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Endothelial Cell Adhesion Molecule Proteins (ESAM)

Can mediate aggregation most likely through a homophilic molecular interaction (By similarity).. Additionally we are shipping ESAM Antibodies (110) and ESAM Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ESAM 300519 Q6AYD4
ESAM 90952 Q96AP7
ESAM 69524 Q925F2
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Top ESAM Proteins at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag   20 μg Log in to see 5 Days
$167.48
Details

ESAM Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus) ,
,
Human , , , , , , ,
, , , ,
Mouse (Murine) , ,
,

Top referenced ESAM Proteins

  1. Rat (Rattus) ESAM Protein expressed in Human Cells - ABIN2009359 : Hirata Ki, Ishida, Penta, Rezaee, Yang, Wohlgemuth, Quertermous: Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cells. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for ABIN2009359

  2. Mouse (Murine) ESAM Protein expressed in Human Cells - ABIN2008474 : Ishida, Kundu, Yang, Hirata, Ho, Quertermous: Targeted disruption of endothelial cell-selective adhesion molecule inhibits angiogenic processes in vitro and in vivo. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN2008474

  3. Human ESAM Protein expressed in Human Cells - ABIN2002286 : Wegmann, Petri, Khandoga, Moser, Khandoga, Volkery, Li, Nasdala, Brandau, Fässler, Butz, Krombach, Vestweber: ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability. in The Journal of experimental medicine 2006 (PubMed)
    Show all 5 references for ABIN2002286

  4. Human ESAM Protein expressed in HEK-293 Cells - ABIN2181048 : Zhang, Henzel: Signal peptide prediction based on analysis of experimentally verified cleavage sites. in Protein science : a publication of the Protein Society 2004 (PubMed)
    Show all 2 references for ABIN2181048

More Proteins for Endothelial Cell Adhesion Molecule (ESAM) Interaction Partners

Human Endothelial Cell Adhesion Molecule (ESAM) interaction partners

  1. ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias

  2. Serum ESAM is higher in type 2 diabetes mellitus than in controls and parallels oxidative stress.

  3. ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules.

Mouse (Murine) Endothelial Cell Adhesion Molecule (ESAM) interaction partners

  1. Runx3 (show RUNX3 Proteins) is required for cell identity, homeostasis and function of splenic Esam(high) dendritic cells.

  2. ESAM levels clearly mirror the shift of hematopoietic stem cells (HSC (show FUT1 Proteins)) between quiescence and activation, and the intensity of expression is prominent in comparison with other HSC (show FUT1 Proteins)-related antigens.

  3. ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules.

  4. ESAM inactivation can reduce susceptibility to atherosclerosis by inhibiting plaque neovascularization and macrophage infiltration into the atheroma.

  5. findings support a model in which ESAM localizes to platelet contacts following platelet activation in order to limit thrombus growth and stability

  6. ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth

  7. The direct interaction between ESAM and MAGI-1 was confirmed by pull-down experiments. The two proteins formed stable complexes in transfected CHO cells.

  8. At endothelial tight junctions ESAM participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts.

  9. ESAM marks hematopoietic stem cells in murine fetal liver and will facilitate studies of hematopoiesis throughout life.

  10. Thus, ESAM may regulate albumin (show ALB Proteins) extravasation at the glomeruli and play a role in the initiation of diabetic nephropathy.

ESAM Protein Profile

Protein Summary

Can mediate aggregation most likely through a homophilic molecular interaction (By similarity).

Gene names and symbols associated with ESAM

  • endothelial cell adhesion molecule (ESAM)
  • endothelial cell adhesion molecule a (esama)
  • endothelial cell adhesion molecule (Esam)
  • endothelial cell-specific adhesion molecule (Esam)
  • 2310008D05Rik protein
  • ESAM protein
  • Esam1 protein
  • sc:d0254 protein
  • W117m protein

Protein level used designations for ESAM

endothelial cell adhesion molecule , endothelial cell-selective adhesion molecule , endothelial cell-specific adhesion molecule , zESAMa , 2310008D05Rik , HUEL (C4orf1)-interacting protein , LP4791 protein

GENE ID SPECIES
489309 Canis lupus familiaris
419707 Gallus gallus
616926 Bos taurus
451639 Pan troglodytes
712200 Macaca mulatta
799432 Danio rerio
300519 Rattus norvegicus
90952 Homo sapiens
69524 Mus musculus
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