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Endoplasmic Reticulum Lectin 1 Proteins (ERLEC1)

ERLEC1 encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. Additionally we are shipping Endoplasmic Reticulum Lectin 1 Antibodies (3) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ERLEC1 27248 Q96DZ1
ERLEC1 66753 Q8VEH8
ERLEC1    
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Top Endoplasmic Reticulum Lectin 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,274.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ERLEC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Xenopus tropicalis

More Proteins for Endoplasmic Reticulum Lectin 1 (ERLEC1) Interaction Partners

Human Endoplasmic Reticulum Lectin 1 (ERLEC1) interaction partners

  1. Data indicate that the interaction of OS-9 and XTP3-B with CD147(CG) was inhibited by mutations to conserved residues in their lectin domains.

  2. Lectin activity of XTP3-B is required for its interaction with the misfolded glycoprotein alpha1-antitrypsin variant.

  3. mannose trimming enables delivery of a substrate glycoprotein from EDEM1 (show EDEM1 Proteins) to late endoplsmic reticulum degredation steps through association with XTP3-B

  4. Findings shed light on how tolerance to multiple cellular stresses at a metastatic site can be evoked by an integrated mechanism involving CIM, ERLEC1, which can function to coordinate those responses in a manner that promotes metastatic cell survival.

  5. XTP3-B specifically binds to AT(NHK), which is a well-known substrate of ERAD, via a C-terminal MRH domain in a glycan-dependent manner.

  6. Erlectin functions in N-glycan recognition in the endoplasmic reticulum and may regulate glycoprotein traffic

  7. XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1 (show SYVN1 Proteins)-SEL1L (show SEL1L Proteins) ubiquitin ligase complex and BiP (show GDF10 Proteins)

Mouse (Murine) Endoplasmic Reticulum Lectin 1 (ERLEC1) interaction partners

  1. Erlectin functions in N-glycan recognition in the endoplasmic reticulum and may regulate glycoprotein traffic

Endoplasmic Reticulum Lectin 1 (ERLEC1) Protein Profile

Protein Summary

This gene encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21.

Gene names and symbols associated with ERLEC1

  • endoplasmic reticulum lectin 1 (ERLEC1)
  • endoplasmic reticulum lectin 1 (Erlec1)
  • 4933407N01Rik protein
  • C2orf30 protein
  • CIM protein
  • CL24936 protein
  • CL25084 protein
  • XTP3-B protein
  • XTP3TPB protein

Protein level used designations for ERLEC1

ER lectin , XTP3-transactivated gene B protein , XTP3-transactivated protein B , cancer invasion and metastasis-related , erlectin 1 , erlectin

GENE ID SPECIES
27248 Homo sapiens
66753 Mus musculus
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