endoplasmic reticulum aminopeptidase 2 , leukocyte-derived arginine aminopeptidase , endoplasmic reticulum aminopeptidase 2-like

GENE ID SPECIES
461959 Pan troglodytes
700118 Macaca mulatta
100402550 Callithrix jacchus
64167 Homo sapiens
488897 Canis lupus familiaris
513572 Bos taurus
100171433 Pongo abelii
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