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Can mediate aggregation most likely through a homophilic molecular interaction (By similarity).. Additionally we are shipping ESAM Proteins (29) and ESAM Kits (11) and many more products for this protein.
Showing 10 out of 116 products:
Mouse (Murine) Monoclonal ESAM Primary Antibody for FACS, IF - ABIN2658754
Mikkola: ESAM: adding to the hematopoietic toolbox. in Blood 2009
Show all 3 references for ABIN2658754
Mouse (Murine) Monoclonal ESAM Primary Antibody for FACS, CyTOF - ABIN2663689
Wegmann, Ebnet, Du Pasquier, Vestweber, Butz: Endothelial adhesion molecule ESAM binds directly to the multidomain adaptor MAGI-1 and recruits it to cell contacts. in Experimental cell research 2004
Show all 2 references for ABIN2663689
Mouse (Murine) Monoclonal ESAM Primary Antibody for BR, FACS - ABIN2661878
Nasdala, Wolburg-Buchholz, Wolburg, Kuhn, Ebnet, Brachtendorf, Samulowitz, Kuster, Engelhardt, Vestweber, Butz: A transmembrane tight junction protein selectively expressed on endothelial cells and platelets. in The Journal of biological chemistry 2002
Show all 2 references for ABIN2661878
Human Polyclonal ESAM Primary Antibody for FACS, IHC - ABIN4900162
Roesli, Mumprecht, Neri, Detmar: Identification of the surface-accessible, lineage-specific vascular proteome by two-dimensional peptide mapping. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008
ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias
Serum ESAM is higher in type 2 diabetes mellitus than in controls and parallels oxidative stress.
ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules.
Runx3 (show RUNX3 Antibodies) is required for cell identity, homeostasis and function of splenic Esam(high) dendritic cells.
ESAM levels clearly mirror the shift of hematopoietic stem cells (HSC (show FUT1 Antibodies)) between quiescence and activation, and the intensity of expression is prominent in comparison with other HSC (show FUT1 Antibodies)-related antigens.
ESAM inactivation can reduce susceptibility to atherosclerosis by inhibiting plaque neovascularization and macrophage infiltration into the atheroma.
findings support a model in which ESAM localizes to platelet contacts following platelet activation in order to limit thrombus growth and stability
ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth
The direct interaction between ESAM and MAGI-1 (show CNKSR3 Antibodies) was confirmed by pull-down experiments. The two proteins formed stable complexes in transfected CHO (show COL11A1 Antibodies) cells.
At endothelial tight junctions ESAM participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts.
ESAM marks hematopoietic stem cells in murine fetal liver and will facilitate studies of hematopoiesis throughout life.
Thus, ESAM may regulate albumin (show ALB Antibodies) extravasation at the glomeruli and play a role in the initiation of diabetic nephropathy.
Can mediate aggregation most likely through a homophilic molecular interaction (By similarity).
endothelial cell adhesion molecule
, endothelial cell-selective adhesion molecule
, endothelial cell-specific adhesion molecule
, HUEL (C4orf1)-interacting protein
, LP4791 protein